Relation of serum immunoglobulin E level with coronary artery disease and SYNTAX score

Aim: Inflammation has a significant role in the pathogenesis of atherosclerosis and allergic inflammation has also an important impact on atherosclerosis progression. In this study, we investigated whether the serum IgE levels are associated with coronary artery disease (CAD) and SYNTAX score as a parameter for severity of the disease. Methods: A total of 171 patients who were planned coronary angiography were recruited consecutively into this study. The patients who had a diagnosis of asthma, autoimmune diseases, allergic dermatitis, history of allergic diseases, parasitic infections, malignancy, severe renal failure (estimated glomerular filtration rate

Serum immunglobulin E seviyesi ile koroner arter hastalığı ve SYNTAX skoru arasındaki ilişki

Amaç: İnflamasyon aterosklerozun patogenezinde önemli bir role sahiptir. Alerjik inflamasyonun da aterosklerozun ilerlemesinde önemli bir etkisi mevcuttur. Çalışmamızda IgE düzeyi ile koroner arter hastalığı (KAH) arasında ilişki olup olmadığına baktık. Ayrıca ek olarak IgE ile KAH ciddiyetini gösteren SYNTAX skoru arasındaki ilişkiyi de değerlendirdik. Metot: Çalışmaya ardışık olarak 171 tane koroner angiografi planlanan hasta alındı. Astım, oto immun hastalık, alerjik dermatit, alerji öyküsü, parazit infestasyonu, kanser, ciddi böbrek yetmezliği (glomeriüler filtrasyon hızı

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