Evaluation of morphometry in extrahepatic bile ducts in preoperative and postoperative periods in diabetic and non - diabetic patients with cholelithiasis
Evaluation of morphometry in extrahepatic bile ducts in preoperative and postoperative periods in diabetic and non - diabetic patients with cholelithiasis
Aim: The aim of this study was to find out and to compare the effect of cholecystectomy performed due to gallstone on theextrahepatic bile ducts morphometry in diabetic and non-diabetic patients.Material and Methods: Three groups consisting of a total of 120 individuals. Diabetic patients with cholelithiasis (DC group) consistedof 40 person, non-diabetic patients with cholelithiasis (N-DC group) consisted of 40 person and healthy group (H group) consistedof 40 person. Laparoscopic cholecystectomy was performed on individuals with cholelithiasis.DHC (ductus hepaticus communis) diameter was measured below hepatic canal bifurcation from mucosa to mucosa byultrasonography. The measurements were conducted in preoperative period and in the third and sixth postoperative months.Results: There were no significant differences between DC and N-DC groups in terms of DHC diameters in preoperative period andpostoperative third and sixth months. In both DC and N-DC groups, DHC diameters in postoperative third and sixth months werefound to show a small but statistically significant increase.Conclusion: This study showed a small but statistically significant dilatation in DHC following cholecystectomy. In addition, nostatistically significant difference was found between DC and N-DC groups in terms of post- cholecystectomy DHC dilatation.
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- 1. Portincasa P, Ciaula AD, Bonfrate L, et al. Therapy of gallstone disease: What it was, what it is, what it will be. World J Gastrointest Pharmacol Ther 2012;3:7-20.
- 2. Stinton LM, Myers RP, Shaffer EA. Epidemiology of gallstones. Gastroenterol Clin N Am 2010;39:157-69.
- 3. Aerts R, Penninckx F. The burden of gallstone disease in Europe. Aliment Pharmacol Ther 2003;18:49-53. 4. Chowdhury AH, Lobo DN. Gallstones. Surgery (Oxford) 2011;29:610-7.
- 5. Akat AZ, Doğanay M, Koloğlu M, et al. Evaluation of 1000 laparoscopic cholecystectomies performed in one institution. T Klin J Med Sci 2002;22:133-41.
- 6. Memisogullari R, Taysi S, Bakan E, et al. Antioxidant status and lipid peroxidation in type II diabetes mellitus. Cell Biochem Funct 2003;21:291-6.
- 7. Memişoğulları R, Bakan E. Levels of ceruloplasmin, transferrin, and lipid peroxidation in the serum of patients with Type 2 diabetes mellitus. J Diabetes Complications 2004;18:193-7.
- 8. Hanbidge AE, Buckler PM, O’Malley ME, et al. From the RSNA refresher courses: imaging evaluation for acute pain in the right upper quadrant. Radiographics 2004;24:1117-35.
- 9. Berk RN, Cooperberg PL, Gold RP, et al. Radiography of the bile ducts: a symposium on the use of new modalities for diagnosis and treatment. Radiology 1982;145:1-9.
- 10. Targarona EM, Bendahan GE. Management of common bile duct stones: controversies and future perspectives. HPB(Oxford) 2004;6:140-3.
- 11. Valkovic P, Miletic D, Zelic M, et al. Dynamic changes in the common bile duct after laparoscopic cholecystectomy: a prospective longitudinal sonographic study. Ultraschall Med 2011;32:479-84.
- 12. Bruneton JN, Roux P, Fenart D, et al. Ultrasound evaluation of common bile duct size in normal adult patients and following cholecystectomy. A report of 750 cases. Eur J Radiol 1981;1:171-2.
- 13. Hunt DR, Scott AJ. Changes in bile duct diameter after cholecystectomy: a 5-year prospective study. Gastroenterology 1989;97:1485-8.
- 14. Parulekar SG. Ultrasound evaluation of common bile duct size. Radiology 1979;133:703-7.
- 15. Nakeeb A, Comuzzie AG, Martin L, et al. Gallstones: genetics versus enviroment. Ann Surg 2002;235:842- 9.
- 16. Arık MK, Türk N, Süner A. The incidence of metabolic syndrome in patients with operation for gallbladder. Medeniyet Med J 2010;25:158-63.
- 17. Williams K, Tchernof A, Hunt KJ, et al. Diabetes, abdominal adiposty, and atherogenic dyslipoproteinemia in women compared With men. Diabetes 2008;57:3289-96.
- 18. Liu CM, Hsu CT, Li CY, et al. A population-based cohort study of symptomatic gallstone disease in diabetic patients. World J Gastroenterol 2012;18:1652-9.
- 19. Saxena R, Sharma S, Dubey DC. Gallbladder disorder in type 2 diabetes mellitus cases. J Hum Ecol 2005;18:169-71.
- 20. Kaude JV. The width of the common bile duct in relation to age and stone disease. An ultrasonographic study. Eur J Radiol 1983;3:115-7.
- 21. Admassie D. Ultrasound assessment of common bile duct diameter in Tikur Anbessa Hospital, Addis Ababa, Ethiopia. Ethiop Med J 2008;46:391-5.
- 22. Reinus WR, Shady K, Lind M, et al. Ultrasound evaluation of the common duct in symptomatic and asymptomatic patients. Am J Gastroenterol 1992;87:489-92.
- 23. Edmunds R, Katz S, Garciano V, et al. The common duct after cholecystectomy. Interval report. Arch Surg 1971;103:79-81.
- 24. Horrow MM. Ultrasound of the extrahepatic bile duct: issues of size. Ultrasound Q 2010;26:67-74.
- 25. Gitelson S, Oppenheim D, Schwartz A. Size of the gallbladder in patients with diabetes mellitus. Diabetes 1969; 8:493-8.