Dursun TOPAL, Berat UĞUZ, İsmet ZENGİN, Selvi COŞAR, Selma TİRYAKİOĞLU

COVID-19 şüpheli veya kesin tanısı ile yatışı yapılan hastalarda kalp hızı değişkenliği: Sağlıklı kontrollere göre ve proinflamatuvar sitokinler açısından bir retrospektif analiz

Giriş ve Amaç: Bu çalışma, Koronavirüs hastalığı-2019 (COVID-19) şüpheli veya kesin tanısı ile yatışı yapılan hastalarda kalp hızı değişkenliğinin (KHD) sağlıklı kontrollerle kıyaslanması ve proinflamatuvar sitokinler bağlamında değerlendirilmesi amacı ile tasarlandı. Gereç ve Yöntemler: Bu çalışmaya, 3 alt gruptan oluşan (53 kesin COVID-19 tanısı almış hasta, 42 şüpheli COVID-19 tanısı almış hasta ve 20 sağlıklı kontrol) toplam 115 denek dahil edildi. Hasta demografik özellikleri, inflamatuvar belirteçler (C-reaktif protein [CRP], D-Dimer, ferritin ve prokalsitonin) ve 24-saat Holter monitorizasyon parametrelerine ait veriler kaydedildi. Bulgular: Holter monitorizayonu parametrelerinin hiçbiri, şüpheli ve kesin COVID-19 tanısına sahip gruplar arasında anlamlı fark göstermedi. Şüpheli ve kesin COVID-19 tanılı her iki grupta, bütün NN intervallerinin standart sapması (SDNN, her biri için p

Anahtar Kelimeler:

COVID-19; kalp hızı değişkenliği, zaman-bağımlı indeksler, frekans-bağımlı indeksler şüpheli tanı; kesin tanı; proinflamatuvar sitokinler

Heart Rate Variability in Hospitalized Patients with Suspected or Confirmed Diagnosis of COVID-19: A Retrospective Analysis in Comparison to Healthy Controls and in Relation to Proinflammatory Cytokines

Objective: This study was designed to evaluate heart rate variability (HRV) in hospitalized patients with suspected or confirmed diagnosis of coronavirus disease-2019 (COVID-19) in comparison to healthy controls and in relation to proinflammatory cytokines. Materials and Methods: A total of 115 subjects consisting of 3 subgroups (53 patients with confirmed diagnosis of COVID-19, 42 patients with suspected diagnosis of COVID-19 and 20 healthy controls) were included in this study. Data on patient demographics, inflammatory markers (C-reactive protein [CRP], D-Dimer, ferritin, procalcitonin) and the 24-h Holter monitoring parameters were recorded. Results: None of the Holter monitoring parameters differed significantly between patients with suspected COVID-19 and those with confirmed COVID-19. In both suspected COVID-19 and confirmed COVID-19 groups, standard deviation of all NN intervals (SDNN, p

Keywords:

COVID-19, heart rate variability, time domain indices, frequency-domain indices, suspected diagnosis, confirmed diagnosis, proinflammatory cytokines, COVID-19, heart rate variability, time domain indices, frequency-domain indices suspected diagnosis, confirmed diagnosis, proinflammatory cytokines,

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