Effects of sun dried organic apricot on serum total cholesterol, high density lipoprotein-cholesterol, triglyceride and total antioxidant capacity levels in rats

Effects of sun dried organic apricot on serum total cholesterol, high density lipoprotein-cholesterol, triglyceride and total antioxidant capacity levels in rats

Aim: In this study, we aimed to investigate the effects of sun dried organic apricot (SDOA) consumption on serum Total Cholesterol(TC), High-Density Lipoprotein-Cholesterol (HDL-C), Triglyceride (TG) and Total Antioxidant Capacity (TAC) levels in ratsMaterial and Methods: 120 males, 120 females rats were divided in to four groups according to their SDOA rates (1%, 2.5, 5 and 10)in chow (to be 24 rats in each gruop), and feding periods. At 120 days periods, the control group was fed with standard rat chow andthe others were fed with 1%, 2.5, 5 and 10 SDOA supplemented diet. At the end of 30th, 60th, 120th days; 8 rats which each genders/groups were sacrified by diethyl ether inhalation anesthesia, app. 8-10 mL blood samples were taken by intracardiac puncture andobtained serum samples were maintained at -20 ° C until the day of analysis.Results: After statistical analysis, TC levels of male rats; HDL-C levels of female rats increased in paralel with the feding process.Both TC and HDL-C levels of female rats were significantly higher than those of males. Although there were a significant decreasesin TG levels of both sexes at the end of feding periods, there was no significant difference between TG levels of both genders.Conclusion: It is thought that increases in TC and HDL-C levels are caused by rats affected by long-term feding periods. In addition,the significant difference between TC and HDL-C levels of male and female rats are thought to be affected by gender-specificreference values. The decrease in TG levels in both sexes is considered to be due to the increased energy needs of rats as well asthe effect of SDOA-added feeds.

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  • 1. Yılmaz I, Temel I, Gursoy S, et al. The effects of apricot on serum proteins and liver enzymes in rats. J Food Nutrit Res 2013;52:101-6.
  • 2. Ramazauskiene V, Petkeviciene J, Klumbiene J, et al. Diet and serum lipids: changes over socio-economic transition period in Lithuanian rural population. BMC Public Health 2011;11:447.
  • 3. FAO Statistical Yearbook 2013: World Food and Agriculture. http://www.fao.org/docrep/ 018/i3107e/ i3107e03.pdf
  • 4. Görünmezoğlu Ö. Kayısı ve İncir Meyvelerinin Antioksidan Kapasitelerinin Araştırılması. Adnan Menderes Üniversitesi, Yüksek Lisans Tezi. 2008, Aydın.
  • 5. Healthy Eating. Apricot Nutrition Facts. https://www. healthy-eating-centre.com/apricot-nutrition-facts. html (ET: 20-12-2018).
  • 6. Carter P, Gray LJ, Troughton J, et al. Fruit and vegetable intake and incidence of type 2 diabetes mellitus: systematic review and meta-analysis. BMJ 2010;341:4229.
  • 7. Scarborough P, Morgan RD, Webster P, et al. Differences in coronary heart disease, stroke and cancer mortality rats between England, Wales, Scotland and Northern Ireland: the role of diet and nutrition. BMJ 2011;263: 1-7.
  • 8. Joshipura KJ, Hu FB, Manson JE, et al. The effect of fruit and vegetable intake on risk for coronary heart disease. Annals of Internal Medicine 2001;134:1106- 14.
  • 9. Hartley L, Igbinedion E, Holmes J, et al. Increased consumption of fruit and vegetables for the primary prevention of cardio vascular diseases. Cochrane Database of Systematic Reviews 2013;6:CD009874.
  • 10. WHO Fruit and vegetables for health. Report of a joint FAO/WHO Workshop held 1–3 September 2004, Kobe/ Japan. Geneva, World Health Organization, 2005.
  • 11. Hall JN. Moore S, Harper SB, et al. Global variability in fruit and vegetable consumption. American Journal of Preventive Medicine 2009;36:402-9.
  • 12. Kahlon TS, Smith GE. Invitro binding of bile acids by bananas, peaches, pineapple, grapes, pears, apricots and nectarines. Food Chemistry 2007;101:1046-51.
  • 13. NCEP (National Cholesterol Education Program). Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adults (AdultTreatment Panel III) final report. Circulation 2002;106:3142-421.
  • 14. Erel O. A novel automated method to measure total antioxidant response against potent free radical reactions. Clin Biochem 2004;37:112-9.
  • 15. Unal RM. Kayısı Araştırma raporu. T.C. Fırat Kalkınma Ajansı, Malatya, 2010
  • 16. Munzuroglu O, Karatas, F, Geckil H. The vitamin and selenium contents of apricotfruit of different varieties cultivated in different geographical regions. Food Chem 2003;83:205-12.
  • 17. Vardi N, Parlakpinar H, Ozturk F, et al. Potent protective effect of apricot and beta-carotene on methotrexate induced intestinal oxidative damage in rats. Food
  • Chem Toxicol 2008;46:3015-22. 18. Parlakpinar H, Olmez E, Acet A, et al. Beneficial effects of apricot-feeding on myocardial ischemiareperfusion injury in rats. Food Chem Toxicol 2009; 47:802-808.
  • 19. Bhupathiraju SN, Tucker KL. Coronary heart disease prevention: Nutrients, foods, and dietary patterns. Clin Chim Acta 2011;412:1493-514.
  • 20. Dreher ML. Dietary Patterns and Whole Plant Foods in Aging and Disease. 2018. http://public.eblib.com/ choice/publicfullrecord.aspx?p=5295049 (ET: 31-12- 2018).
  • 21. Kutlu T, Durmaz G, Ates B, et al. Protective effect of dietary apricot kernel oil supplementation on cholesterol levels and antioxidant status of liver in hyper cholesteremic rats. J Food Agric & Environ 2009;7:61-5.
  • 22. Huang Z, Wang B, Eaves DH, et al. Total phenolics and antioxidant capacity of indigenous vegetables in the southeast United States: Alabama Collaboration for Cardiovascular Equality Project. Int J Food Sci Nutr 2007;18:29.
  • 23. Durmaz G, Alpaslan M. Antioxidant properties of roasted apricot (Prunus armeniacaL.) kernel. Food Chem 2007;100:1177-81.
  • 24. IDF (Internatioanl Diabetes Federation) The IDF Consensus Worldwide Definition of the Metabolic Syndrome. 2006. http://www.idf.org/webdata/docs/ IDF_Meta_def_final.pdf (ET: 20-12-2018).
  • 25. Altromin. Maintenance diet for rats and mice. https:// altromin. com/products /standarddiets /rats/1320 (ET: 31-12-2018).
  • 26. Mesomya W, Hengsawadi D, Cuptapun Y, Jittanoonta P and Thalang VN. Effect of Age on Serum Cholesterol and Triglyceride Levels in the Experimental Rats. Kasetsart J Nat Sci 2001;35:144-8.
  • 27. Kelly GS. Seasonal variations of selected cardiovascular risk factors. Altern Med Rev, 2005;10: 307-20.
  • 28. Kawano Y, David CE. Mechanisms of hepatic triglyceride accumulation in non-alcoholic fatty liver disease. Journal of Gastroenterology, 2013;4:434-41.
  • 29. Tomizawa M, Kawanabe Y, Shinozaki F, et al. Triglyceride is strongly associated with nonalcoholic fatty liver disease among markers of hyper lipidemia and diabetes. Biomedical Reports 2014;2:633-6.
  • 30. Nordestgaard BG, Varbo A. Triglycerides and cardiovascular disease. Lancet 2014;384:626-35.
Annals of Medical Research-Cover
  • Yayın Aralığı: Aylık
  • Yayıncı: İnönü Üniversitesi Tıp Fakültesi
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