Abdullah ŞENLİKCİ, Koray KOŞMAZ, Abdullah DURHAN, Marlen SÜLEYMAN, Yusuf Murat BAG, Mevlüt Recep PEKCİCİ, Mehmet ŞENEŞ, İlknur ALKAN KUŞABBİ, Ozlem TANAS ISIKCI, Yılmaz ÜNAL, Sema HÜCÜMENOĞLU

Rektal Yoldan Uygulanan Red-Ginsengin Kolorektal Anastomoz İyileşmesinde Etkisi Var mıdır? Deneysel Çalışma

Amaç: Red-ginsengin kolon anastomozu iyileşmesindeki olası etkilerini değerlendirmek. Metot: Grup 1’de (sham) laparotomi ve kolonik mobilizasyon yapıldı. Diğer 2 grupta (grup 2+3) kolonik transeksiyon ve anastomoz yapıldı. Grup 2 (kontrol)’de tüm ratlara 10 gün boyunca rektal yoldan 2 ml saline verildi. Grup 3 (ilaç grubu)’de tüm ratlara 10 gün boyunca 2,5 gr/kg ml red ginseng ekstresi verildi. Sonuçlar: Sham grubundaki ratlar en yüksek patlama basıncına sahipti ve red ginseng grubundaki ratlar kontrol grubuna göre daha yüksek patlama basıncına sahipti (p

Anahtar Kelimeler:

Red-ginseng, anastomoz, antioksidan, rat

Does Rectal Application of Red-Ginseng have an Effect on Colorectal Anastomosis Healing? An Experimental Study

Aim: To evaluate the possible effects of red-ginseng on colon anastomosis healing in an experimental rat model. Methods: In Group 1 (sham), laparotomy and colonic mobilization were performed. Colonic transection and anastomosis were performed to Groups 2 and 3. In Group 2 (control), 2 ml of saline was administered rectally to all rats for 10 days. Group 3 (drug group) rats were given 2.5 gr/kg ml red ginseng extract rectally for 10 days. Results: The rats in the sham group had the highest bursting pressure and the rats in the red ginseng group had higher bursting pressure than in the control group (p

Keywords:

Red-ginseng, anastomosis, antioxidant, rat,

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