Neslihan ALKIŞ, Çağıl VURAL, Özlem Selvi CAN, Çiğdem YILDIRIM GÜÇLÜ, Zekeriyya ALANOĞLU, Süheyla KARADAĞ ERKOÇ

Sitoredüktif Cerrahi ve Hipertermik İntraperitoneal Kemoterapi Uygulanan Hastalarda Anestezi Yönetimi ve Perioperatif Sonuçlar

Amaç: Sitoredüktif cerrahi (SRC) ve hipertermik intraperitoneal kemoterapi (HİPEK) uygulaması uzun ve kompleks bir işlemdir. Perioperatif dönemdeönemli derecede kan ve sıvı kaybı, hemodinamik, hematolojik ve metabolik değişiklikler ve bunlara bağlı olarak yüksek morbidite ve mortalite ileseyretmektedir. Bu çalışmada ameliyathanemizde SRC ve HİPEK yapılan hastalar retrospektif olarak değerlendirildi.Gereç ve Yöntem: SRC ve HİPEK uygulanan 26 hastanın dosyası retrospektif olarak tarandı. Preoperatif, intraoperatif ve postoperatif kayıtlarıincelenerek, yapılan kan/kan ürünü ve sıvı replasmanları, metabolik değişiklikler, postoperatif komplikasyonlar, yoğun bakım ve hastanedeki kalışsüreleri ve mortalite oranları değerlendirildi.Bulgular: Çalışmaya dahil edilen 26 hastanın 7’si erkek, 19’u kadındı. Hastaların primer tanıları sıklık sırasına göre over kanseri (%42,3), kolorektalkanser (%15,3), malign peritoneal mezotelyoma (%15,3), psödomiksoma peritonei (%11,5) ve diğer malign hastalıklardı (%15,3). Preoperatif değerlerile karşılaştırıldığında postoperatif hemoglobin, hematokrit, trombosit ve albümin değerlerinde azalma görüldü (p

Anesthesia Management and Perioperative Outcomes in Patients Undergoing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy

Objectives: Cytoreductive surgery (SRC) and hyperthermic intraperitoneal chemotherapy (HIPEC) implementation is a prolonged and complex procedure. Major blood and fluid loss, hemodynamic, hematological and metabolic changes are associated with high morbidity and mortality in the perioperative period. In this study, patients who underwent SRC and HIPEC in our operating room were retrospectively analyzed. Materials and Methods: The files of 26 patients who underwent SRC and HIPEC were reviewed retrospectively. Preoperative, intraoperative and postoperative records were examined, blood/blood product and fluid replacements, metabolic changes, postoperative complications, length of stay in intensive care and hospital and mortality rates were evaluated. Results: There were 26 patients included in the study, 7 of them were male and 19 were female. The primary diagnoses of the patients were ovarian cancer (42.3%), colorectal cancer (15.3%), malignant peritoneal mesothelioma (15.3%), pseudomyxoma peritonei (11.5%) and other malignant diseases (15.3%). There was a decrease in postoperative hemoglobin, hematocrit, platelet and albumin values compared to preoperative values (p

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