Gül BORA, Necdet ÖZALP, Bilgehan Ça?daL SONBAHAR

Ayın Vakada Eşzamanlı Görülen Mide ve Kolon Kanseri: Olgu Sunumu ve Literatür Derlemesi

Bilindi?i üzere senkron mide ve kolon kanseri nadir görülen bir durumdur. Biz burada senkron iki tümörün formu olan mide ve kolon adenokanseri vakasÖnÖ bildiriyoruz. 74 yaLÖnda kadÖn hasta klini?imize epigastrik a?rÖ ve yanma Likayetiyle baLvurdu. Hastaya gastroskopi yaptÖk ve midede malign kitle gördük. ?ikayeti olmamasÖna ra?men hastaya kolonoskopi yaptÖk ve sa? kolonda malign kitle ve polip saptadÖk. YaLlÖ hastalarda gastrointestinal traktusta baLka bir senkron tümör olabilece?ini unutmamak gerekti?ini öneriyoruz

Synchronous Gastric and Colon Carcinomas: A Case Report and Review of Literature

As is known synchronous gastric and colon cancer is rare. Here we report the synchronous two malignancies in form of gastric adenocarcinoma and colon adenocarcinomas. A 74 year old female patient was admitted to our department with epigastric pain and heartburn. We performed gastroscopy and saw gastric malignant mass. Despite the lack of patient complaints we did colonoscopy and detected malignant synchronous mass and colonic polip in right colon. We suggest, not to forget in older patient there will be another synchronous malignancies at other gastrointestinal tractus.

PDF

___

1. Watson TA. Incidence of multiple cancer. Cancer 1953; 6: 365-371.
2. Warren S, Gates O. Multiple primary malignant tumours. A survey of the literature and a statistical study. Am J Cancer 1932; 16: 1358-1314.
3. Ji J, Hemminki K. Second gastric cancers among patients with primary sporadic and familial cancers in Sweden. Gut 2006; 55: 896-898.
4. Lag Melbert D, Krapcho M, Stinchcomb DG, et al. Surveillance, epidemiology and end results (SEER) Cancer Statistics Review, 1975-2005, National Cancer Institute. Bethesda, MD, http://seer. cancer.gov/csr/1975_2005/ based on November 2007 SEER data submission, posted to the SEER web site, 2008.
5. TC Saglik Bakanligi Kanserle Savas Dairesi Baskanligi. 2005 Turkiye Kanser Istatistikleri. http://www.saglik.gov.tr/KSDB/ dosyagoster.aspx?DIL=1&BELGEANAH= 34879&DOSYAISIM=Kanser Istatistikleri.xls.
6. Ha TK, An JY, Youn HG, et al. Surgical outcome of synchronous second primary cancer in patients with gastric cancer. Yonsei Med J 2007; 48: 981-987.
7. Yano K, Yamashita T, Chishiki M, Osaki T, Sugio K, Yasumoto K. Two cases of synchronous superficial double cancers in the esophagus and stomach. J UOEH 2002. 24: 225-232.
8. Onoue S, Katoh T, Chigira H, et al. Synchronous multiple primary cancers of the stomach and duodenum in aged patients: report of two cases. Sur Today 2000; 30: 735-738.
9. Dinis-RM, Lomba VH, Silva R, Moreira L, Lomba VR. Associated primary tumours in patients with gastric cancer. J Clin Gastroenterol 2002; 34: 533-535.
10. Tamura M, Shinagawa M, Funaki Y. Synchronous triple early cancers occurring in the stomach, colon and gallbladder. Asian J Surg 2003; 26:46-48;
11. Sato K , Maekawa T, Yabuki K, et al. Case of triple synchronous cancers occurring in the gallbladder, common bile duct, and pancreas. J Gastroenterol 2003; 38:97-100.
12. Lee JH, Bae JS, Ryu KW, et al. Gastric cancer patients at high-risk of having synchronous cancer. World J Gastroenterol 2006;12:2588-2592.
13. áawniczak M, Gawin A, JaroszewiczHeigelmann H, et al. Synchronous and metachronous neoplasms in gastric cancer patients: a 23-year study. World J Gastroenterol. 2014 21;20:7480-7487.
14. Ikeda Y, Saku M, Kawanaka H, et al Features of second primary cancer in patients with gastric cancer. Oncology 2003;65:113-117.
15. Yoshino K, Asanuma F, Hanatani Y, et al. Multiple primary cancers in the stomach and another organ: frequency and the effects on prognosis. Jpn J Clin Oncol 1985;15 Suppl 1:183-190.
16. Cheng HY, Chu CH, Chang WH, et al. Clinical analysis of multiple primary malignancies in the digestive system: a hospital-based study. World J Gastroenterol 2005;11:4215-4219.
17. Furukawa H, Hiratsuka M, Iwanaga T, et al. Treatments for second malignancies after gastrectomy for stomach cancer. Hepatogastroenterology 1996;43:194-198.
18. Ikeguchi M, Ohfuji S, Oka A, et al. Synchronous and metachronous primary malignancies in organs other than the stomach in patients with early gastric cancer. Hepatogastroenterology 1995;42: 672-676.
19. Nio Y, Hirahara N, Minari Y, et al. Second malignancies after a gastrectomy for gastric cancers: the effects of adjuvant therapies. Anticancer Res 1999;19:3591- 3599.
20. Gylling A, Abdel-Rahman WM, Juhola M et al. Is gastric cancer part of the tumor spectrum of hereditary non-polyposis colorectal cancer? A molecular genetic study. Gut 2007;56:926-933
21. Keller G, Grimm V, Vogelsang et al. Analysis for microsatellite instability and mutations of the DNA mismatch repair gene hMLH1 in familial gastric cancer. Int J Cancer 1996;68:571-576.
22. Kim JC, Kim HC, Roh SA, et al mutations in families with familial clustering of gastric cancer and hereditary non-polyposis colorectal cancer. Cancer Detect Prev 2001;25:503-510.
23. Muela Molinero A, Jorquera Plaza F, Ribas Ariño T, et al. Multiple malignant primary neoplasms in patients with gatric neoplasms in the health district of León. Rev Esp Enferm Dig 2006; 98: 907-916
24. Eom BW, Lee HJ, Yoo MW, et al.. Synchronous and metachronous cancers in patients with gastric cancer. J Surg Oncol 2008; 98: 106-110
25. Kim JP, Hur YS, Yang HK. Lymph node metastasis as a significant prognostic factor in early gastric cancer: analysis of 1,136 early gastric cancers. Ann Surg Oncol 1995;2:308-313.
26. Skoropad VIu, Bedrov BA, Rukhadze GO. Multiple neoplasms in gastric cancer patients: patterns of development, results of treatment. Vopr Onkol. 2012;58:754- 761.
27. Kato T, Suzuki K, Muto Y, et al.. Multiple primary malignancies involving primary sporadic colorectal cancer in Japan: incidence of gastric cancer with colorectal cancer patients may be higher than previously recognized. World J Surg Oncol. 2015 7;13:23.
28. Buyukasik O, Hasdemir AO, Gulnerman Y, et al. Second primary cancers in patients with gastric cancer. Radiol Oncol. 2010;44:239-243.