Aslıhan YURTKAL, Müjde CANDAY, Hatice BEŞEREN

ENDOMETRİALHİPERPLAZİ VE ENDOMETRİAL POLİPLERİN P16 STROMAL EKSPRESYONU İLE İLİŞKİSİ: DERLEME

Son zamanlarda endometriyal poliplerle ilişkili endometriyal seröz adenokarsinomların incelenmesinde p16 stromal ekspresyonu bildirilmiştir. Bu nedenle endometrial polipler bazı kaynaklarfa preneoplastik oluşumlar olarak tanımlanmaktadır. Endometrial poliplerdeki bu farklı stromal hücre ekspresyonları nedeniyle, derleme yazımızda endometrial hiperplazi ve endometrial poliplerde stromal dokudaki p16 ekspresyonlarının ayırıcı tanıdaki yerini sunmak istedik.

Anahtar Kelimeler:

p16, İmmünohistokimya, Ekspresyon

ENDOMETRIALHYPERPLASIA AND ITS RELATIONSHIP WITH P16 STROMAL EXPRESSION OF ENDOMETRIAL POLYPS: REVIEW

Recently, p16 stromal expression has been reported in the examination of endometrial serous adenocarcinomas associated with endometrial polyps. Therefore, endometrial polyps are defined as preneoplastic formations in some textbooks. Due to these different expressions of stromal cells in endometrial polyps, we wanted to present the place of p16 expressions in stromal tissue in endometrial hyperplasia and endometrial polyps in the differential diagnosis in our review article.

Keywords:

p16, Immunohistochemistry, Expression,

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