Determination of Antimicrobial Activity of Various Plant Essential Oils on Vancomycin Resistant Enterococci (VRE) and Some Pathogenic Microorganisms

In this study, it was aimed to determine the anti-bacterial activities of plant essential oils such as thyme, rosemary, sage, linden, black seed, bay leaf, peppermint, parsley, cinnamon and oleagen on vancomycin resistant enterococci (VRE) and pathogenic microorganisms of clinical importance. In the study, the inhibition zones of the plant extract of 10 plants prepared at 2.5 and 5 mg / mlconcentrations of VRE and various pathogenic microorganisms were detected by Disk Diffusion and Agar Well Diffusion Method. Following this, Minimal Inhibition Concentration (MIC) values of these extracts were determined. The activities of plant extracts on DNA and Gas Chromatography-Mass Spectrometry (GC-MS) analyzes were also performed. According to the data obtained, it was determined that the extracts of rosemary and sage plants showed high antibacterial effect against pathogenic bacteria. The rosemary extract was found to be the most effective extract on VRE strains, as well as medium-grade antibacterial effects on the VRE strains in oleaster, linden, thyme and mint extracts. It was also determined that extracts from different plants did not cause any change in the structure of DNA. In our study, it was determined that plant extracts that are especially effective on VRE strains have the potential to be used in the treatment of VRE. The results of this study should be taken into account in the research of drugs that can be used in the treatment of VRE and more in vitro and in vivo research should be carried out in this field.

Keywords:

Vancomycin-resistant enterococci (VRE), Plant volatile oils, Antibacterial activity,

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