The association of abo blood groups and serum ferritin levels with telogen effluvium in women

The association of abo blood groups and serum ferritin levels with telogen effluvium in women

Aim: Telogen effluvium(TE) in women is a common problem in dermatology and has multiple etiologic causes. Low iron storescan be a possible contributing factor in TE. Although etiopathogenesis is not fully understood, many studies show remarkableassociations between various diseases and ABO blood groups. Genomewide association studies have reported alleles in the ABO locus to be associated with ferritin levels. We had done this study with TE patients to detect serum ferritin levels and to find this relation between blood groups.Material and Methods: Healthy people and patients with TE were included in this study. A total of 103 females who have telogen effluvium and 125 controls were included.Results: ABO blood group and Rhesus factor distribution in patients with TE and distribution of healthy donors were similar. There haven’t any significant association between ferritin levels and blood groups in TE patients.Conclusion: There are many different causes in TE etiology, for this reason in our opinion, ferritin levels and other laboratory tests must be done. We conclude that there was no evocation between ABO blood groups, Rhesus factor and ferritin levels in TE, but this is the first study that can show this relationship and can be important for new studies which will be carried out in other centers with wider series.

___

  • Benyamin B, Esko T, Ried JS, Radhakrishnan A, Vermeulen SH, Traglia M, et al. Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis. Nat Commun 2014;5:4926.
  • Wu KJ, Polack A, Dalla-Favera R. Coordinated regulation of iron-controlling genes, H-ferritin and IRP2, by c-MYC. Science 1999;283(5402):676-9.
  • Cole CR, Grant FK, Swaby-Ellis ED, Smith JL, Jacques A, Northrop-Clewes CA, et al. Zinc and iron deficiency and their interrelations in low-income African American and Hispanic children in Atlanta. Am J Clin Nutr 2010;91(4):1027-34.
  • Sinclair R. There is no clear association between low serum ferritin and chronic diffuse telogen hair loss. Br J Dermatol 2002;147(5):982-4.
  • Klein HG, Anstee DJ. ABO, Lewis and P groups and Ii antigens. In: Klein HG, Anstee DJ, eds. Mollison’s blood transfusion in clinical medicine. Oxford: Blackwell Publishing Ltd 2005:114-62.
  • Garratty G. Blood groups and disease: a historical perspective. Transfus Med Rev 2000;14(4):291-301.
  • Garratty G. Relationship of blood groups to disease: do blood group antigens have a biological role? Rev Med Inst Mex Seguro Soc. 2005;43(Suppl 1):113-21.
  • Rigas AS, Berkfors AA, Pedersen OB, Sørensen E, Nielsen KR, Larsen MH. et al. Reduced ferritin levels in individuals with non-O blood group: results from the Danish Blood Donor Study. Transfusion 2017;57(12):2914-9.
  • Ozyurt K, Oztürk P, Gül M, Benderli YC, Cölgeçen E, Inci R. ABO blood groups, Rhesus factor, and Behçet’s disease. Acta Dermatovenerol Alp Pannonica Adriat 2013;22(3):63-4.
  • İslamoğlu ZGK, Unal M. Is there an association of ABO blood groups and rhesus factor with alopecia areata? J Cosmet Dermatol 2018;15.
  • Mouhari-Toure A, Saka B, Kombaté K, Akakpo S, Egbohou P, Tchangaï-Walla K. et al. Is there an association between keloids and blood groups. ISRN Dermatol 2012;2012:750908.
  • Eiermann TH, Vejbaesya S, Prestel H. Association and linkage of human leukocyte antigens with psoriasis – revisited. Infusionstherapie-und Transfusionsmedizin 2002;29(6):326-30.
  • Valikhani M, Kavand S, Toosi S, Kavand G, Ghiasi M. ABO Blood groups, Rhesus factor and pemphigus. Indian J Dermatol 2007:52(4):176-8.
  • de Giorgi V, Grazzini M, Gori A, Alfaioli B, Rossari S, Crocetti E, et al. ABO blood group and risk of cutaneous malignant melanoma. Eur J Cancer Prev 2011;20(2):121-2.
  • Donbak L, Rencuzogullari E, Topaktas M, Kayrın L. Detection of some blood group (ABO, RH-D) and serum protein (HP, a1-AT, TF) polymorphisms in Antakya Province, Turkey. J Med Res 2002;20(3):109-13.
  • Kantor J, Kessler LJ, Brooks DG, Cotsarelis G. Decreased serum ferritin is associated with alopecia in women. J Invest Dermatol 2003;121(5):985-8.
  • Olsen EA, Reed KB, Cacchio PB, Caudill L. Iron deficiency in female pattern hair loss, chronic telogen effluvium, and control groups. J Am Acad Dermatol 2010;63(6):991-9.
  • Bregy A, Trueb RM. No association between serum ferritin levels >10 microg/l and hair loss activity in women. Dermatology 2008;217(1):1-6.
  • Rasheed H, Mahgoub D, Hegazy R, El-Komy M, Abdel Hay R, Hamid M.A, et al. Serum ferritin and vitamin d in female hair loss: do they play a role?. Skin Pharmacol Physiol 2013;26(2):101-7.
  • Hard S: Non-anemic iron deficiency as an etiologic factor in diffuse loss of hair of the scalp in women. Acta Derm Venereol 1963;43:562-9.
  • Sinclair R. Diffuse hair loss. Int J Dermatol 1999;38:1-18.
  • Trueb RM. Diffuse hair loss. In: Blume-Peytavi U, Tosti A, Whiting DA, Trueb R, editors. Hair growth and disorders, 1st editon. Berlin: Springer; 2008. p. 259-72.
  • Dinh QQ, Sinclair R. Female pattern hair loss: current treatment concepts. Clin Interv Aging 2007;2(2):189-99.
  • Shashikant M. Telogen Effluvium: A Review. J Clin Diagn Res 2015;9(9):WE01-WE03.
Annals of Medical Research-Cover
  • Yayın Aralığı: Aylık
  • Yayıncı: İnönü Üniversitesi Tıp Fakültesi
Sayıdaki Diğer Makaleler

Is digital addiction a reason for obesity?

Gülsen MERAL

The effect of surgeon’s fatigue on early term patency and complications of arteriovenous fistulas: A prospective cohort study

Hakan YABANOGLU, Sedat YILDIRIM, Tevfik AVCİ, Cağla BALİ, İlker Murat ARER

The role of histopathologic alterations of gallbladder wall in conversion cholecystectomy

Ayşe Bahar CEYRAN, Suleyman ORMAN

Assessment of risk factors on morbidity and mortality in patients undergoing percutaneous endoscopic gastrostomy

Yakup TOMAK, Mehmet AZİRET, Kerem KARAMAN, Yeşim AKDENİZ, Fehmi ÇELEBİ, Hakan YIRGIN, Metin ERCAN, Volkan OTER, Necattin FIRAT, Tuğçe EBİLOĞLU

When is free air a sign of complication on abdominal plain radiography after laparotomy in pediatric patients?

Mehmet DEMİRCAN, Harika GÖZÜKARA BAG, Kubilay GÜRÜNLÜOĞLU, Ahmet SİGİRCİ, Aytaç TAŞCİ

Determination of optic nerve sheath diameter variability with age in pediatric groups and comparison of increased intracranial pressure and optic nerve sheath diameter in pediatric patients with head trauma

Mustafa AVCI, Sevim YILDIZ, Alper Burak YAGAR, Yasemin KARAMAN, Nalan KOZACI

Use of the neutrophil to lymphocyte ratio compare crp for the early prediction of acute pancreatitis severity?

Burak Veli ÜLGER, Edip Erdal YILMAZ, Ahmet TURKOĞLU, Zülfü ARİKANOĞLU, Enver AY, Ömer USLUKAYA, Zübeyir BOZDAĞ, Metehan GÜMÜŞ, Yilmaz ZENGIN

Duodenal fistula after laparoscopic cholecystectomy

Mehmet SARAC, Serhat DOGAN

An anatomic overview to “manspreading” campaign

Mustafa CANBOLAT, Davut OZBAG, Deniz SENOL, Furkan CEVİRGEN

Abdominal wall endometriosis after caesarean section; single center experience

Arif EMRE, Ahmet AYKAS