Acute pancreatitis has been recognized since time primeval and has been described as the most terrible of all affliction that occurs in connection with the abdominal viscera. Early diagnosis and accurate staging of disease severity are important aims in the initial assessment and management of acute pancreatitis. To assess and the severity prediction of acute pancreatitis based on the evaluation of simplified entry criteria (Pulse > 100 beats/min, WBC>14.5 x 103 /dL, BUN>12 mg/dL, RBS>150 mg/dL) and compared it with the BISAP and Apache II scores for prediction of acute pancreatitis severity and prognosis. Patients with acute pancreatitis admitted over a period of 12 months at the Department of Surgery, Himalayan Institute of Medical Sciences (HIMS), Swami Ram Nagar, Dehradun were the subjects of the study. The distribution of the study subjects according to risk assessment of AP concerning Simplified Admis-sion Criteria showed that more than 50% of the cases were at lower risk followed by 37 (38.5%) cases were at higher risk. According to the APACHE II Score in this study, 57.3% of the total cases were at lower risk while 42.7% were at higher risk. Moreover, according to BISAP Score, 86.5% of the total cases were at lower risk while 13.5% were at higher risk. A significant association was observed between Simplified admission criteria and the APACHE II Sco-re. Compared with the APACHE II score and BISAP Score, the Simplified admission criteria showed relatable specificity and sensitivity for mortality. Mortality of 7.3% was recorded of the total cases recruited.In this study, results confirmed that Simplified Admission criteria were a useful tool for predicting mortality.