An Overview of Vital Tooth Bleaching

An Overview of Vital Tooth Bleaching

Bleaching of tooth discolorations became more attractive with the increasing importance of aesthetics. Therefore, in recent years, bleaching treatment has become one of the fastest-growing parts of aesthetic dentistry. Bleaching can generally be carried out with hydrogen peroxide or carbamide peroxide both at-home and in-office. Bleaching systems have been offered to the public as a more conservative and economical approach for improving dental appearance. However, the dental profession should maintain high ethical standards and not recommend cosmetic adjustments to the tooth color to suit the patient's demand. Therefore, in this article, vital tooth whitening applications are discussed.

___

  • de Abreu, D. R., Sasaki, R. T., Amaral, F. L. B., Flório, F. M., Basting, R. T. (2011). Effect of home-use and in-office bleaching agents containing hydrogen peroxide associated with amorphous calcium phosphate on enamel microhardness and surface roughness. Journal of Esthetic and Restorative Dentistry, 23(3), 158–168.
  • Akpata, E. S. (2001). Occurrence and Management of Dental Fluorosis. International Dental Journal, 51(5), 325–333.
  • Alqahtani, M. Q. (2014). Tooth-bleaching procedures and their controversial effects: a literature review. Saudi Dental Journal, 26(2), 33–46.
  • Arens, D. (1989). The role of bleaching in esthetics. Dental Clinics of North America, 33(2), 319–336.
  • Aschheim, K. W. (2014). Esthetic dentistry: a clinical approach to techniques and materials, Third Edition. Elsevier Health Sciences.
  • Atkinson, C. B. (1892). Fancies and some facts. The Dental Cosmos, 34(12), 968-972.
  • Attin, T., Betke, H., Schippan, F., Wiegand, A. (2007). Potential of fluoridated carbamide peroxide gels to support post-bleaching enamel re-hardening. Journal of Dentistry, 35(9), 755–759.
  • Azer, S. S., Hague, A. L., Johnston, W. M. (2011). Effect of bleaching on tooth discolouration from food colourant in vitro. Journal of Dentistry, 39(Suppl 3), 52–56.
  • Azer, S. S., Machado, C., Sanchez, E., Rashid, R. (2009). Effect of home bleaching systems on enamel nanohardness and elastic modulus. Journal of Dentistry, 37(3), 185–190.
  • Barghi, N. (1998). Making a clinical decision for vital tooth bleaching: at-home or in-office? Compendium Of Continuing Education In Dentistry, 19(8), 831–838.
  • Bartlett, D. (2001). Bleaching discoloured teeth. Dental Update, 28(1), 14–18.
  • Basting, R. T., Rodrigues, A. L., Serra, M. C. (2003). The effects of seven carbamide peroxide bleaching agents on enamel microhardness over time. Journal of the American Dental Association, 134(10), 1335–1342.
  • Basting, R. T, Fernandez, C. F., Ambrosano, C. M. B., Campos, I. T. (2005). Effects of a 10% carbamide peroxide bleaching agent on roughness and microhardness of packable composite resins. Journal of Esthetic and Restorative Dentistry, 17(4), 256–262.
  • Berger, S. B., Coelho, A. S., Oliveira, V. A., Cavalli, V., Giannini, M. (2008). Enamel susceptibility to red wine staining after 35% hydrogen peroxide bleaching. Journal of Applied Oral Science, 16(3), 201–204.
  • Bernardon, J. K., Sartori, N., Ballarin, A., Perdigão, J., Lopes, G. C., Baratieri, L. N. (2010). Clinical performance of vital bleaching techniques. Operative Dentistry, 35(1), 3–10.
  • BoeiraI, G. F., SalasI, M. M. S., AraújoI, D. C., MasottiI, A. S., CorreaI, M. B., Demarco, F. F. (2016). Factors influencing dental appearance satisfaction in adolescents: a cross-sectional study conducted in southern brazil. Brazilian Journal of Oral Sciences, 15(1), 8–15.
  • Bowles, W. H., and Ugwuneri Z. (1987). Pulp chamber penetration by hydrogen peroxide following vital bleaching procedures. Journal of Endodontics, 13(8), 375–377.
  • Browning, W. D., Chan, D. C., Myers, M. L., Brackett, W. W., Brackett, M. G., Pashley, D. H. (2008). Comparison of traditional and low sensitivity whiteners. Operative Dentistry, 33(4), 379–385.
  • Buchalla, W., Attin, T. (2007). External bleaching therapy with activation by heat, light or laser-a systematic review. Dental Materials, 23(5), 586–596.
  • Bulut, H., Turkun, M., Kaya, A. D. (2006). Effect of an antioxidizing agent on the shear bond strength of brackets bonded to bleached human enamel. American Journal of Orthodontics and Dentofacial Orthopedics, 129(2), 266–272.
  • Carey, C. M. (2014). Tooth whitening: what we now know. Journal of Evidence-Based Dental Practice, 14(suppl.), 70–76.
  • Cavalli, V., Giannini M., Carvalho, R. M. (2004). Effect of carbamide peroxide bleaching agents on tensile strength of human enamel. Dental Materials, 20(8), 733–739.
  • Chen, H. P., Chang, C. H., Liu, J. K., Chuang, S. F., Yang, J. Y. (2008). Effect of fluoride containing bleaching agents on enamel surface properties. Journal of Dentistry, 36(9), 718–725.
  • Cho, S. D., Bulpakdi, P., Matis, B. A., Platt, J. A. (2009). Effect of bleaching on fracture toughness of resin composites. Operative Dentistry, 34(6), 703–708.
  • Christensen, G. J. and Christensen, R. P. (1995). Home use bleaching survey. CRA Newsletter 19(1).
  • Chuang, S. F, Chen, H. P., Chang, C. H., Liu, J. K. (2009). Effect of fluoridated carbamide peroxide gels on enamel microtensile bond strength. European Journal of Oral Sciences, 117(4), 435–441.
  • Cullen, D. R., Nelson, J. A, Sandrik, J. L. (1993). Peroxide bleaches: effect on tensile strength of composite resins. The Journal of Prosthetic Dentistry, 69(3), 247–249.
  • Cvitko, E., Denehy, G. E., Swift, E. J., Pires, J. A. F. (1991). Bond strength of composite resin to enamel bleached with carbamide peroxide. Journal of Esthetic and Restorative Dentistry, 3(3), 100–102.
  • Demarco, F. F., Meireles, S. S., Sarmento, H. R., Dantas, R. V., Botero, T., Tarquinio, S. B. (2011). Erosion and abrasion on dental structures undergoing at-home bleaching. clinical. Cosmetic and Investigational Dentistry, 3, 45–52.
  • Demarco, F. F., Meireles, S. S., Masotti, A. S. (2009). Over-the-counter whitening agents: a concise review. Brazilian Oral Research, 23(suppl. 1), 64–70.
  • Donly, K. J., Segura, A., Henson, T., Barker, M. L., Gerlach, R. W. 2007. Randomized controlled trial of professional at-home tooth whitening in teenagers. General Dentistry, 55(7), 669–674.
  • Downs, J., Convissar, R. A., Anagnostaki, E., Sun, G. (2011). Principles and practice of laser dentistry. In Principles and Practice of Laser Dentistry, Missouri, 151.
  • Duckworth, R. M. (2006). The teeth and their environment : Physical, Chemical and Biochemical Influences. Karger.
  • Durner, J., Stojanovic, M., Urcan, E., Spahl, W., Haertel, U., Hickel, R., Reichl, F. X. (2011). Effect of hydrogen peroxide on the three-dimensional polymer network in composites. Dental Materials, 27(6), 573–580.
  • Dutra, A., Frary, J, Wise, R. (2004). Higher-order needs drive new growth in mature consumer markets. Journal of Business Strategy, 25(5), 26–34.
  • El-Murr, J., Ruel, D, St-Georges, A. J. (2011). Effects of external bleaching on restorative materials: a review. Journal of the Canadian Dental Association, 77, 59.
  • Elfallah, H. M., Bertassoni, L. E., Charadram, N., Rathsam, C., Swain, M. V. (2015). Effect of tooth bleaching agents on protein content and mechanical properties of dental enamel. Acta Biomaterialia, 20, 120–128.
  • Fay, R. M., Servos, T., Powers, J. M. (1999). Color of restorative materials after staining and bleaching. Operative Dentistry, 24(5), 292–296.
  • Feinman, R. A., Madray, G., Yarborough, D. (1991). Chemical, optical, and physiologic mechanisms of bleaching products: a review. Practical Periodontics and Aesthetic Dentistry, 3(2), 32–36.
  • Feinman, R. A., Goldstein, R. E., Garber, D. A. (1987). Bleaching teeth. Quintessence Pub. Co.
  • Fisher, G. (1911). The Bleaching of discolored teeth with H2O2. The Dental Cosmos, 53, 246–247.
  • Freedman, G., Gerlach, R. W, Greenwall, L. H. (2012). Contemporary esthetic dentistry. In Contemporary Esthetic Dentistry, Mosby, 341–404.
  • Freire, A., Souza, E. M., de Menezes Caldas, D. B., Rosa, E. A., Bordin, C. F., de Carvalho, R. M., Vieira, S. (2009). Reaction kinetics of sodium ascorbate and dental bleaching gel. Journal of Dentistry, 37(12), 932–936.
  • Garber, D. A. (1997). Dentist-monitored bleaching: a discussion of combination and laser bleaching. Journal of the American Dental Association, 128(Suppl.), 26–30.
  • García-Godoy, F., Dodge, W. W., Donohue, M., O’Quinn, J. A. (1993). Composite resin bond strength after enamel bleaching. Operative Dentistry, 18(4), 144–147.
  • Garcia-Lopez, M., Martinez-Blanco, M, Martinez-Mir, I., Palop, V. (2001). Amoxycillin-clavulanic acid-related tooth discoloration in children. Pediatrics, 108(3), 819.
  • Gerlach, R. W., Barker, M. L., Karpinia, K., Magnusson, I. (2009). Single site meta-analysis of 6% hydrogen peroxide whitening strip effectiveness and safety over 2 weeks. Journal of Dentistry, 37(5), 360–365.
  • Gerlach, R. W. and Zhou, X. (2001). Vital bleaching with whitening strips: summary of clinical research on effectiveness and tolerability. Journal of Contemporary Dental Practice, 2(3), 1–15.
  • Gerlach, R. W., Zhou, X., Mcclanahan, S. F. (2002). Comparative response of whitening strips to a low peroxide and potassium nitrate bleaching gel. American Journal of Dentistry, 15(spec. iss. 1), 19–23.
  • Gerlach, R. W. and Barker, M. L. (2004). Professional vital bleaching using a thin and concentrated peroxide gel on whitening strips: an integrated clinical summary. The Journal of Contemporary Dental Practice, 5(1), 1–17.
  • Giniger, M., MacDonald, J., Ziemba, S., Felix, H. (2005). The clinical perfrmance of professionally dispensed bleaching gel with added amorphous calcium phosphate. Journal of the American Dental Association, 136(3), 383–392.
  • Gokay, O., Mujdeci, A., Algin, E. (2005). In vitro peroxide penetration into the pulp chamber from newer bleaching products. International Endodontic Journal, 38(8), 516–520.
  • Goo, D. H., Kwon, T. Y., Nam, S. H., Kim, H. J., Kim, K. H., Kim, Y. J. (2004). The efficiency of 10% carbamide peroxide gel on dental enamel. Dental Materials Journal, 23(4), 522–527.
  • Greenwall, L., Fredman, G., Gordan, V. V. (2001). Bleaching techniques in restorative dentistry: an illustrated guide. Martin Dunitz.
  • Hanks, C. T., Fat, J. C., Corcoran, J. F., Wataha, J. C. (1993). Cytotoxicity and dentin permeability of carbamide peroxide and hydrogen peroxide vital bleaching materials, in vitro. Journal of Dental Research, 72(5), 931–938.
  • Hannig, C., Zech, R., Henze, E., Dorr-Tolui, R., Attin, T. (2003). Determination of peroxides in saliva-kinetics of peroxide release into saliva during home-bleaching with Whitestrips® and Vivastyle®. Archives of Oral Biology, 48(8), 559–566.
  • Hannig, C., Duong, S., Becker, K., Brunner, E., Kahler, E., Attin, T. (2007). Effect of bleaching on subsurface micro-hardness of composite and a polyacid modified composite. Dental Materials, 23(2), 198–203.
  • Hansen, J. R., Frick, K. J, Walker, M. P. (2014). Effect of 35% sodium ascorbate treatment on microtensile bond strength after nonvital bleaching. Journal of Endodontics, 40(10), 1668–1670.
  • Hatanaka, G. R., de Oliveira Abi-Rached, F., de Almeida-Júnior, A. A., dos Santos Cruz, C. A. (2013). Effect of carbamide peroxide bleaching gel on composite resin flexural strength and microhardness. Brazilian Dental Journal, 24(3), 263–266.
  • Haywood, V. B. and Heymann, H. O. (1989). Nightguard vital bleaching. Quintessence international, 20(3), 173–176.
  • Haywood, V. B., Heymann, H. O. (1991). Nightguard vital bleaching: how safe is it? Quintessence International, 22(7), 515–523.
  • Haywood, V. B. (1991). Overview and Status of Mouthguard Bleaching. Journal of Esthetic and Restorative Dentistry, 3(5), 157–161.
  • Haywood, V. B. (1992). History, safety, and effectiveness of current bleaching techniques and applications of the nightguard vital bleaching technique. Quintessence international, 23(7), 471–488.
  • Haywood, V. B. (1996). Achieving, maintaining, and recovering successful tooth bleaching. Journal of Esthetic and Restorative Dentistry, 8(6), 31–38.
  • Haywood, V. B. (2000). Current status of nightguard vital bleaching. Compendium of Continuing Education in Dentistry, 28(suppl.), 10–17.
  • Haywood, V. B. (2000). A comparison of at-home and inoffice bleaching. Dent Today, 19(4), 44–53.
  • Haywood, V. B, Caughman, W. F., Frazier, K. B., Myers, M. L. (2001). Tray delivery of potassium nitrate-fluoride to reduce bleaching sensitivity. Quintessence International, 32(2), 105–109.
  • Haywood, V. B. (2001). Fundamentals of operative dentistry: a contemporary approach. Eds. Submit, J.B., Robbins, J.W., and Schwart, R.S. Chicago: Quintessence Pub. Co., 401–426.
  • He, L. B., Shao, M. Y., Tan, K., Xu, X., Li, J. Y. (2012). The effects of light on bleaching and tooth sensitivity during in-office vital bleaching: a systematic review and meta-analysis. Journal of Dentistry, 40(8), 644–653.
  • Joiner, A., Pickles, M. J., Matheson, J. R., Weader, E., Noblet, L., Huntington, E. (2002). Whitening toothpastes: effects on tooth stain and enamel. International Dental Journal, 52(S5), 424–430.
  • Joiner, A. (2004). Tooth colour: a review of the literature. Journal of Dentistry, 32(suppl.), 3–12.
  • Joiner, A., Philpotts, C. J., Ashcroft, A. T., Laucello, M., Salvaderi, A. (2008). In vitro cleaning, abrasion and fluoride efficacy of a new silica based whitening toothpaste containing blue covarine. Journal of Dentistry, 36(suppl. 1), 32–37.
  • Joiner, A., Thakker, G. (2004). In vitro evaluation of a novel 6% hydrogen peroxide tooth whitening product. Journal of Dentistry, 32(suppl.), 19–25.
  • Joshi, S. (2016). An overview of vital teeth bleaching. Journal of Interdisciplinary Dentistry, 6(1), 3–13.
  • Kashima-Tanaka, M., Tsujimoto, Y., Kawamoto, K., Senda, N., Ito, K., Yamazaki, M. (2003). Generation of free radicals and/or active oxygen by light or laser irradiation of hydrogen peroxide or sodium hypochlorite. Journal of Endodontics, 29(2), 141–143.
  • Kihn, P. W. (2007). Vital tooth whitening. Dental Clinics of North America, 51(2), 319–331.
  • Kishta-Derani, M., Neiva, G., Yaman, P, Dennison, J. (2007). In vitro evaluation of tooth-color change using four paint-on tooth whiteners. Operative Dentistry, 32(4), 394–398.
  • Kugel, G., Aboushala, A., Zhou, X., Gerlach, R. W. (2002). Daily use of whitening strips on tetracycline-stained teeth: comparative results after 2 months. Compendium of Continuing Education In Dentistry, 23(1A), 29–34.
  • Lai, S. C., Tay, F. R., Cheung, G. S., Mak, Y. F., Carvalho, R. M., Wei, S. H., Toledano, M., Osorio, R., Pashley, D. H. (2002). Reversal of compromised bonding in bleached enamel. Journal of Dental Research, 81(7), 477–481.
  • Lee, C. Q., Cobb, C. M., Zargartalebi, F., Hu, N. Effect of bleaching on microhardness, morphology, and color of enamel. General Dentistry, 43(2), 158–160.
  • Lee, K. H., Kim, H. I., Kim, K. H., Kwon, Y. H. (2006). Mineral loss from bovine enamel by a 30% hydrogen peroxide solution. Journal of Oral Rehabilitation, 33(3), 229–233.
  • Lima, D. A., Silva, A. L., Aguiar, F. H., Liporoni, P. C., Munin, E., Ambrosano, G. M., Lovadino, J. R. (2008). In vitro assessment of the effectiveness of whitening dentifrices for the removal of extrinsic tooth stains. Brazilian Oral Research, 22(2), 106–111.
  • Leonard, R. R. H., Garland, G. E., Eagle, J. C., Caplan, D. J. (2002). Safety issues when using a 16% carbamide peroxide whitening solution. Journal of Esthetic and Restorative Dentistry, 14(6), 358–367.
  • Li, Q., Yu, H., Wang, Y. (2009). Colour and surface analysis of carbamide peroxide bleaching effects on the dental restorative materials in situ. Journal of Dentistry, 37(5), 348–356.
  • Li, Y., Greenwall, L. (2013). Safety issues of tooth whitening using peroxide-based materials. British Dental Journal, 215(1), 29–34.
  • Li, Y. (2003). Effect of light application on an in-office bleaching gel. Journal of Dental Research, 82.
  • Lo, E. C. M., Wong, A. H. H., McGrath, C. (2007). A randomized controlled trial of home tooth-whitening products. American Journal of Dentistry, 20(5), 315–318.
  • Luk, K., Tam, L., Hubert, M. (2004). Effect of light energy on peroxide tooth bleaching. Journal of the American Dental Association, 135(2), 194–201.
  • Markowitz, K. (2010). Pretty painful: why does tooth bleaching hurt? Medical Hypotheses, 74(5), 835–840.
  • Matis, B. A., Cochran, M. A., Eckert, G. J., Matis, J. I. (2007). In vivo study of two carbamide peroxide gels with different desensitizing agents. Operative Dentistry, 32(6), 549–555.
  • Matis, B. A., Mousa, H. N., Cochran, M. A., Eckert, G. J. (2000). Clinical evaluation of bleaching agents of different concentrations. Quintessence International, 31(5), 303–310.
  • McEvoy, S. A. (1995). Removing Intrinsic stains from vital teeth by microabrasion and bleaching. journal of Esthetic and Restorative Dentistry, 7(3), 104–109.
  • McGuckin, R. S., Babin, J. F., Meyer, B. J. (1992). Alterations in human enamel surface morphology following vital bleaching. The Journal of Prosthetic Dentistry, 68(5), 754–760.
  • Meireles, S. S., da Silva Dos Santos, I., Bona, A. D., Demarco, F. F. (2009). A double-blind randomized controlled clinical trial of 10 percent versus 16 percent carbamide peroxide tooth-bleaching agents. Journal of the American Dental Association, 140(9), 1109–1117.
  • Nathoo, S. A. (1997). The chemistry and mechanisms of extrinsic and intrinsic discoloration. Journal of the American Dental Association, 128(suppl. 4), 6–10.
  • Odioso, L. L., Gibb, R. D., Gerlach, R. W. (2000). Impact of demographic, behavioral, and dental care utilization parameters on tooth color and personal satisfaction. Compendium Of Continuing Education In Dentistry, 29(suppl.), 35–41.
  • Ontiveros, J. C. (2011). In-office vital bleaching with adjunct light. Dental Clinics of North America, 55(2), 241–253.
  • de Paula, E. A., Nava, J. A., Rosso, C., Benazzi, C. M., Fernandes, K. T., Kossatz, S., Loguercio, A. D., Reis, A. (2015). In-office bleaching with a two- and seven-day intervals between clinical sessions: a randomized clinical trial on tooth sensitivity. Journal of Dentistry, 43(4), 424–429.
  • Petersson, L. G. (2013). The role of fluoride in the preventive management of dentin hypersensitivity and root caries. Clinical Oral Investigations, 17(suppl.1), 63–71.
  • Pinto, C. F., de Oliveira, R., Cavalli, V., Giannini, M. (2004). Peroxide bleaching agent effects on enamel surface microhardness, roughness and morphology. Brazilian Oral Research, 18(4), 306–311.
  • Poulsen, S, Errboe, M., Mevil, Y. L., Glenny, A. (2006). Potassium containing toothpastes for dentine hypersensitivity. Cochrane Database of Systematic Reviews, 19(3), CD001476.
  • Rodrigues, J. A., Oliveira, G. P. F, Amaral, C. M. (2007). Effect of thickener agents on dental enamel microhardness submitted to at-home bleaching. Brazilian Oral Research, 21(2), 170–175.
  • Rosenstiel, S. F., Gegauff, A. G., Johnston, W. M. (1996). Randomized clinical trial of the efficacy and safety of a home bleaching procedure. Quintessence International, 27(6), 413–424.
  • Sagel, P. A., Odioso, L. L., McMillan, D. A., Gerlach, R. W. (2000). Vital tooth whitening with a novel hydrogen peroxide strip system: design, kinetics, and clinical response. Compendium Of Continuing Education In Dentistry, 29(suppl.), 10–15.
  • Sánchez, A. R., Rogers, R. S., Sheridan, P. J. (2004). Tetracycline and other tetracycline-derivative staining of the teeth and oral cavity. International Journal of Dermatology, 43(10), 709–715.
  • Sherwood, I. (2010). Fluorosis varied treatment options. Journal of Conservative Dentistry, 13(1), 47.
  • da Silva Machado J., Cândido, M. S., Sundfeld, R. H., de Alexandre, R. S., Cardoso, J. D., Sundefeld, M. L. (2007). The influence of time interval between bleaching and enamel bonding. Journal of Esthetic and Restorative Dentistry, 19(2), 111–118.
  • Strassler, H. E. (2006). Vital tooth bleaching: an update. Continuing Education Insert, 4, 1–8
  • Şi̇şmanoğlu, S., Gümüştaş, B., Efes, B. G. (2013) The impact of fluoride or ozone gas before vital tooth bleaching on enamel surface roughness. European Oral Research, 47(1) , 1–7.
  • Soares, D. G., Basso, F. G., Scheffel, D. S., Hebling, J., de Souza Costa, C. A. (2015). Responses of human dental pulp cells after application of a low-concentration bleaching gel to enamel. Archives of Oral Biology, 60(9), 1428–1436.
  • Costa, C. A., Riehl, H., Kina, J. F., Sacono, N. T., Hebling, J. (2010). Human pulp responses to in-office tooth bleaching. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology, 109(4), 59–64.
  • Sulieman, M. (2004). An overview of bleaching techniques: I. history, chemistry, safety and legal aspects. Dental Update, 31(10), 612–616.
  • Sulieman, M. (2005). An overview of bleaching techniques: 2. night guard vital bleaching and non-vital bleaching. Dental Update, 32(1), 39–46.
  • Sulieman, M., Addy, M., MacDonald, E., Rees, J. S. (2005). The bleaching depth of a 35% hydrogen peroxide based in-office product: a study in vitro. Journal of Dentistry, 33(1), 33–40.
  • Sulieman, M., Addy, M., Rees, J. S. (2003). Development and evaluation of a method in vitro to study the effectiveness of tooth bleaching. Journal of Dentistry, 31(6), 415–422.
  • Sulieman, M. (2008). An overview of tooth-bleaching techniques: chemistry, safety and efficacy. Periodontology 2000, 48(1), 148–169.
  • Swift, E. J. and Perdigão, J. (1998). Effects of bleaching on teeth and restorations. Compendium Of Continuing Education In Dentistry, 19(8), 815–820
  • Tam, L. (1999). Clinical trial of three 10% carbamide peroxide bleaching products. Journal (Canadian Dental Association), 65(4), 201–205.
  • Tam, L. (2001). Effect of potassium nitrate and fluoride on carbamide peroxide bleaching. Quintessence International, 32(10), 766–770.
  • Tarbet, W. J., Buckner, A., Stark, M. M., Fratarcangelo, P. A., Augsburger, R. (1981). The pulpal effects of brushing with a 5 percent potassium nitrate paste used for desensitization. Oral Surgery, Oral Medicine, Oral Pathology, 51(6), 600–602.
  • Tay, L. Y., Kose, C., Loguercio, A. D., Reis, A. (2009). assessing the effect of a desensitizing agent used before in-office tooth bleaching. Journal of the American Dental Association, 140(10), 1245–1251.
  • Thylstrup, A., Fejerskov, O. (1978). Clinical appearance of dental fluorosis in permanent teeth in relation to histologic changes. Community Dentistry and Oral Epidemiology, 6(6), 315–328.
  • Titley, K. C., Torneck, C. D., Smith, D. C., Chernecky, R., Adibfar, A. (1991). Scanning electron microscopy observations on the penetration and structure of resin tags in bleached and unbleached bovine enamel. Journal of Endodontics, 17(2), 72–75.
  • Titley, K. C, Torneck, C. D., Smith, D. C. (1988). The effect of concentrated hydrogen peroxide solutions on the surface morphology of human tooth enamel. Journal of Endodontics, 14(2), 69–74.
  • Toko, T., Hisamitsu, H. (1993). Shear bond strength of composite resin to unbleached and bleached human dentine. Asian Journal of Aesthetic Dentistry, 1(1), 33–36.
  • Torres, C. R., Batista, G. R., César, P. D., Barcellos, D. C., Pucci, C. R., Borges, A. B. (2009). Influence of the quantity of coloring agent in bleaching gels activated with led/laser appliances on bleaching efficiency. The European Journal of Esthetic Dentistry, 4(2), 178–186.
  • Turkun, M., Kaya, A. D. (2004). Effect of 10% sodium ascorbate on the shear bond strength of composite resin to bleached bovine enamel. Journal of Oral Rehabilitation, 31(12), 1184–1191.
  • Turkun, M., Celik, E. U., Kaya, A. D., Arici, M. (2009). Can the hydrogel form of sodium ascorbate be used to reverse compromised bond strength after bleaching? The Journal of Adhesive Dentistry, 11(1), 35–40.
  • Unlu, N., Cobankara, F. K., Ozer, F. (2008). Effect of elapsed time following bleaching on the shear bond strength of composite resin to enamel. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 84B(2), 363–368.
  • Ushigome, T., Takemoto, S., Hattori, M., Yoshinari, M., Kawada, E., Oda, Y. (2009). Influence of peroxide treatment on bovine enamel surface - cross-sectional analysis. Dental Materials Journal, 28(3), 315–323.
  • Vilhena, K. F. B., Nogueira, B. C. L., Fagundes, N. C. F., Loretto, S. C., Angelica, R. S., Lima, R. R., Silva E., Souza M. H. J. (2019). Dental enamel bleached for a prolonged and excessive time: morphological. Plos One, 14(4), e0214948.
  • Viscio, D., Gaffar, A., Fakhry-Smith, S., Xu, T. (2000). Present and future technologies of tooth whitening. Compendium of Continuing Education In Dentistry, 28(suppl.), 36–43.
  • Vohra, F. A., Kasah K. (2014). Influence of bleaching and antioxidant agent on microtensile bond strength of resin based composite to enamel. Saudi Journal for Dental Research, 5(1), 29–33.
  • Walsh, L. J. (2000). Safety issues relating to the use of hydrogen peroxide in dentistry. Australian Dental Journal, 45(4), 257–269.
  • Watts, A., Addy, M. (2001). Tooth Discolouration and staining: a review of the literature. British Dental Journal, 190(6), 309–316.
  • Yap, A. U. J., Wattanapayungkul, P. (2002). Effects of in-office tooth whiteners on hardness of tooth-colored restoratives. Operative Dentistry, 27(2), 137–141.
  • Yu, H., Pan, X., Lin, Y., Li, Q., Hussain, M., Wang, Y. (2009). Effects of carbamide peroxide on the staining susceptibility of tooth-colored restorative materials. Operative Dentistry, 34(1), 72–82.
  • Yu, H., Li, Q., Lin, Y., Buchalla, W., Wang, Y. (2010). Influence of carbamide peroxide on the flexural strength of tooth-colored restorative materials: an in vitro study at different environmental temperatures. Operative Dentistry, 35(3), 300–307.
  • Yu, H., Li, Q., Cheng, H., Wang, Y. (2011). The effects of temperature and bleaching gels on the properties of tooth-colored restorative materials. Journal of Prosthetic Dentistry, 105(2), 100–107.
  • Yu, H., Li, Q., Hussain, M., Wang, Y. (2008). Effects of bleaching gels on the surface microhardness of tooth-colored restorative materials in situ. Journal of Dentistry, 36(4), 261–267.
  • Yu, H., Zhang, C. Y., Cheng, S. L., Cheng, H. (2015). Effects of bleaching agents on dental restorative materials: a review of the literature and recommendation to dental practitioners and researchers. Journal of Dental Sciences, 10(4), 345–351.
  • Zantner, C., Derdilopoulou, F., Martus, P., Kielbassa, A. M. (2006). Randomized clinical trial on the efficacy of 2 over-the-counter whitening systems. Quintessence International, 37(9), 695–706.