Mehmet Özgür PINARBAŞLI, Ercan KAYA, Melek Kezban GÜRBÜZ, Mustafa AÇIKALIN, Müberra PEHLİVAN

NAZAL KAVİTE KAYNAKLI RESPİRATUAR EPİTELYAL ADENOMATOİD HAMARTOM: BİR OLGU SUNUMU

Respiratuar epitelyal adenomatoid hamartom benign bir sinonazal patolojidir. Oldukça nadir gö- rülür ve çoğunlukla nazal kavitenin posteriorunda yerleşim gösterir. Klinik olarak nazal polip, ant- rokoanal polip ve inverted papillom gibi bazı sinonazal hastalıklarla karıştırılabilir. Bu hastalıkların ayırıcı tanısında respiratuar epitelyal adenomatoid hamartomun akılda tutulması klinik açıdan önemlidir. Çünkü respiratuar epitelyal adenomatoid hamartomlu olgularda lezyonun konservatif bir şekilde lokal eksizyonu yeterlidir. Bu yazıda nazal kavitenin posteriorunda yerleşim gösteren ve endoskop eşliğinde eksize edilen bir respiratuar epitelyal adenomatoid hamartom olgusu sunul- muştur.

Epithelial Based Respiratory Nasal Cavity Adenomatoid Hamartoma: A Case Report

ABSTRACT Respiratory epithelial adenomatoid hamartoma is a benign sinonasal pathology. It is seen quite rarely and often is localized in the posterior nasal cavity. Clinically, nasal polyps, antrochoanal polyps and inverted papillomas are of sinonasal diseases. In the differential diagnosis of these diseases, respiratory epithelial adenomatoid hamartoma evaluation is clinically important. Because of respiratory epithelial adenomatoid hamartoma lesions in patients, conservative local excision is sufficient. In this article we presented a respiratory epithelial adenomatoid hamartoma case localized in the posterior nasal cavity that is resected under endoscopy.

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1. Weinreb I. Low grade glandular lesions of the sinonasal tract: a focused review. Head Neck Pathol. 2010; 4(1):77-83.
2. Fitzhugh VA, Mirani N. Respiratory epithelial adenomatoid hamartoma: a review. Head Neck Pathol. 2008; 2(3):203-8.
3. Khan RA, Chernock RD, Lewis JS Jr. Seromucinous hamartoma of the nasal cavity: a report of two cases and review of the literature. Head Neck Pathol. 2011; 5(3):241-7.
4. Cardesa A, Alos L, Franchi A. Nasal Cavity and Paranasal Sinuses. In: Cardesa A, Slootweg PJ, editors. Pathology of the head and neck. Springer-Verlag Berlin Heidelberg, 2006 pp.39-72.
5. Wenig BM, Heffner DK. Respiratory epithelial adenomatoid hamartomas of the sinonasal tract and nasopharynx: a clinicopathologic study of 31 cases. Ann Otol Rhinol Laryngol. 1995; 104(8):639-45.
6. Avilés Jurado FX, Guilemany Toste JM, Alobid I, Alós L, Mullol I Miret J. The importance of the differential diagnosis in rhinology: respiratory epithelial adenomatoid hamartoma of the sinonasal tract. Acta Otorrinolaringol Esp. 2012;63(1):55-61.
7. Seol JG, Livolsi VA, O’Malley BW Jr, Chen JY, Loevner LA. Respiratory epithelial adenomatoid hamartoma of the bilateral olfactory recesses: a neoplastic mimic? AJNR Am J Neuroradiol. 2010 ; 31(2):277-9.
8. Himi Y, Yoshizaki T, Sato K, Furukawa M. Respiratory epithelial adenomatoid hamartoma of the maxillary sinus. J Laryngol Otol. 2002; 116(4):317-8.
9. Kessler HP, Unterman B. Respiratory epithelial adenomatoid hamartoma of the maxillary sinus presenting as a periapical radiolucency: a case report and review of literature. Oral Surg Oral Med Oral Pathol Radiol Endod. 2004;97(7): 607-12.
10. Athre R, Ducic Y. Frontal sinus hamartomas. Am J Otolaryngol. 2005; 26(5): 419-21.
11. Ozolek JA, Hunt JL. Tumor suppressor gene alterations in respiratory epithelial adenomatoid hamartoma (REAH): comparison to sinonasal adenocarcinoma and inflamed sinonasal mucosa. Am J Surg Pathol. 2006; 30(8): 1576–1580.
12. Gajda M, Zagolski O, Jasztal A, Lis GJ, Pyka-Fosciak G, Jan A Litwin. Respiratory epithelial adenomatoid hamartoma of the anterior nasal septum a rare localisation of an unusual tumour in a child: a case report. Cases J. 2009; 2(9): 8151.
13. Cao Z, Gu Z, Yang J, Jin M. Respiratory epithelial adenomatoid hamartoma of bilateral olfactory clefts associated with nasal polyposis: three cases report and literature review. Auris Nasus Larynx. 2010; 37(3):352-6.