Mehmet DİRİ, Bülent BAŞ, Ender YARSAN

Türkiye’deki yarış atlarının solunum yollarından izole edilen Streptococcus spp. ve Staphylococcus spp. etkenlerinin antibiyotik direnci

Diğer hayvan türlerinde olduğu gibi yarış atı yetiştiriciliğinde karşılaşılan en önemli zorluklardan birisi enfeksiyöz hastalıklardan kaynaklanan performans ve ekonomik kayıplardır. Antibiyotikler, enfeksiyöz hastalıklara karşı mücadelede kullanılan en önemli ve yaygın ilaçlardır. Son zamanlarda antibiyotik direncinin oluşması ile birlikte insan ve hayvan sağlığı açısından ciddi komplikasyonlar ortaya çıkarmaktadır. Bu nedenle, bakterilerde oluşan antibiyotik direncinin tespiti amacıyla dünyada ve Türkiye’de yapılmış bir çok araştırma bulunmaktadır. Ancak Türkiye’de, yarış atlarında antibiyotik direnci üzerine kapsamlı bir çalışmaya rastlanılmamıştır. Bu çalışma kapsamında 75. Yıl Hipodromu At Hastanesine getirilen safkan atlardan alınan trakeal aspirasyon sıvısı numunelerinden izole edilerek identifiye edilen Streptococcus spp. ve Staphylococcus spp. etkenlerinde antibakteriyel duyarlılık ve direncin araştırılması amaçlandı. Antibakteriyel duyarlılığın tespitinde Disk Difuzyon ve Minimum İnhibitör Konsantrasyon (MIC) testlerinden yararlanıldı. Tespit edilen suşların bazı penisilin, sefalosporin, aminoglikozid, tetrasiklin, rifamisin ve karbapenem grubu antibakteriyel ilaçlara karşı duyarlılık profilleri çıkarıldı. 1 Streptococcus spp. ve 10 Staphylococcus spp.’nin amoksisilin ve ampisilin- sulbaktam’a duyarlı; penisilin ve amikasine orta derecede duyarlı; trimetoprim-sülfametoksazol, kanamisin, gentamisin, enrofloksasin ve rifampine ise dirençli olduğu tespit edildi.

Antimicrobial resistance of Streptococcus spp. and Staphylococcus spp. isolated from respiratory tract of race horses in Türkiye

As with other animal species, one of the most important challenges encountered in race horse breeding is performance and economic losses caused by infectious diseases. Antibiotics are the most important and common drugs used for protection against infectious diseases. Recently with the occurrence of antibiotic resistance, serious complications have emerged in terms of human and animal health. For this reason, to determine antibiotic resistance in bacteria, many research studies have been carried out in the world and Türkiye. However, in Türkiye no comprehensive study has yet been conducted on antibiotic resistance in race horses. Within the scope of this study, it was aimed to investigate antibacterial susceptibility and resistance in Streptococcus spp. and Staphylococcus spp. agents identified through isolation from tracheal aspiration fluid samples taken from thoroughbred horses brought to 75. Yıl Hippodrome Hospital. Disk Diffusion and Minimum Inhibitory Concentration (MIC) tests were used to determine antibacterial susceptibility. Susceptibility profiles of identified strains against some penicillin, cephalosporin, aminoglycoside, tetracycline, rifamycin and carbapenem group antibacterial drugs were determined. Also, it has been determined that 1 Streptococcus spp. and 10 Staphylococcus spp. agents are sensitive to amoxicillin and ampicillin-sulbactam; moderately sensitive to penicillin and amikacin and resistant to trimethoprim-sulfamethoxazole, kanamycin, gentamicin, enrofloxacin and rifampin.

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