The study was on the SARS-CoV-2 pandemic in Nigeria and the impact on age and sex distributions. The analysis of this work was based on the data generated on confirmed, discharged, deaths, and active cases by the Nigeria Center for Disease Control (NCDC) between February and June 2020. The data as of June 2020, revealed that the death cases was 506, while the confirmed was 19808. The confirmed cases for the states followed this order: Lagos > FCT > Kano > Rivers down to Kogi the least figure recorded, while death rates followed this order: Lagos > FCT > Edo > Oyo down to Adamawa the least figure. The sex distributions of SARS-CoV-2 of the confirmed cases showed that male had a higher number in comparison to female, while in the age distributions, it was observed that the age groups most affected were: 21 - 30, 31 - 40, 41 - 50, 51 - 60 for both male and female. About 4% (male) and 5% (female) were recorded for ages less than 10 years old. The age and sex distributions observed in COVID-19 vulnerability depict the importance of a better understanding of the impact of age and sex on incidence and case fatality of the virus and to tailor treatment according to age and sex.