Mentha longifolia (L.) Hudson subsp. typhoides (Briq.) Harley var.typhoides’in Hidroksil Radikali ve Hipokloröz Asit Süpürme Aktiviteleri

Çalışmada Mentha longifolia (L.) Hudson subsp. typhoides (Briq.) Harley var. typhoides etanol ekstraktının totalantioksidan kapasitesi ile hidroksil radikali (OH.) ve hipokloröz asit(HOCI) süpürme aktivitesinindeğerlendirilmesi amaçlandı. M. longifolia subsp. typhoides var. typhoides total antioksidan kapasitesi 569±8.57mg AAE/gr olarak belirlendi. Mentha longifolia (L.) Hudson subsp. typhoides (Briq.) Harley var. typhoides etanolekstraktının, hidroksil radikali ve hipokloröz asit süpürücü aktiviteleri incelendiğinde IC50 değerleri ise sırasıyla75.09±2.47 ve 201.43±17.99 µg/mL olarak tesbit edildi. Sonuç olarak M. longifolia subsp. typhoides var. typhoidesetanol ekstraktının total antioksidan kapasitesi ve radikal süpürme aktivitesi değerlendirildiğinde bitkininpotensiyel bir doğal antioksidan kaynağı olabileceği söylenebilir. Ayrıca, oksidatif strese bağlı olarak ortayaçıkabilecek birçok hastalığın önlenmesi veya tedavisinde terapötik ajanlar olarak yüksek etkiye sahip olabileceğidüşünülmektedir.

Hydroxyl Radical and Hypochlorous Acid Scavenging Activity of Mentha longifolia (L.) Hudson subsp. typhoides (Briq.) Harley var. typhoides

The purpose of this study was to investigate the antioxidant potential with hydroxyl radical(OH. ) and hypochlorous acid(HOCI) scavenging activity of the ethanol extract of Mentha longifolia (L.) Hudson subsp. typhoides (Briq.) Harley var. typhoides. The total antioxidant activity was found to be 569 ± 8.57 mg AAE/gr of extract. Mentha longifolia (L.) Hudson subsp. typhoides (Briq.) Harley. IC50 values of typhoides ethanol extract, hydroxyl radical and hypochlorous acid were determined as 75.09±2.47 and 201.43±17.99 µg/mL respectively. As a result, the total antioxidant capacity and radical scavenging activity of the plant ethanol extract can be considered as a potential natural antioxidant source of the plant. It is also thought that it may have high effect as therapeutic agents in the protection or treatment of many diseases due to oxidative stres.

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