Ertan TUZLACI, Melek ULUSOYLU, Gürbüz Burçak AKARSU, Elçin GÜRKAN, Soyoğul Ümran GÜRER

The cytotocixity and the antibacterial activities of Rubus sanctus schreber

Rubus sanctus Schreber bitkisinin toprak üstü kısımlarından PE, CHCl3, EtOAc ekstreleri elde edilmiştir. EtOAc ekstresinden triterpenoid yapısında bir madde izole edilmiştir. Tüm ekstreler ve saf madde Brine Shrimp (Artemia salina) yöntemiyle kontrol edilmiş ve daha sonra mikrobiyolojik olarak incelenmiştir.

Rubus sanctus bitkisinin sitotoksik ve antibakteriyel aktiviteleri

PE, CHCl3, EtOAc extracts were obtained from the aerial parts of Rubus sanctus Schreber. A triterpenoid compound was isolated from the EtOAc extract. All extracts and the pure compound were controlled with the Brine Shrimp (Artemia salina) method. After that microbiological methods were applied to the extracts and the pure compound.

PDF

___

1. Davis, P.H., Flora of Turkey and The East Aegean Islands, Edinburg University Press.,Volume 4, Edinburg, 1982.
2. Niero, R., Flho, C, Souzo, M.M., Montanari, J.L., Yunes, R.A.Antinoniceptive Activity of Niga-ichigoside Fj from Rubus imperialis", JJSfat.Prod., 62, 1145-1146 (1999).
3. Wang, B.,Zhu,W., Jia,Z.,hao,X. "Rubupungenosides A and B , Two novel triterpenoid Saponin Dimers from the Aerial parts oîR.pungens", J.Nat.Prod., 63, 851-854 (2000).
4. Baytop,T., Theraphy with Medicinal Plants in Turkey, Nobel Press, 171,1999.
5. Li.B'Wang,B.,Jiay,Z. "Pentacyclic Triterpenoids from R. xanthocarpus" Phytochemistry, 49(8), 2477-2481 (1998).
6. Richards,R.M.E., Durham,D.G., Liu.X., "Antibacterial Activity of Compounds from Rubuspinfaensis", Planta Med., 60,471-473 (1994).
7. Dey,P.M., Harborne, J.B. "Methods in Plant Biochemistry" , Volume 6, Academic Press., New York, 1991.
8. Shadomy,S.,Pfaller M.A. "Laboratory studies with antifungal agents: Susceptibilities test and quantitation in body fluids, Manual Clinical Microbiology" American Society for Microbiology, Washington, 1173-1183,1191.
9. National Comittee for Clinical Laboratory Standarts. Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria taht Grow Aerobically. Approved Standart M7-A3.National Comittee for Clinical Laboratory Standarts, Villanova.,Pa.,1993.