Spil (Manisa)’ dan toplanan Ranunculus pedatus Waldst.&Kit. subsp. pedatus, Yamanlar (İzmir)’ den toplanan R. constantinapolitanus DC. ve Bozdağ (İzmir)’ den toplanan R. isthmicus Boiss. subsp. tenuifolius bitki örneklerinden hazırlanan n-hekzan, etil asetat, metanol, etanol ve su ekstreleri üzerinde Brine shrimp (Artemia salina) yöntemi ile sitotoksik aktivite tayini yapılmış ve LC50 değerleri hesaplanmıştır. R.pedatus Waldst.&Kit. subsp. pedatus’ un n-hekzan, etil asetat, metanol ve su ekstreleri, R. constantinapolitanus DC.’ nin n-hekzan, etil asetat ve su ekstreleri ve R. isthmicus Boiss. subsp. tenuifolius’ un n-hekzan, etanol ve su ekstreleri sitotoksik aktivite göstermiştir

The cytotoxic activity of Ranunculus pedatus Waldst.&Kit. subsp. pedatus growing wildly in Spil (Manisa), R. constantinapolitanus DC. growing wildly in Yamanlar (İzmir), R. isthmicus Boiss. subsp. tenuifolius growing wildly in Bozdağ (İzmir) respectively were determined. LC50 value of n-hexane, ethyl acetate, ethanol, methanol and water extracts of the plant materials were determined using brine shrimp (Artemia salina) lethality bioassay. The n-hexane, ethyl acetate, methanol and water extracts of R.pedatus Waldst.&Kit. subsp. pedatus, the n-hexane, ethyl acetate and water extracts of R. constantinapolitanus DC. and the n-hexane, ethanol and water extracts of R. isthmicus Boiss. subsp. tenuifolius showed cytotoxic activity against the Brine shrimp