Vitiligo ile Serum 25(OH) D Vitamini İlişkisi

Giriş ve Amaç: Vitiligo hastalarında serum 25-hidroksivitamin D (25 (OH) D) seviyelerini incelemek ve sağlıklı bireylerden oluşan kontrol grubu ile karşılaştırarak serum 25 (OH) D seviyeleri ile vitiligo arasında olası bir ilişki olup olmadığı belirlemektir. Gereç ve Yöntemler: Ekim 2017-Mart 2018 tarihleri arasında vitiligo tanısı konulan 45 hasta ve 83 sağlıklı birey çalışmaya alındı.Çalışma grubunun serum D vitamini düzeyleri yüksek performans likit kromatografi yöntemi ile değerlendirildi.Ayrıca serum paratiroid hormon kalsiyum, fosfor, alkalen fosfataz seviyeleri de incelendi. Bulgular: Çalışmamıza 9-55 yaş(ort 28,22 ± 7,1 ) arasındaki 45 hasta ve kontrol grubunda 18-58 yaş arası(ortalama: 34,38 ± 7.3) 83 sağlıklı birey katılmıştır.Vitiligolu hastalarda serum 25 (OH) D seviyeleri ortalama 22,19 ng / ml (8,42-80,1 ng / ml) olarak belirlendi. Kontrol grubunda ise serum 25 (OH) D seviyeleri ortalama 23,4 ng /ml(3-69,2 ng / ml) olarak belirlendi.. Her iki grup arasında serum D vitamini düzeyi arasında istatistiksel olarak anlamlı bir fark yoktu(p> 0.05). Sonuç: Bu sonuçlar ışığında serum 25(OH) D vitamini ile vitiligo arasında herhangi bir ilişki bulunmamıştır.

Anahtar Kelimeler:

D vitamini, Vitiligo, ilişkisi

Association Between 25(OH) Vitamin D and vitiligo

Objective: To evaluate serum 25-hydroxyvitamin D (25 (OH) D) levels in vitiligo patients and to determine whether there is a possible relationship between serum 25 (OH) D levels and vitiligo by comparing it with a control group of healthy individuals. Material and Methods: 45 patients and 83 healthy individuals diagnosed with vitiligo between October 2017 and March 2018 were included in the study. Serum vitamin D levels of the study group were evaluated by high performance liquid chromatography method. Serum parathyroid hormone calcium, phosphorus, alkaline phosphatase levels were also examined. Results: 45 patients between 9-55 years old (mean 28.22 ± 7.1) and 83 healthy individuals between 18-58 years old (mean: 34.38 ± 7.3) in the control group participated in our study. Serum 25 (OH) D levels were determined as an average of 22.19 ng / ml (8.42-80.1 ng / ml) in patients with vitiligo. In the control group, serum 25 (OH) D levels were determined to be 23.4 ng / ml (3-69.2 ng / ml). There was no statistically significant difference between the serum vitamin D levels between the two groups (p> 0.05 ). Conclusion: In the light of these results, no relationship was found between vitiligo and serum 25 (OH) vitamin D.

Keywords:

Vitamin D, Vitiligo, Relationship,

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