The importance of clinical and histopathological correlation in the diagnosis of skin diseases: An eleven years’ experience

Aim: In this study, we aimed to evaluate the correlation of preliminary diagnoses and definitive histopathological diagnoses in skin diseases.Material and Methods: The study included the patients having at least one skin biopsy in a tertiary center for last eleven years. The clinical preliminary diagnoses were classified into different groups and the correlation between the first three preliminary diagnoses and the definitive histopathological diagnoses was investigated.Results: The number of the biopsies performed in young and adults was higher than the number of biopsies performed in children and older patients. The most common cutaneous conditions biopsied were tumors, papulosquamous diseases and nevi. The rate of the correct clinical diagnosis including one of the first three preliminary diagnoses was 58.8%. The same rate was found to be 79.1% with the cooperation of the dermatologists and pathologists.Conclusion: Our study showed that the repetitive biopsies and strong cooperation of dermatologists and pathologists may increase the rate of precise histopathological diagnosis.

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