Ismail KOYUNCU, Ahmet GUZELCİCEK, Abdullah SOLMAZ, Busra CEVİRGEN

Investıgation of thiol-dısulfıde balance ın chıldren wıth pneumonıa

Aim: We aimed to investigate the thiol-disulfide balance, role of oxidative stress in pneumonia and role of measurement of thiol as a new biological marker for the diagnosis of pneumonia in children with pneumonia who admitted to pediatric emergency service and general pediatric polyclinic.Material and Methods: In our study, patients between 6 months and 4 years of age, who admitted to the Pediatric Emergency Department and Pediatric Policlinic of between January 2017 and February 2018 with a diagnosis of community-acquired pneumonia, were evaluated prospectively. A total of 90 patients were included in the study, including 45 patients and 45 healthy children in the same age group. These patients were examined for age, gender, symptoms and physical examination findings, native thiol, total thiol and disulfide values.Results: There was no significant difference between the patient and control groups in terms of gender. Statistically significant difference was observed between native thiol, total thiol and disulfide values between patient and control group (p

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