Selami Aykut TEMİZ, Arzu ATASEVEN, İlkay OZER, Recep DURSUN, Siddika FİNDİK

Refractory Urticarial Vasculitis Responsive to Methotrexate: Could It Be a New Treatment Option?

Objective: Urticarial vasculitis is a chronic clinicopathologic entity characterized by clinically characterized urticarial rash, histopathologically

Keywords:

Urticarial vasculitis, methotrexate, omalizumab,

PDF

___

[1] Davis MDP, van der Hilst JCH. Mimickers of Urticaria: Urticarial Vasculitis and Autoinflammatory Diseases. J Allergy Clin Immunol Pract 2018;6(4):1162-70.
[2] Sjöwall C, Mandl T, Skattum L, Olsson M, Mohammad AJ. Epidemiology of hypocomplementaemic urticarial vasculitis (anti-C1q vasculitis). Rheumatology (Oxford) 2018; 57(8):1400- 07.
[3] Kavala M, Türkoğlu Z, Özlü E. Metotreksat ve dermatolojide klinik kullanımları. Med Med J 2014; 29:104-110.
[4] Sunderkötter C, De Groot K. Therapie von Vaskulitiden und Vaskulopathien. Der Hautarzt 2008; 59:382.
[5] Fiorentino DF. Cutaneous vasculitis. J Am Acad Dermatol 2003; 48:311-40.
[6] Polat AK, Belli AA, Karakus V, Dere Y. Deferasirox-induced urticarial vasculitis in a patient with myelodysplastic syndrome. An Bras Dermatol 2017; 92:59-61.
[7] Black AK. Urticarial vasculitis. Clinics in Dermatology 1999; 17:565-69.
[8] Katsambas A, Riga P. Purpura and vasculitis: unapproved treatments. Clin Dermatol 2002; 20:626-33.
[9] Khasnis A, Langford CA. Update on vasculitis. J Allergy Clin Immunol 2009; 123:1226-36.
[10] 1Shen S, O’Brien T, Yap LM, Prince HM, McCormack CJ. The use of methotrexate in dermatology: a review. Australas J Dermatol 2012; 53:1-18.
[11] Thomas-Golbanov C, Sridharan S. Novel therapies in vasculitis. Expert Opin Investig Drugs 2001; 10:1279-89.
[12] Stack PS. Methotrexate for urticarial vasculitis. Ann Allergy 1994; 72:36-38.
[13] Perez A, Woods A, Grattan CEH. Methotrexate: a useful steroidsparing agent in recalcitrant chronic urticaria. Br J Dermatol 2010; 162:191-94.
[14] Krause D, Schleusser B, Herborn G, Rau R. Response to methotrexate treatment is associated with reduced mortality in patients with severe rheumatoid arthritis. Arthritis Rheum 2000; 43:14-21.
[15] Cipriani P, Ruscitti P, Carubbi F, Liakouli V, Giacomelli R. Methotrexate: an old new drug in autoimmune disease. Expert Review of Clinical Immunology 2014; 10:1519-30.