Numan KARAARSLAN, Abdulkadir KARAARSLAN, Abdullah Talha SİMSEK, Bilgehan POTOGLU, İbrahim YİLMAZ, Mustafa DOGAN

A study on side effects of antibiotics used in the treatment of patients with head trauma and legal responsibility of clinicians in terms of the right to health

Aim: Patients with head trauma are routinely, and commonly treated with prophylactic antibiotics, which may also be used for thetreatment of infection that may be developed during hospital stay. The relevant antibiotic may, however, some side effects andadverse event. The present study aimed to investigate whether the side effects and adverse events of the prophylactic antibioticswere considered as a complication or medical negligence.Material and Methods: Descriptive statistics were used for the evaluation of the data.Results: No studies were found in the literature. Ceftriaxone, ampicillin-sulbactam, and cefazolin sodium were preferred forantibiotherapy. Meropenem or vancomycin was solely administered to patients when observed active pathogens in cultureantibiogram.Clinicians should be cautioned the potential side effects and adverse events of some drugs frequently used in clinics.Conclusion: Otherwise, they may legally be held liable for medical negligence.

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1. Han Z, Lat I, Pollard SR. Safety and efficacy of corticosteroid use in neurologic trauma. J Pharm Pract 2014;27:487-95.
2. Picetti E, Caspani ML, Iaccarino C, et al. Intracranial pressure monitoring after primary decompressive craniectomy in traumatic brain injury: a clinical study. Acta Neurochir (Wien) 2017;159:615-22.
3. Galla S, Chakraborty S, Cheng X, et al. Disparate effects of antibiotics on hypertension. Physiol Genomics 2018;50: 837-45.
4. Algan B. Rethinking “Third Generation” Human Rights, Ankara Law Review 2004;1:121-55.
5. Frans Viljoen, International Human Rights Law: A Short History. UN Chronicle, 2009, Retrieved from http:// unchronicle.un.org/article/internationalhuman-rights-lawshort- history/
6. Pocar F. Some Thoughts On The Unıversal Declaration Of Human Rights And The “Generatıons” Of Human Rights. Intercultural Human Right Review 2015;10:43-52.
7. The Constitution of World Health Organisation, https:// www.who.int/governance/eb/who_constitution_en.pdf. accessed date 15.05.2019
8. Nations Unis, Organization Mondial de la Santé, Le Droit à la Santé, Fiche d’Information 31;1-65. https://www.ohchr. org/Documents/Publications/Factsheet31_fr.pdf. accessed date 15.05.2019.
9. The Universal Declaration of Human Rights, https://www. un.org/en/universal-declaration-human-rights/ accessed date 15.05.2019,
10. The European Social Charter (Revised), 1996, https:// rm.coe.int/168007cf93, accessed date 30.05.2019.
11. The Convention on Human Rights and Biomedicine,1997, https://www.coe.int/en/web/conventions/full-list/-/ conventions/rms/090000168007cf98, accessed date 30.05.2019.
12. Temiz O. Turk Hukukunda Bir Temel Hak Olarak Saglik Hakki. Ankara Univesitesi SBF Dergisi 2014;69:165-88.
13. Karaarslan N, Yilmaz I, Ozbek H, et al. Systematic Evaluation of Promising Clinical Trials-Gene Silencing for the Treatment of Glioblastoma. Turk Neurosurg 2019;29:328-34.
14. Karaarslan N, Yilmaz I, Akgun FS, et al. Systematic Evaluation of Desmopressin Applied to the Patients with Aneurysmal Subarachnoid Haemorrhage in the light of the Literature. Turk Neurosurg 2018 Apr 9.
15. Selbst SM. Pediatric emergency medicine: legal briefs. Pediatr Emerg Care 2010;26:778-81.
16. Schein OD. Contact lens abrasions and the nonophthalmologist. Am J Emerg Med 1993;11:606-8.
17. Saxe DB. Psychiatric treatment and malpractice. Med Leg J 1969;37:187-96.
18. Johansson SG, Bieber T, Dahl R, et al. Revised nomenclature for allergy for global use: Report of the nomenclature review committee of the World Allergy Organization, October 2003. J Allergy Clin Immunol 2004;113:832-6.
19. Paul Hunt, The Right to Health: From the Margins to the Mainstream, The Lancet, Volume 360, 2002, p.1878.
20. Decision of the Turkish Constitutional Court, 2013/2084 (Ahmet Acartürk) paragraph 49, https:// kararlarbilgibankasi.anayasa.gov.tr/BB/2013/2084? BasvuruAdi=ahmet+acart%C3%BCrk, accessed date 17.06.2019.
21. Decision of the Turkish Constitutional Court, 2014/18266 (Tevfik Gayretli), paragraph: 31, https://kararlarbilgibankasi. anayasa.gov.tr/BB/2014/18266?BasvuruAdi=TEVF%C4% B0K+GAYRETL%C4%B0, accessed date 17.06.2019
22. Decision of the European Court of Human Rights, Vo/ France, 53924/00, paragraph: 89, https://hudoc.echr.coe. int/eng#{%22itemid%22:[%22001-61887%22]}, accessed date : 17.06.2019.
23. Decision of the European Court of Human Rights, Lopes de Sousa Fernanded/Portugal,56080/13, paragraph: 165-166, https://hudoc.echr.coe.int/ eng#{%22itemid%22:[%22001-179556%22]}, accessed date 17.06.2019.
24. Mertes PM, Ebo DG, Garcez T, et al.Comparative epidemiology of suspected perioperative hypersensitivity reactions. Br J Anaesth 2019 Mar 4. pii: S0007-0912:30069-8.