TİROİDEKTOMİ SONRASI REZİDÜ DOKU TESPİT EDİLEN DİFERANSİYE TİROİD KARSİNOMLU HASTALARIN BAŞVURU ÖZELLİKLERİ, TEDAVİ VE TAKİP SONUÇLARI
Amaç: Postoperatif radyoaktif iyot (RAI) ablasyonu, diferansiye tiroid karsinomlarında (DTK) tiroidektomi sonrası ta-mamlayıcı tedavi seçeneklerinden birisidir. Tiroidektomi sonrası rezidü dokunun değerlendirilmesi, postoperatif RAIablasyonunun etkinliği açısından önemlidir. Çalışmamızda total tiroidektomi (TT) sonrası rezidü doku tespit edilmişDTK’lı olgularda başvuru özellikleri, tedavi ve takip sonuçlarını retrospektif olarak inceledik.Hastalar ve Metod: Ocak 2014-Temmuz 2018 tarihleri arasında tiroidektomi sonrası patoloji sonucu DTK olarakraporlanan, postoperatif sintigrafide rezidü tiroid dokusu tespit edilmiş 187 (165 kadın, 22 erkek) hasta çalışmayadahil edildi. Yaş, cinsiyet, ultrasonografi bulguları, ince iğne aspirasyon biyopsi (İİAB) sonuçları, yapılan cerrahi giri-şimin tipi, tümör çapı, multifokalite, postoperatif serum tiroglobulin (Tg) düzeyi, tiroid sintigrafisi, RAI ablasyonu velokorejyonel rekürrens gibi parametreler Windows için SPSS 18.0 programı ile Mann Whitney-U, Kruskal Wallis veki-kare testleri kullanılarak değerlendirildi. P değeri < 0,05 ise anlamlı kabul edildi.Bulgular: Tüm hastaların tiroidektomi spesimenlerinin histopatolojik değerlendirme sonucu DTK iken, ameliyat ön-cesi sadece 44’ünde (%24) İİAB sonucu malign ya da malignite şüphesi olarak raporlanmıştı. 45 yaşından büyükhasta grubunda papiller tiroid mikrokarsinomu (PTMK) anlamlı olarak daha sık gözlendi (p
Presentations and Outcomes of Patients with Residual Tissue After Thyroidectomy for Differentiated Thyroid Carcinoma
Aim: Postoperative radioactive iodine (RAI) ablation is one of the options for complementary treatment after thyroidectomy of differentiated thyroid carcinoma (DTC). The evaluation of the residual tissue after thyroidectomy is important for the effectiveness of RAI ablation. In our study, we evaluate the presentation and outcomes of the patients with residual thyroid tissue and aimed to identify the risk factors related with the presence of the residual thyroid tissue. Patients and Methods: 187 (165 female, 22 male) patients, were reported as DTC and postoperative scintigraphy revealed residual thyroid tissue between January 2014 and July 2018, were enrolled in the study. The parameters including age, gender, ultrasonography findings, fine needle aspiration cytology (FNAC) reports, type of the surgery, tumour diameter, multifocality, postoperative serum thyroglobulin (Tg) levels, thyroid scintigraphy, RAI ablation, and locoregional recurrence were compared by Mann Whitney-U, Kruskal Wallis, and qi-square test in SPSS 18.0 for Windows software. P value is accepted as significant if below 0.05. Results: Thyroidectomy specimens of all patients were reported as DTC, Preoperatively only in 44 (24%) patients were reported as malign or suspicion of malignancy according to the results of FNAC. Papillary thyroid microcarcinoma (PTMC) was significantly more common in the group of patients older than 45 (p
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