Tayibe BAL, Mehmet ÇABALAK, Burçin ÖZER, Mehmet Selim ÇÖMEZ, Yusuf ÖNLEN

The high rate of Candida parapsilosis candidemia among non-burn patients with polytrauma in the surgical intensive care units of a university hospital

Aim: Candidemia is a life-threatening infection that has been reported to be associated with poorer outcomes in trauma patients.The present study aimed to investigate the epidemiology of candidemia in non-burn patients with polytrauma.Material and Methods: We conducted a retrospective, single-center, observational study of polytrauma patients with candidemiaadmitted to the surgical intensive care units of a university hospital in Turkey between 2013 and 2017 on.Results: The incidence of candidemia was 127 episodes per 1000 intensive care unit admissions in polytrauma patients. Nonalbicans Candida species accounted for 75.5% of all candidemia episodes. C. parapsilosis (51.05%) was the predominant species,followed by C. albicans (24.52%) and C. tropicalis (12.21%). The highest crude mortality rate (72%) was observed in patients with C.parapsilosis candidemia. In multivariate analyses, who had undergone prior gastrointestinal surgery were 7.1 times more likely tohave C. parapsilosis candidemia than those with other strains.Conclusion: Our study, remarkable, demonstrated a high incidence of Candidemia had in polytrauma patients, and non-albicansCandida species were the most frequently isolated candida species. According to our study findings, a prior history of gastrointestinalsurgery may help predict C. parapsilosis, as the causative agent of candidemia in polytrauma patients. However, since our study wasobservational and limited to such a small number of patients, the results obtained should be applied with caution.

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