PROLİPOZOM TEKNOLOJİSİNDEKİ GÜNCEL GELİŞMELER VE UYGULAMALAR

Amaç: Lipozomlar, ilaç taşıyıcı sistemler arasında en umut verici ve uygulanabilir olanıdır. Ancak, lipozomların fiziksel ve kimyasal stabilite problemleri kullanımlarını sınırlamaktadır. Bu problemlerin üstesinden gelmek için 1986 yılında prolipozomal sistemler geliştirilmiştir. Bu derleme kapsamında prolipozomal ilaç taşıyıcı sistemler ve uygulamaları ile ilgili yapılmış olan bilimsel araştırmalar akademik veri tabanları taranarak sunulmuştur.

RECENT DEVELOPMENTS ON PROLIPOSOME TECHNOLOGY AND APPLICATIONS

Objective: Liposomes are the most promising and feasible carriers among other drug delivery systems. However, physical and chemical stability problems of liposomes limit their use. In order to overcome these problems, proliposomal systems were developed in 1986. Within the scope of this review, scientific researches about proliposomal drug delivery systems and their applications were presented by searching academic databases.

Keywords:

drug delivery systems, liposome proliposomes, stability,

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