A demographic study of colorectal cancer in a state hospital with 149 consecutive patient

A demographic study of colorectal cancer in a state hospital with 149 consecutive patient

Aim: Colorectal carcinoma (CRC) is the third most common cancer in both men and women in the United States and the secondleading cause of cancer-related mortalities overall. This study aimed to determine and present the risk factors contributing tomortality and morbidity in 149 retrospectively-evaluated patients with CRC who had been urgently and electively operated on in asecondary healthcare facility.Material/Methods: Overall, 149 patients with CRC who underwent emergency and elective surgery in Çanakkale State Hospitalbetween January 2014 and March 2018, were retrospectively evaluated.Results: Of the 149 patients, 79 (53.1%) were male and 70 (46.9%) were female. The mean age was 68.49 ± 10.79 years. Rectum was themost common anatomic tumor location (31.5%) and the least common location was the transvers colon (2.1%). Histopathologically,the most common tumor type was adenocarcinoma (88.6%), followed by mucinous adenocarcinoma (8.6%). 67.7% of the patientsunderwent elective surgery and 32.2% underwent emergency surgery. The most common complication was wound site infection(14.7%). Although the mortality rate was 4.7% in all cases (emergency/elective), it was 12.5% in emergency cases. The mortality ratefor patients over 80 years of age were 27.3%.Discussion: CRCs have a high mortality rate if they are widespread, especially in patients of 80 and if they require emergencyintervention. When morbidity, mortality, and costs, such as postoperative patient care and stoma, are considered; it can be concludedthat screening programs for low mortality and early diagnosis of CRC in patients before the age of 80 should be developed further,risk factors should be identified, and protective measures should be implemented.Conclusion: A demographic study of colorectal cancer with 149 patients

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  • 1- Nwafor CC, Nwafor NN. The pattern and distribution of cancers in Akwa Ibom State, Nigeria. Niger J Clin Pract 2018;21:603-8.
  • 2- Gendler S, Shmilovich H, Aranovich D, et al. Urgent laparotomy in patients with metastatic colorectal cancer presenting as an acute abdomen: A Retrospective Analysis. Isr Med Assoc J 2018;20:619-622.
  • 3- Ozkan OF, Goret NE, Goret CC. The histopathological changes after neoadjuvant theraphy for rectal carcinoma. LOJ Med Sci 2018;1:LOJMS.MS.ID.000102.
  • 4- Siegel R, Ma J, Zou Z, et al. Cancer statistics, 2014. Cancer J Clin, 2014;64:9-29.
  • 5- Canbey Goret C, Goret NE. Histopathological Analysis of 173 Consecutive Patients with Colorectal Carcinoma: A Pathologist’s View.Med Sci Monit 2018;24:6809-15.
  • 6- EuroSurg Collaborative. Body mass index and complications following major gastrointestinal surgery: a prospective, international cohort study and meta-analysis. Colorectal Dis 2018;20:O215-O225.
  • 7- Amri R, Bordeianou LG, Sylla P, et al. Colon cancer surgery following emergency presentation: effects on admission and stage-adjusted outcomes. Am J Surg 2015;209:246- 53.
  • 8- Askari A, Malietzis G, Nachiappan S, et al. Defining characteristics of patients with colorectal cancer requiring emergency surgery. Int J Colorectal Dis 2015;30: 329-36.
  • 9- Danzi M, Grimaldi L, De Capua M, et al. Obstructing left sided colorectal cancer. A retrospective single center study. Ann Ital Chir 20187;7.
  • 10- Musa AA, Agboola AO, Banjo A A, et al. Rectal carcinoma in a nine-year- old Nigerian male child: Case report. East Afr Med J 2007;82:93-6.
  • 11- Ibrahim KO, Anjorin AS, Afolayan AE, Badmos KB. Morphology of colorectal carcinoma among Nigerians: a 30-year review. Niger J Clin Pract 2011;14:432-5.
  • 12- Abdulkareem FB, Abudu EK, Awolola NA, et al. Colorectal carcinoma in Lagos and Sagamu, Southwest Nigeria: A histopathological review. World J Gastroenterol 2008;14:6531-5.
  • 13- Elesha SO, Owonikoko TK. Colorectal neoplasms: A retrospective study. East Afr Med J 1998;75:718-23.
  • 14- Aykan NF, Yalçın S, Turhal NS, et al. Epidemiology of colorectal cancer in Turkey: A cross-sectional disease registry study (A Turkish Oncology Group trial). Turk J Gastroenterol 2015;26:145-53.
  • 15- Sule AZ, Mandong BM, Iya D. Malignant colorectal tumors: A ten year review in Jos, Nigeria. West Afr J Med 2001;20:251- 5.
  • 16- Hasbahceci M, Idiz O, Cengiz MB, et al. Risk factors for readmission following colorectal cancer surgery. Acta Oncologica Turcica 2017;1:36-42.
  • 17- Seydaoğlu G, Özer B, Arpacı N, et al. Trends in colorectal cancer by subsite, age, and gender over a 15-year period in Adana, Turkey: 1993-2008.Turk J Gastroenterol 2013;24:521-31.
  • 18- Hamilton SR, Bosman FT, Boffetta P, et al. Carcinoma of the colon and rectum. In: Bosman FT, Carneiro F, Hruban RH, Theise ND, eds. WHO classification of tumours of the digestive system. 4th edition. Lyon France: IARC Press; 2010:134–46.
  • 18- Langner C, Harbaum L, Pollheimer MJ, et al. Mucinous differentiation in colorectal cancer indicator of poor prognosis? Histopathology 2012;60:1060-72.
  • 19- Mayir B, Ensari CO, Durhan A, et al. Colonoscopy Findings in Patients Who Have Positive Fecal Occult Blood Test for Colorectal Cancer Screening. Turk J Colorectal Dis 2018;28:27-30.
  • 20- Kalcan S, Sisik A, Basak F, et al. Evaluating factors affecting survival in colon and rectum cancer: A prospective cohort study with 161 patients. J Can Res Ther 2018;14:416-20.
  • 21- Biondo S, Martí-Ragué J, Kreisler E, et al. A prospective study of outcomes of emergency and elective surgeries for complicated colonic cancer. Am J Surg 2005;189:377-83.
  • 22- Ait Ouakrim D, Pizot C, Boniol M, et al. Trends in colorectal cancer mortality in Europe: retrospective analysis of the WHO mortality database. BMJ 20156;351:h4970.
  • 23- Gülcü B, Yılmazlar T, Işık Ö, Öztürk E. Colorectal cancer surgery in octogenarians. Turk J Surg 201818;34:271-5.
Annals of Medical Research-Cover
  • Yayın Aralığı: Aylık
  • Yayıncı: İnönü Üniversitesi Tıp Fakültesi
Sayıdaki Diğer Makaleler

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