Incidental ectopic pancreas during upper gastrointestinal endoscopy

Incidental ectopic pancreas during upper gastrointestinal endoscopy

Aim: Ectopic pancreas is a rare developmental anomaly which is detected incidentally in general. Frequently, it is an incidentalfinding and can be detected in various regions of gastrointestinal system. It can be readily recognized by its crater-like appearance at gastric antrum adjacent to pylori during upper gastrointestinal endoscopy. Here, we presented characteristics of cases with ectopic pancreas which was detected incidentally during upper gastrointestinal endoscopy performed for other reasons. Material and Methods: We retrospectively reviewed upper gastrointestinal endoscopy evaluations performed in our endoscopy unit between January 2012 and December 2015. Age, gender, endoscopy indication, endoscopic findings, and histopathological findings, if available, were recorded in all patients with ectopic pancreas. Results: Overall, 9850 patients underwent upper gastrointestinal endoscopy between January 2012 and December 2015; of these, findings compatible to ectopic pancreas were observed in 14 patients (0.14%). Those were 4 males (28.5%) and 10 females (71.5%). Mean age was 49 years (29-69 years) in these patients. Ectopic pancreas tissue was detected at gastric antrum of all patients. Mean size was 8.5 mm (5-15 mm) in lesions detected. Histopathological examination was performed in 9 patients (64.2%) and chronic gastritis was observed in all of these patients. Conclusion: Ectopic pancreas should be kept in mind in the differential diagnosis of several gastrointestinal submucosal lesions although it is rarely seen.

___

  • Zhang Y, Huang Q, Zhu LH, et al. Endoscopic excavation for gastric heterotopic pancreas: an analysis of 42 cases from a tertiary center. Wien Klin Wochenschr 2014;126:509-14.
  • Yüksel M, Kacar S, Akpınar MY, Saygılı F, Kayhan MA, Dişibeyaz S, et al. Endosonogragphic features of lesions suggesting gastric ectopic pancreas: experience of a single tertiary center. Turkish journal of medical sciences 2017;47(1):313-7.
  • Bromberg SH, Neto C, Borges AF, et al. Pancreatic heterotopias: clinicopathological analysis of 18 patients. Rev Col Bras Cir 2010;37:413-9.
  • Rubbia-Brandt L, Huber O, Hadengue A, et al. An unusual case of gastric heterotopic pancreas. JOP 2004;5:484-7.
  • Ryu DY, Kim GH, Park DY, et al. Endoscopic removal of gastric ectopic pancreas: An initial experience with endoscopic submucosal dissection. World J Gastroenterol 2010;16:4589-93.
  • Agale SV, Agale VG, Zode RR, et al. Heterotopic pancreas involving stomach and duodenum. J Assoc Physicians India 2009;57:653-4.
  • Armstrong CP, King PM, Dixon JM, et al. The clinical significance of heterotopic pancreas in the gastrointestinal tract. Br J Surg 1981;68:384-7.
  • Jun SY, Son D, Kim MJ, et al. Heterotopic Pancreas of the Gastrointestinal Tract and Associated Precursor and Cancerous Lesions: Systematic Pathologic Studies of 165 Cases. Am J Surg Pathol 2017;41:833-48.
  • Zhang Y, Sun X, Gold JS, et al. Heterotopic pancreas: a clinicopathological study of 184 cases from a single high-volume medical center in China. Hum Pathol 2016;55:135-42.
  • Hsia CY, Wu CW, Lui WY. Heterotopic pancreas: a difficult diagnosis. J Clin Gastroenterol 1999;28:144-7.
  • Dolan RV, ReMine WH, Dockerty MB. The fate of heterotopic pancreatic tissue. A study of 212 cases. Arch Surg 1974;109(6):762-5.
  • Tanaka K, Tsunoda T, Eto T, et al. Diagnosis and management of heterotopic pancreas. Int Surg 1993;78:32-5.
Annals of Medical Research-Cover
  • Yayın Aralığı: Aylık
  • Yayıncı: İnönü Üniversitesi Tıp Fakültesi