Gültekin KADI, Muhammed Enes DURAK, Begüm ÖKTEM, Ahmet DEMİRCAN, Ayfer KELEŞ

Phytocontact Dermatitis Due to Ranunculus Kotschyi Boiss : Adverse Effect for Artralgia Treatment

There has been a great variety of cases relating to herbal therapies across the world. Some of them do not have any risks, whereas some others may result in severe complications. Ranunculus kotschyi (buttercup) is a wild annual plant belonging to Ranunculaceae family. Many phytodermatitis cases associated with the members of the Ranunculaceae family have been reported. In this case report, we present a 60-year-old female patient suffering from irritant phytodermatitis secondary to topical use of Ranunculus kotschyi.

Keywords:

Ranunculus Kotschyi, Contact, Ranunculus, Irritant Contact Dermatitis, Phytodermatitis.,

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1. Gönül M, Gül U, Cakmak SK, Kiliç S. Unconventional medicine in dermatology outpatients in Turkey. Int J Dermatol. 2009;48(6):639-44.
2. Polat M, Oztas P, Yalcin B, Tamer E, Gur G, Alli N. Contact dermatitis due to Allivum sativum and Ranunculus illyricus: two cases. Contact Dermatitis. 2007;57(4):279-80.
3. Akbulut S, Semur H, Kose O, Ozhasenekler A, Celiktas M, Basbug M, et al. Phytocontact dermatitis due to Ranunculus arvensis mimicking burn injury: report of three cases and literature review. Int J Emerg Med. 2011;4(1):7.
4. Ozkol HU, Calka O, Akdeniz N, Pinar SM. Phytodermatitis in eastern Turkey: a retrospective, observational study. Dermatitis. 2014;25(3):140-6.
5. Calka O, Akdeniz N, Özkol HU, Karadag AS, Behçet L. Irritant contact dermatitis caused by Ranunculus kotschyi Boiss in 6 cases. Contact Dermatitis. 2011;64(3):174-6.
6. Metin A, Calka O, Behçet L, Yildirim E. Phytodermatitis from Ranunculus damascenus. Contact Dermatitis. 2001;44(3):183.
7. Hao D-C, He C-N, Shen J, Xiao P-G. Anticancer Chemodiversity of Ranunculaceae Medicinal Plants: Molecular Mechanisms and Functions. Curr Genomics. 2017;18(1):39-59.
8. Erbay MŞ, Anıl S, Melikoğlu G. Plants used as painkiller in folk medicine in Turkey–III: Rheumatic pain. Marmara Pharm J 2018;22(2):133-41.
9. Li RZ, Ji XJ. [The cytotoxicity and action mechanism of ranunculin in vitro]. Yao Xue Xue Bao. 1993;28(5):326-31.
10. Burbach JP. [The blistering effect of buttercups]. Ned Tijdschr Geneeskd. 1963;107:1128-30.