HEPATOSELLÜLER KARSİNOMDA DİFERANSİYASYON DERECESİNİN ADC HİSTOGRAM ANALİZ SONUÇLARI VE KONTRASTLI MANYETİK REZONANS GÖRÜNTÜLEME BULGULARI İLE İLİŞKİSİ The Relationship of Differentiation Grade in Hepatocellular Carcinoma with ADC Histogram Analysis Results and Contrast- Enhanced Magnetic Resonance
ÖZET
Amaç: Hepatosellüler karsinomda (HSK) diferansiyasyon derecesinin apparent diffusion coefficient (ADC)
histogram analizi sonucunda elde edilen kantitatif verilerle ve kontrastlı manyetik rezonans görüntüleme
(MRG) bulgularıyla ilişkisini araştırmak amaçlanmıştır.
Gereç ve Yöntemler: Aralık 2014–Aralık 2017 yılları arasında tetkik edilen 18 yaş ve üzerindeki olguların üst
abdomen MR görüntüleri geriye dönük incelendi. Hepatosellüler karsinom tanısı almış 41 tümör histopatoloji
sonucuna göre kötü, orta ve iyi diferansiye olmak üzere 3 gruba ayrıldı. Her diferansiyasyon grubu için
olguların demografik özellikleri, MRG bulguları ve ADC ölçümleri kaydedildi.
Bulgular: Kötü [n: 14 (%34)], orta [n: 15 (%37)] ve iyi [n: 12 (%29)] diferansiye HSK’larda minimum, ortalama
ve maksimum ADC değerleri sırasıyla kötü için 0,59 (0,47-0,64); 0,75 (0,72-0,86); 1,00 (0,88-1,24)x10-3
mm2/s, orta için 0,67 (0,56-0,79); 0,97 (0,75-1,00); 1,17 (1,05-1,31)x10-3 mm2/s, iyi için 0,96 (0,82-0,97); 1,12
(1,01-1,24); 1,40 (1,29-1,62)x10-3 mm2/s olarak hesaplandı. Minimum ADC için kötü-orta, kötü-iyi, orta-iyi
gruplar arasında, ortalama ADC için orta-iyi, kötü-iyi gruplar arasında ve maksimum ADC için yalnızca kötü-
orta gruplar arasında istatistiksel anlamlı farklılık saptanmıştır (p
Effect of Lumbar Spinal Stenosis on Pain, Daily Activities of Living and Muscular Activity
Objective: The aim of this study was investigate whether or not lumbar spinal stenosis (LSS) had effect onpain, daily living activities and muscular activation.Material and Methods: Individuals diagnosed as lumbar spinal stenosis with average of 55,19 ± 10,41 yearsold was included to the study. Individuals were divided into three groups as mild, moderate and severe bydural pouch magnetic resonance imaging inspection. Resting and activity pain assessment was made withvisual analog scale (VAS), muscular activity of the rectus femoris, biceps femoris, tibialis anterior and medialpart of the gastrocnemius was measured with surface electromyography (sEMG), and daily living activitieswas assessed with Oswestry lower back disability index.Results: Significant difference was found in VAS and ODI values according to the LSS severity (p<0,05). Painin resting and during activities were different from each other (p<0,05). It was found that individuals withsevere LSS had more lower limb muscular activity compared to moderate and mild individuals, and individuals with moderate LSS had more muscular activity compared to the mild ones (p<0,05).Conclusion: It was determined that disability and pain increases as the LSS severity increases. It was observed that more pain occurs while patients are active. It was concluded that early diagnosis of LSS is importantand necessary preventions should be taken to prevent further increase in severity.
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