Effects of Caudal and Penile Blocks on the Complication Rates of Hypospadias Repair

Effects of Caudal and Penile Blocks on the Complication Rates of Hypospadias Repair

Background: The major influencing factors for complications during hypospadias repair are the original location of the meatus, previous urethral surgery, surgical technique, and surgeon’s experience. While the effect of the technique of regional analgesia on complication rates has been considered in some studies, this issue remains controversial. Aims: To determine the effect of caudal block and penile block on complication rates of hypospadias repair in patients with subcoronal hypospadias. Study Design: Retrospective cross-sectional study.Methods: Data of children who underwent hypospadias repair between 2011 and 2019 in our clinic (n = 770) were reviewed retrospectively. Only patients with subcoronal hypospadias and who underwent tubularized incised plate urethroplasty, performed by the same two experienced surgeons (n = 279), were included in the study. The exclusion criteria were incomplete data and follow-up time shorter than 12 months. Data of 279 patients were analyzed. Patients were divided into two groups according to the analgesia type: caudal block (n = 95) and penile block (n = 184), and complication rates were compared between these groups. Results: The median age was 36 months in the caudal block group and 30 months in the penile block group (P = 0.390). The median follow-up times were 54 and 42.7 months in the caudal and penile block groups, respectively. Total complication rates did not differ significantly between the groups and were determined as 10.5% and 12.5% in the caudal and penile groups, respectively. Urethrocutaneous fistula rates were observed as 2.1% and 4.3% (p=0.50). None of the patients had penile chordee and no penile plication was performed in the whole group. Conclusion: This study shows that there is no increase in post-repair complications in patients with subcoronal hypospadias who underwent caudal block.

___

  • Bhat A. General considerations in hypospadias surgery. Indian J Urol. 2008;24:188- 194. [CrossRef]
  • Spinoit AF, Poelaert F, Van Praet C, Groen L-A, Laecke EV, Hoebeke P. Grade of hypospadias is the only factor predicting for re-intervention after primary hypospadias repair: A multivariate analysis from a cohort of 474 patients. J Pediatr Urol. 2015;11: 70.e1-70.e6. [CrossRef]
  • Sheng X, Xu D, Wu Y, Yu Y, Chen J, Qi J. The risk factors of urethrocutaneous fistula after hypospadias surgery in the youth population. BMC Urol. 2018;18:64. [CrossRef]
  • Pfistermuller KLM, McArdle AJ, Cuckow PM. Meta-analysis of complication rates of the tubularized incised plate (TIP) repair. J Pediatr Urol. 2015;11:54- 59. [CrossRef]
  • Kundra P, Yuvaraj K, Agrawal K, Krishnappa S, Kumar LT. Surgical outcome in children undergoing hypospadias repair under caudal epidural vs penile block. Paediatr Anaesth. 2012;22:707-712. [CrossRef]
  • Haydar B, Freed K. Hypospadias repair and caudal analgesia: biases and myths hinder meaningful meta-analysis. Reg Anesth Pain Med. 2020;45:249. [CrossRef]
  • Kim MH, Im YJ, Kil HK, Han SW, Joe YE, Lee JH. Impact of caudal block on postoperative complications in children undergoing tubularised incised plate urethroplasty for hypospadias repair: a retrospective cohort study. Anaesthesia. 2016;71:773-778. [CrossRef]
  • Zaidi RH, Casanova NF, Haydar B, Voepel-Lewis T, Wan JH. Urethrocutaneous fistula following hypospadias repair: regional anesthesia and other factors. Paediatr Anaesth. 2015;25:1144-1150. [CrossRef]
  • Braga LH, McGrath M, Farrohyar F. Dorsal penile bloc versus caudal epidural anesthesia effect on complications post-hypospadias repair: Dilemmas, damned dilemmas and statistics. J Pediatr Urol. 2020;16:708-711. [CrossRef]
  • Braga LH, Jegatheeswaran K, McGrath M, et al. Cause and Effect versus Confounding-Is There a True Association between Caudal Blocks and Tubularized Incised Plate Repair Complications? J Urol. 2017;197:845-851. [CrossRef]
  • Taicher BM, Routh JC, Eck JB, Ross SS, Wiener JS, Ross AK. The association between caudal anesthesia and increased risk of postoperative surgical complications in boys undergoing hypospadias repair. Paediatr Anaesth. 2017;27:688-694. [CrossRef]
  • Kreysing L, Höhne C. A retrospective evaluation of fistula formation in children undergoing hypospadiasrepair and caudal anesthesia. Paediatr Anaesth. 2016;26:329- 330. [CrossRef]
  • Ngoo A, Borzi P, McBride CA, Patel B. Penile nerve block predicts higher revision surgery rate following distal hypospadias repair when compared with caudal epidural block: A consecutive cohort study. J Pediatr Urol. 2020;16:439.e1-439.e6. [CrossRef]
  • Saavedra-Belaunde JA, Soto-Aviles O, Jorge J, Escudero K, Vazquez-Cruz M, Perez-Brayfield M. Can regional anesthesia have an effect on surgical outcomes in patients undergoing distal hypospadias surgery? J Pediatr Urol. 2017;13:45.e1-45. e4. [CrossRef]
  • Goel P, Jain S, Baipai M, Khanna P, Jain V, Yadav DK. Does caudal analgesia increase the rates of urethrocutaneous fistula formation after hypospadias repair? Systematic review and meta-analysis. Indian J Urol. 2019;35:222-229. [CrossRef]
  • Soh CR, Ng SB, Lim SL. Dorsal penile nerve block. Paediatr Anaesth. 2003;13:329- 333. [CrossRef]
  • Ozen V, Yigit D. Caudal epidural block versus ultrasound-guided dorsal penile nerve block for pediatric distal hypospadias surgery: A prospective, observational study. J Pediatr Urol. 2020;16:438.e1438.e8. [CrossRef]
  • Zhu C, Wei R, Tong Y, Liu J, Song Z, Zhang S. Analgesic efficacy and impact of caudal block on surgical complications of hypospadias repair- a systematic review and meta-analysis. Reg Anesth Pain Med. 2019;44:259-267. [CrossRef]
  • Erol A, Tavlan A, Tuncer S, et al. Caudal anesthesia for minor subumbilical pediatric surgery: a comparison of levobupivacaine alone and levobupivacaine plus sufentanil. J Clin Anesth. 2008;20:442-446. [CrossRef]
  • Alizadeh F, Heydari SM, Nejadgashti R. Effectiveness of caudal epidural block on interaoperative blood loss during hypospadias repair: A randomized clinical trial. J Pediatr Urol. 2018;14:420.e1-420.e5. [CrossRef]
  • Baltogiannis DM, Charalabopoulos AK, Giannakopoulos XK, Giannakis DJ, Sofikitis NV. Penile erection during transurethral surgery. J Androl. 2006;27:376-380. [CrossRef]
  • Dokter EM, Mouës CM, Rooij IALMV, Biezen JJ van der. Complications after hypospadias correction: Prognostic factors and impact on final clinical outcome. Eur J Pediatr Surg. 2018;28:200-206. [CrossRef]
  • Splinter WM, Kim J, Kim AM, Harrison MA. Effect of anesthesia for hypospadias repair on perioperative complications. Paediatr Anaesth. 2019;29:760- 767. [CrossRef]
  • Adler AC, Chandrakantan A, Lee AD, Koh CJ, Janzen NK, Austin PF. Effect of caudal vs. penile block on the incidence of hypospadias complications following primary repairs: A retrospective cohort study. J Urol. 2021;205:1454-1459. [CrossRef]
  • Tugtepe H, Thomas DT, Kandirici A, Yener S, Dagli Tolga. Should we routinely test for chordee in patients with distal hypospadias? Eur J Pediatr Surg. 2015;25:195-198. [CrossRef]
  • Chhibber AK, Perkins FM, Rabinowitz R, Vogt AW, Hulbert WC. Penile block timing for postoperative analgesia of hypospadias repair in children. J Urol. 1997;158:1156- 1159. [CrossRef]
  • Snodgrass W, Villanueva C, Bush NC. Duration of follow-up to diagnose hypospadias urethroplasty complications. J Pediatr Urol. 2014;10:208-211. [CrossRef]
  • Faasse MA, Liu DB. Early vs. late-presenting urethroplasty complications after hypospadias repair- A retrospective analysis of patient follow-up. J Pediatr Urol. 2017;13:354.e1-354.e5. [CrossRef]
  • Metzelder ML, Kuebler JF, Glueer S, Suempelmann R, Ure BM, Petersen C. Penile block is associated with less urinary retention than caudal anesthesia in distal hypospadias repair in children. World J Urol. 2010;28:87-91. [CrossRef]
  • Snodgrass WT, Bush N, Cost N. Tubularized incised plate hypospadias repair for distal hypospadias. J Pediatr Urol. 2010;6:408-413. [CrossRef
Balkan Medical Journal-Cover
  • ISSN: 2146-3123
  • Başlangıç: 2015
  • Yayıncı: Erkan Mor
Sayıdaki Diğer Makaleler

Circ_0010235 Regulates HOXA10 Expression to Promote Malignant Phenotypes and Radioresistance in Non-small Cell Lung Cancer Cells Via Decoying miR-588

Hongyan ZHU, Wenshu YANG, Qingping CHENG, Shuai YANG

FLOT2 Promotes the Proliferation and Epithelial-mesenchymal Transition of Cervical Cancer by Activating the MEK/ERK1/2 Pathway

Yang Lİ, Shulan DOU

The Clinicopathological Characteristics of Pure and Mixed Invasive Micropapillary Breast Carcinomas: A Single Center Experience

Gülnihan Eren KUPİK, Kadri ALTUNDAĞ

Effects of Caudal and Penile Blocks on the Complication Rates of Hypospadias Repair

Ahsen Karagözlü AKGÜL, Halil TUĞTEPE, Arzu CANMEMİŞ, Ali EYVAZOV, Hilal HÜREL, Gürsu KİYAN, Tümay UMUROĞLU

Cost-of-disease of Heart Failure in Turkey: A Delphi Panel-based Analysis of Direct and Indirect Costs

Yüksel ÇAVUŞOĞLU, Hakan ALTAY, Dursun ARAS, Ahmet TEMİZHAN, Ahmet ÇELİK, Fatih Sinan ERTAŞ, Barış KILIÇASLAN, Sanem NALBANTGİL, Dilek URAL, Özlem YILDIRIMTÜRK, Mehmet Birhan YILMAZ

Hiccups Caused by Fitz-Hugh-Curtis Syndrome

Toshimasa YAMAGUCHİ

Cytomegalovirus Reactivation in Critically-ill COVID-19 Patients

Leyla TALAN, Neslihan Defne ALTINTAŞ, İrem Akdemir KALKAN, Fügen YÖRÜK

Characterization of 31 Patients with Riboflavin-Responsive Multiple acyl-CoA Dehydrogenase Deficiency

Jinru ZHANG, Yaye WANG, Yue WU, Xueqin SONG, Guang Jİ, Jingzhe HAN, Lixia MA

Serum Expression Levels of Certain miRNAs in Predicting Diagnosis, Prognosis, and Response to Chemotherapy in Malignant Pleural Mesothelioma

Muzaffer METİNTAŞ, Güntülü AK, Filiz BOĞAR, Selma METİNTAŞ, Cansu ÖZBAYER

A Rare Adverse Event after CoronaVac Administration: Neutropenia in a Kidney Transplant Recipient

Ayşe Serra ARTAN, Nurana GÜLLER, Aydın TÜRKMEN, Erol DEMİR