Amaç: Entübe hastalarda nitrik oksitli (N2 O) düşük akımlı genel anestezide

Objective: Depending on the increase in inspired fractionated nitric oxidefraction (FiN2O), cuff pressures in intubated patients are increased with diffusioninto endotracheal cuff during low-flow anesthesia (LFA) with nitrousoxide (N2O). We compared pressures of air- and saline-inflated endotrachealtube cuffs during LFA with N2O in our study.Methods: We included 60 adult patients who were classified by the AmericanSociety of Anesthesiologists as I/II in the study. After induction of anesthesia,endotracheal cuffs of patients who were intubated were inflatedwith air (Group A=30) and saline (Group S=30) to 25 cm water. Thus, twoequal randomized groups were separated. The anesthesia technique wasmaintained with LFA and N2O. Endotracheal cuff pressures were continuouslymeasured with a pressure manometer, and inspired oxygen and N2Olevels and also 2 and 24 h after surgery for sore throat were recorded.Results: There was no significant difference about demographic and intraoperativedata between the groups. Cuff pressures were significantly higherin Group A than in Group S during all periods (p10 min=0.02, p<0.0001for others). Group S had significantly higher values than Group A whenmaximum cuff pressures were compared (37.60±3.16 vs. 29.96±3.34, respectively;p<0.0001). There was a 51.9% positive correlation between cuffpressure and FiN2O in Group A (r=0.519, p=0.048). Group Ahad significantlyhigher level than Group S at postoperative 2 and 24 h when groups werecompared for postoperative sore throat without swallowing and swallowing(p<0.05).Conclusion: Under LFA with N2O, endotracheal cuff pressures during operationand postoperative sore throat incidences in our study were significantlyhigher in Group S than in Group A.