Mean Platelet Volume in Early Diagnosis of Adnexal Torsion

Background: Adnexal torsion (AT) is among the gyne-cological emergencies; more common in reproductive age, if diagnosed late, this can cause ovarian failure and infertility, but rarely thrombophlebitis and peritonitis. Despite these severe complications, preoperative diag-nostic tests are not enough for early diagnosis. There are certain pieces of literature on the subject that reveal changes in mean platelet volume (MPV) values occur in inflammatory and ischemic diseases and that these changes have diagnostic and prognostic significance. However, there are no studies investigating this rela-tionship with adnexal torsion.Aims: The aim of the study is to investigate the diag-nostic and prognostic significance of the mean platelet volume value in the early diagnosis of patients with ad-nexal torsion.Study Design: Case-control study.Methods: Pre-operative demographic data, MPV, leu-kocyte count and neutrophils to lymphocytes (N/L) ra-tio in the blood samples of 51 patients, who were oper-ated on preliminary adnexal torsion and diagnosed as adnexal torsion with a benign ovarian cyst (AT group) were retrospectively compared with those of 50 pa-tients who were operated upon because of benign ovar-ian cysts and without torsion (control group) at this hospital between 2006 and 2014.Results: The mean MPV level was found to be 8.1 (7.1-10.7) fL in the AT group and 7.9 (6.6-10.2) fL in the control group; no statistically significant difference was found between the groups (p>0.05).Leukocyte count and N/L ratio in the AT group were, on average, 12x103/mm3 and 82% respectively and in control group; they were, on average, 7.2x103/mm3 and 59%, respectively. A statistically significant increase was found in the leukocyte count and N/L ratio of the AT group compared to the control group (p0.05). No correlation was detected between the MPV, platelet and leukocyte counts. The sensitivity of the leukocytosis to the AT cases was found to be 66.7%, and selectivity was 94%.Conclusion: The AT diagnostic and prognostic impor-tance of MPV value has not been determined in this study

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