Aykut BAŞER, Mehmet Murat BAYKAM, Mustafa Serdar ÇAĞLAYAN, Cemil AYDIN, Muhammet YAYTOKGİL, Musa EKİCİ

Voiding Dysfunctions and Prevention after Prostate Biopsy. Prospective Observational Study

The possible side effects of transrectal ultrasonography-guided prostate biopsy (TRUS-Bx), which is one of the most common procedure of urology practice, are common but tend to limit themselves. TRUS-Bx may be associated with Lower Urinary System Symptoms (LUTS). We aimed to investigate the effects of TRUS-Bx on LUTS and the factors that decrease or increase these effects and to provide information about the exposure periods of these factors. This study is a prospective observational study involving patients undergoing prostate biopsy between August 1st, 2019 to 2020. Detailed history was obtained and physical examinations were evaluated from all patients. Patients' age, PSA levels, prostate volumes, Body-Mass-Index measurements and use of alpha blocker were recorded. The effects of recorded information of patients with prostate biopsy on LUTS and uroflowmetry parameters were investigated. A total of 143 patients were included in the study after determining the exclusion criteria. A significant correlation was found only between Qmax changes after TRUS-Bx and the use of alpha blockers. All patients, have decreased Qmax flow rate observed at postprocedure 1th day compared to baseline values. During the controls performed in the 4th week, while the decrease in patients using alpha blockers reached a significantly higher value than its baseline value, it could not return to its baseline value in patients who do not use alpha blockers. Prostate biopsy is expected to cause a temporary LUTS. The effects on this LUTS can be corrected with the use of alpha blockers.

Keywords:

Prostate Biopsy, Voiding Dysfunction, LUTS, Alpha Blockers, International prostate symptom score,

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