Surgery for tethered cord syndrome: when and how?

Surgery for tethered cord syndrome: when and how?

Tethered cord syndrome (TCS) is a clinical condition presented with neurological and/or urological signs and findings. Increased hypoxic stress in the spinal cord secondary to traction or stretching is the pathophysiological mechanism of TCS. It is usually observed in childhood but adult cases were also reported. Its diagnosis and treatment are always challenging. Magnetic resonance imaging, electrophysiological and urodynamic studies are the main diagnostic tools for TCS. This syndrome may be primary or secondary to previous surgeries such as myelomeningocele. Asymptomatic patients with low conus medullaris and thick filum terminale are always questionable for surgical treatment. On the other hand, symptomatic patients with normal radiological imaging are critical for surgical decision. Surgical treatment involves correction of the spinal pathologies and release of the spinal cord by cutting the filum terminale. Time of surgery and technical nuances are still in debate among neurosurgeons. Neurological andurological outcomes of the patients usually depend on these factors. Timing of surgery and surgical technique need to be clarified based on the recent clinical studies. This review will focus on the time and technique of TCS surgery. Firstly, a brief description of TCS will be provided, then an extensive view on the surgical treatment of TCS will be performed.

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  • Samuels R, McGirt MJ, Attenello FJ, et al. Incidence of symptomatic retethering after surgical management of pediatric tethered cord syndrome with or without duraplasty. Childs Nerv Syst. 2009;25:1085-9.
  • Ohe N, Futamura A, Kawada R, et al. Secondary tethered cord syndrome in spinal dysraphism. Childs Nerv Syst. 2000;16:457-61.
  • Colak A, Pollack IF, Albright AL. Recurrent tethering: a common long-term problem after lipomyelomeningocele repair. Pediatr Neurosurg. 1998;29:184-90.
  • Ostling LR, Bierbrauer KS, Kuntz C 4th. Outcome, reoperation, and complications in 99 consecutive children operated for tight or fatty filum. World Neurosurg. 2012;77:187-91.
  • Kestle JR. Retethering after filum cutting. World Neurosurg. 2012;77:82.
  • Vassilyadi M, Tataryn Z, Merziotis M. Retethering in children after sectioning of the filum terminale. Pediatr Neurosurg. 2012;48:335-41.
  • Ogiwara H, Lyszczarz A, Alden TD, et al. Retethering of transected fatty filum terminales. J Neurosurg Pediatr. 2011;7:42-6.
  • Yong RL, Habrock-Bach T, Vaughan M, et al. Symptomatic retethering of the spinal cord after section of a tight filum terminale. Neurosurgery. 2011;68:1594-601.
  • Wang AC, Than KD, Etame AB, et al. Impact of anesthesia on transcranial electric motor evoked potential monitoring during spine surgery: a review of the literature. Neurosurg Focus 2009;27:E7.
  • Beyazova M, Zinnuroglu M, Emmez H, et al. Intraoperative neurophysiological monitoring during surgery for tethered cord syndrome. Turk Neurosurg 2010;20:480-4.
  • Yılmaz A, Özdemir B, Altaş K, et al. Intraoperative neurophysiologic monitoring in patients with tethered cord syndrome: clinical experience in thirty patients. The Medical Bulletin of Şişli Etfal Hospital. 2017;51:43-7.
  • Maurya VP, Rajappa M, Wadwekar V, et al. Tethered cord syndrome-A study of the short-term effects of surgical detethering on markers of neuronal injury and electrophysiologic parameters. World Neurosurg. 2016;94:239-47.
  • Pusat S, Kural C, Solmaz I, et al. Comparison of electrophysiological outcomes of tethered cord syndrome and spinal intradural tumors: A retrospective clinical study. Turk Neurosurg. 2017;27:797-803.
  • Gao J, Kong X, Li Z, et al. Surgical treatments on adult tethered cord syndrome: A retrospective study. Medicine (Baltimore). 2016;95:e5454.
  • Lin W, Xu H, Duan G, et al. Spine-shortening osteotomy for patients with tethered cord syndrome: a systematic review and metaanalysis. Neurol Res. 2018;40:340-63.
  • Grande AW, Maher PC, Morgan CJ, et al. Vertebral column subtraction osteotomy for recurrent tethered cord syndrome in adults: a cadaveric study. J Neurosurg Spine. 2006;4:478-4.
  • Kokubun S, Ozawa H, Aizawa T, et al. Spine-shortening osteotomy for patients with tethered cord syndrome caused by lipomyelomeningocele. J Neurosurg Spine. 2011;15:21-7.
  • Magrassi L, Chiaranda I, Minelli M, et al. Total endoscopic approach to the cauda in a patient with a tight filum. Minim Invasive Neurosurg. 2008;51:350-3
  • Di X. Endoscopic spinal tethered cord release: operative technique. Childs Nerv Syst. 2009;25:577-81.
  • Veronesi V, Sacco C, Mastronicola C, et al. Transhiatal approach to filum terminale extrenum sectioning in adult patient with tethered cord syndrome: case report. Oper Neurosurg (Hagerstown). 2018;15:E1-E4.
  • Telfeian AE, Punsoni M, Hofstetter CP. Minimally invasive endoscopic spinal cord untethering: case report. J Spine Surg. 2017;3:278-82.
  • Hayashi T, Kimiwada T, Kohama M, et al. Minimally invasive surgical approach to filum lipoma. Neurol Med Chir (Tokyo). 2018;58;132-7.
  • Selcuki M, Mete M, Barutcuoglu M, et al. Tethered cord syndrome in adults: experience of 56 patients. Turk Neurosurg. 2015;25:922-9.
  • Seki T, Hida K, Yano S, et al. Surgical outcome of children and adolescents with tethered cord syndrome. Asian Spine J. 2016;10:940-4.
  • Abdallah A, Emel E, Abdallah BG, et al. Factors affecting the surgical outcomes of tethered cord syndrome in adults: a retrospective study. Neurosurg Rev. 2018;41:229-39.
  • Rendeli C, Ausili E, Tabacco F, et al. Urodynamic evaluation in children with lipomeningocele: timing for neurosurgery, spinal cord tethering and follow-up. J Urol. 2007;177:2319-24.
  • Cornette L, Verpoorten C, Lagae L, et al. Tethered cord syndrome in occult spinal dysraphism: timing and outcome of surgical release. Neurology. 1998;50:1761-5.
  • Mclone DG, La Marca F. The Tethered spinal cord; diagnosis, significance, and management. Semin Pediatric Neurology 1997;4:192-208.
  • Nakanishi K, Tanaka N, Kamei N, et al. Use of prone position magnetic resonance imaging for detecting the terminal filum in patients with occult tethered cord syndrome. J Neurosurg Spine. 2013;18:76–84.
  • Lew SM, Kothbauer KF. Tethered cord syndrome: an updated review. Pediatr Neurosurg. 2007;43:236-48.
  • Alatas I, Demirci H, Canaz H, et al. The role of urodynamic studies in the diagnosis and treatment of patients with spina bifida. Asian J Neurosurg. 2015;10:83-6.
  • Steinbok P, MacNeily AE, Hengel AR, et al. Filum section for urinary incontinence in children with occult tethered cord syndrome: A randomized, controlled pilot study. J Urol. 2016;195:1183-8.
  • Geyik M, Geyik S, Şen H, et al. Urodynamic outcomes of detethering in children: experience with 46 pediatric patients. Childs Nerv Syst. 2016;32:1079-84.
  • Izci Y, Gonul M, Gonul E. The diagnostic value of skin lesions in split cord malformations. J Clin Neurosci. 2007;14:860-3.
  • Hayward R. Tethered cord syndrome. Br J Neurosurgery 1998;12:75-6.
  • Pang D, Wilberger JE Jr. Tethered cord syndrome in adults. J Neurosurg. 1982;57:32-47.
  • Pang D. Tethered cord syndrome. Wilkins RH, Rengachery SS edition, Neurosurgery, Volume 3 New York: McGraw-Hill, 1996:3465-96
  • Park ST, Kanev PM, Henegar MM, Kaufman BA. Occult spinal dysraphism. Youmans JR edition. Neurological Surgery, Volume 2, Philedelphia: WB Saunders, 1996:873-89
  • Iskandar BJ, Oakes WJ. Occult spinal dysraphism. Albright AL, Pollack IF, Adelson PD edition. Principles and Practice of Pediatric Neurosurgery, New York: Thieme; 1999:321-351
  • Kural C, Solmaz I, Tehli O, et al. Evaluation and management of lumbosacral myelomeningoceles in children. Eurasian J Med. 2015;47:174-8.
  • Kural C, Pusat S, Solmaz I, et al. The evaluation and surgical treatment of sacral dermal sinus tracts in children. Gulhane Med J 2011;53:284-89.
  • Kural C, Solmaz I, Pusat S, et al. Surgical technique for split cord malformations: pitfalls and solution pathways. Gulhane Med J. 2013;55:77-83.
  • Gluncic V, Turner M, Burrowes D, et al. Concurrent Chiari decompression and spinal cord untethering in children: feasibility in a small case series. Acta Neurochir. 2011;153:109-14.
  • Milhorat TH, Bolognese PA, Nishikawa M, et al: Association of Chiari malformation type I and tethered cord syndrome: preliminary results of sectioning filum terminale. Surg Neurol. 2009;72:20-35.
  • Kacar Y, Mehtiyev R, Ramikhanov Z, et al. Tethered cord syndrome: 5 year clinical experiences and surgical results. J Turgut Ozal Med Cent. 2018;25:80-5.
  • Selçuki M. Tethered cord syndrome. In: Baykaner, Erşahin, Mutluer, Özek, Pediatric Neurosurgery. Turkish Neurosurgical Society Publications. 2014. p. 253-8.
  • Solmaz I, Izci Y, Albayrak B, et al. Tethered cord syndrome in childhood: special emphasis on the surgical technique and review of the literature with our experience. Turk Neurosurg 2011;21:516- 21.
  • Daszkiewicz P, Barszcz S, Roszkowski M, et al. Maryniak A. Tethered cord syndrome in children-impact of surgical treatment on functional neurological and urological outcome. Neurol Neurochir Pol. 2007;41:427-35.
  • Yamada S, Won DJ, Yamada SM. Pathophysiology of tethered cord syndrome: correlation with symptomatology. Neurosurg Focus. 2004;16:E6.
  • Hoffman HJ, Hendrick EB, Humphreys RP. The tethered spinal cord: its protean manifestations, diagnosis and surgical correction. Childs Brain. 1976;2:145-55.
  • Khoury AE, Hendrick EB, McLorie GA, et al. Occult spinal dysraphism: clinical and urodynamic outcome after division of the filum terminale. J Urol. 1990;144:426-9.
  • Hou Y, Sun J, Shi J, et al. Clinical evaluation of an innovative operative procedure in the treatment of the tethered cord syndrome. Spine J. 2018;18998-1004.
Annals of Medical Research-Cover
  • Yayın Aralığı: Aylık
  • Yayıncı: İnönü Üniversitesi Tıp Fakültesi
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