Hasan CAN, Ahmet KORKMAZ, Metin SARIKAYA, Ramazan ÇETİNKAYA, Funda SARI, Ayşe GÜNEŞ, Nur TUKEL, Mustafa EREN

Hypokalemic rhabdomyolysis induced acute renal failure as a presentation of coeliac disease

Erişkin çöliak hastalığı sıklıkla kronik ishal ve kilo kaybı gibi klasik semptomlar olmaksızın görülür. Biz ishale bağlı hayatı tehdit edici hipokalemi, akut böbrek yetmezliği ve akut quadripleji gelişen 31 yaşında bir kadın çöliak hastası sunmaktayız. Literatürde hipokalemik rabdomiyolizli çöliak hastaları sunulmasına karşın akut böbrek yetmezliği gelişmiş hasta bildirilmemiştir. Bu vaka hipokalemik rabdomiyolize bağlı akut böbrek yetmezliği ile başvuran ilk çöliak hastasıdır. Şiddetli ishale bağlı hipokalemik rabdomiyoliz ile başvuran akut böbrek yetmezliği vakalarında anti gliadin IgA antikoru negatif olsa bile ayırıcı tanıda çöliak hastalığı da düşünülmelidir.

Çöliak hastalığı prezentasyonu olarak hipokalemik rabdomiyoliz ilişkili akut böbrek yetmezliği

Adult coeliac disease commonly presents without classical symptoms as chronic diarrhea and weight loss. We describe the case of a 31-year-old woman with persistent life-threatening hypokalemia, acute renal failure, and acute quadriplegia due to diarrhea that had continued for one month. Although there are cases of coeliac disease diagnosed with hypokalemic rhabdomyolysis in the literature, none of the cases developed acute renal failure. This is the first case in the literature diagnosed with acute renal failure due to hypokalemic rhabdomyolysis as a presentation of coeliac disease. In acute renal failure cases that present with hypokalemic rhabdomyolysis due to severe diarrhea, coeliac disease should be considered as a differential diagnosis despite the negative antigliadin IgA antibody.

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