New Predictive Parameters of Bell"s Palsy: Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio
New Predictive Parameters of Bell"s Palsy: Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio
Background: Bell’s palsy is the most frequent cause of unilateral facial paralysis. Inflammation is thought to play an important role in the pathogenesis of Bell’s palsy. Aims: Neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) are simple and inexpensive tests which are indicative of inflammation and can be calculated by all physicians. The aim of this study was to reveal correlations of Bell’s palsy and degree of paralysis with NLR and PLR. Study Design: Case-control study. Methods: The retrospective study was performed January 2010 and December 2013. Ninety-nine patients diagnosed as Bell’s palsy were included in the Bell’s palsy group and ninety-nine healthy individuals with the same demographic characteristics as the Bell’s palsy group were included in the control group. As a result of analyses, NLR and PLR were calculated. Results: The mean NLR was 4.37 in the Bell’s palsy group and 1.89 in the control group with a statistically significant difference (p<0.001). The mean PLR was 137.5 in the Bell’s palsy group and 113.75 in the control group with a statistically significant difference (p=0.008). No statistically significant relation was detected between the degree of facial paralysis and NLR and PLR. Conclusion: The NLR and the PLR were significantly higher in patients with Bell’s palsy. This is the first study to reveal a relation between Bell’s palsy and PLR. NLR and PLR can be used as auxiliary parameters in the diagnosis of Bell’s palsy. JEL code: I180 Health
Keywords:
Bell’s palsy inflammation, lymphocytes, neutrophils, platelets,
___
- 1. Bleicher JN, Hamiel S, Gengler JS, Antimarino J. A survey of facial paralysis: etiology and incidence. Ear Nose Throat J 1996;75:355-8.
- 2. Hughes GB. Practical management of Bell’s palsy. Otolaryngol Head Neck Surg 1990;102:658-63.
- 3. Peitersen E. The natural history of Bell’s palsy. Am J Otol 1982;4:107-11.
- 4. Yilmaz M, Tarakcioglu M, Bayazit N, Bayazit YA, Namiduru M, Kanlikama M. Serum cytokine levels in Bell’s palsy. J Neurol Sci 2002;197:69-72. [CrossRef]
- 5. Kefalidis G, Riga M, Argyropoulou P, Katotomichelakis M, Gouveris C, Prassopoulos P, et al. Is the width of the labyrinthine portion of the fallopian tube implicated in the pathophysiology of Bell’s palsy?: a prospective clinical study using computed tomography. Laryngoscope 2010;120:1203-7. [CrossRef]
- 6. Bhat T, Teli S, Rijal J, Bhat H, Raza M, Khoueiry G, et al. Neutrophil to lymphocyte ratio and cardiovascular diseases: a review. Expert Rev Cardiovasc Ther 2013;11:55-9. [CrossRef]
- 7. Proctor MJ, McMillan DC, Morrison DS, Fletcher CD, Horgan PG, Clarke SJ. A derived neutrophil to lymphocyte ratio predicts survival in patients with cancer. Br J Cancer 2012;107:695-9. [CrossRef]
- 8. Wang D, Yang JX, Cao DY, Wan XR, Feng FZ, Huang HF, et al. Preoperative neutrophil-lymphocyte and platelet-lymphocyte ratios as independent predictors of cervical stromal involvement in surgically treated endometrioid adenocarcinoma. Onco Targets Ther 2013;6:211-6.
- 9. Bucak A, Ulu S, Oruc S, Yucedag F, Tekin MS, Karakaya F, et al. Neutrophil-to-lymphocyte ratio as a novel-potential marker for predicting prognosis of Bell palsy. Laryngoscope 2014;124:1678-81. [CrossRef]
- 10. Morris AM, Deeks SL, Hill MD, Midroni G, Goldstein WC, Mazzulli T, et al. Annualized incidence and spectrum of illness from an outbreak investigation of Bell’s palsy. Neuroepidemiology 2002;21:255-61. [CrossRef]
- 11. Greco A, Gallo A, Fusconi M, Marinelli C, Macri GF, de Vincentiis M. Bell’s palsy and autoimmunity. Autoimmun Rev 2012;12:323-8. [CrossRef]
- 12. Ulu S, Ulu MS, Bucak A, Ahsen A, Yucedag F, Aycicek A. Neutrophil-to-lymphocyte ratio as a new, quick, and reliable indicator for predicting diagnosis and prognosis of idiopathic sudden sensorineural hearing loss. Otol Neurotol 2013;34:1400-4. [CrossRef]
- ISSN: 2146-3123
- Başlangıç: 2015
- Yayıncı: Erkan Mor
Sayıdaki Diğer Makaleler
Doğan ATAN, Aykut İKİNCİOĞULLARI, Kürşat Murat ÖZCAN, Sabri KÖSEOĞLU
Serpil TAHERİ, Halit CANATAN, Bilgehan AYGEN, Orhan YILDIZ, Keziban KORKMAZ, Gökmen ZARARSIZ
Ahmet ŞAHPAZ, Binnur ÖNAL, Ahmet YEŞİLYURT, Ünsal HAN, Tuncay DELİBAŞI
Dušan GRUJİĆ, Aleksandar KNEŽEVİĆ, Svetlana VOJVODİĆ, Bojana GRUJİĆ
Clinical Implications of Nasal Septal Deformities
Ranko MLADİNA, Neven SKİTARELİĆ, Gorazd POJE, Marin ŠUBARİĆ