Köpeklerde Kornea Yaralarının Onarımında Organik Doku Yapıştırıcısı Fibrin Adeziv'in Etkileri

Organik doku yapıştırıcısı Fibrin Adezivin köpek korneal yara iyileşmesi üzerine etkisi araştırıldı. Köpek modelindeoluşturulan 2, 5, 7, 11 mm uzunluğundaki kesiler üzerine 0.02- 0.05 ml Fibrin Adeziv uygulandı. Kontrol gruplarındakonjunktival flap, dikiş, kontakt lens ve tarsorafi uygulamaları yapıldı. Korneal yara iyileşmesinin 2 aylık izleme süresince klinik,bu süre sonunda histolojik özellikleri araştırıldı. Fibrin Adezivin basit dikiş uygulanan kesilerle benzer özellikte yara iyileşmesisağladığı belirlendi. Fibrin Adezivin dikiş konulamayan olgularda dikiş uygulamalarına alternatif oluşturabileceği saptandı.

Effects of Organic Tissue Sealant Fibrin Adhesive in Corneal Wounds Healing of Dogs

: The effects of Fibrin Adhesive (Tisseel- tissue adhesive) in corneal wounds were investigated in dogs. A 0.02- 0.05 mlTisseel was applied onto the incision area (2, 5, 7, 11 mm length) in dog model. Conjunctival flapping, suture applicati ons,contact lens placement and tharsorraphy were performed in the control groups. To evaluate the corneal wound healing, theclinical controls were conducted during 2 months and after this period histologi cal examinations were carried out. It wasdetected that the corneal wound healing with Tisseel was si milar with simple suture pattern. It was determined that Tisseelcould be an alternative method in cases not suitable for sutures.

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