In the literature, the frequency for compensatory hyperhidrosis were usually given together for palmar and axillary hyperhidrosis. In our study, we tried to determine whether isolated axillary hyperhidrosis in patients undergoing one-stage bilateral single-port thoracoscopic sympathectomy developed more recurrence or compensatory hyperhidrosis than palmar hyperhidrosis. Between June 2012 and June 2018, we retrospectively analyzed one-stage bilateral single-port toracoscopic sympetectomy operations which were performed on 134 patients. The patients were evaluated with respect to the clinical characteristics, complications seen during or after the operation, and postoperative satisfaction. Complications were seen in 14 patients. Postoperative chylothorax, pleural effusion and horner syndrome were seen in one patient, and pneumothorax in 11 patients. Statistically, there was no significant difference between palmar hyperhidrosis and axillary hyperhidrosis in terms of gender, family history and postoperative complications. However, there was a statistically significant difference in body mass index, recurrent hyperhidrosis in hand or axillary region, compensatory hyperhidrosis and satisfaction. As a result, patients with axillary hyperhidrosis with a body mass index of 25 kg/m2 or higher have postoperative recurrence, compensant hyperhidrosis and dissatisfaction at a higher rate than palmar hyperhidrosis. We believe that this high risk should be reported to the patient before surgery.