Migren ve ABO Kan Grubu İlişkisi

Amaç: ABO kan grubu ile ilgili hastalıklar bulaşıcı hastalıklar (kolera, helicobacter pylori, echerichia coli), kardiyovasküler hastalık, maligniteler ve alerjik durumlardır. Çalışmamızda ABO kan grubu ile migren arasındaki ilişkiyi araştırmayı amaçladık. Materyal ve Metot: Nöroloji polikliniğinde Ocak 2008 ve Aralık 2018 tarihleri arasında migren tanısı almış ve kan grubu olan 985 erişkin hasta dosyası geriye dönük olarak incelendi. Hastane bilgi sisteminden hastaların yaş, cinsiyet ve kan grupları kaydedildi. Bulgular: Hastalarda kan gruplarının dağılımı: A Rh+: 383(%38,89), A Rh-: 53(%5,38), B Rh+: 148(% 15,03), B Rh-: 16(% 1,62), AB Rh+: 93(%9,44), AB Rh-: 8(% 0,81), 0 Rh+: 257(% 26,09), 0 Rh-: 27(% 2,74) bulundu. Sonuç: Çalışmamızda A Rh+ kan grubunun migren hastalarında en sık görülen kan grubu olduğunu bulduk.

Relationship Between ABO Blood Group and Migraine

Objectives: Disorders related with ABO blood group are infectious disease (cholera, helicobacterpylori, echerichia coli), cardiovascular disease, malignancies and allergic status. We aimed to elucidatethe association between ABO blood group and migraine.Materials and Methods: We investigated retrospectively the files of 985 adult patients who werediagnosed with migraine and had blood type between January 2008 and December 2018 in neurologyoutpatient clinics included in the study. The age, gender and blood group of the patients scanned andrecorded retrospectively from the hospital data system.Results: Distribution of blood groups in patients as follows: A Rh+: 383(38.89 %), A Rh-: 53(5.38 %), BRh+: 148 (15.03 %), B Rh-: 16(1.62 %), AB Rh+: 93(9.44 %), AB Rh-: 8(0.81 %), 0 Rh+: 257(26.09 %), 0 Rh-:27(2.74 %).Conclusion: We found that in our study A Rh+ blood group was most prevalence blood group inmigraine patients.

PDF

___

eferences 1. Anstee DJ. The relationship between blood groups and disease. Blood. 2010;115:4635-43.
2. Liumbruno GM, Franchini M. Beyond immunohaematology: the role of the ABO blood group in human diseases. Blood Transfus. 2013;11(4):491-9.
3. A Hong Kong tuberculosis treatment services/British medical research council investigation. Investigations of allergic status and blood counts in Chinese patients receiving daily or intermittent rifampicin in Hong Kong. Clin Allergy. 1975;5(2):189-99.
4. Pourafkari L, Ghaffari S, Ahmadi M, Tajlil A, Nader ND. Association of ABO blood types with the risk of in-stent restenosis. Perfusion. 2015;30(6):507-13.
5. Dagdeviren M, Ates I, Demir BF, Ergun E, Yildiz C, Altay M. Investigation of blood groups in benign thyroid diseases in Turkey. Endocr J. 2019 Jul 12. doi: 10.1507/endocrj.EJ18-0582. [Epub ahead of print]
6. İslamoğlu ZGK, Unal M. Is there an association of ABO blood groups and Rhesus factor with alopecia areata? J Cosmet Dermatol. 2018;17:1271–4
7. Pare G, Chasman DI, Kellogg M, Zee RY, Rifai N, Badola S, et al. Novel association of ABO histoblood group antigen with soluble ICAM-1: results of a genome-wide association study of 6,578 women. PLoS genetics. 2008;4(7):e1000118.
8. Melzer D, Perry JR, Hernandez D, Corsi AM, Stevens K, Rafferty I, et al. A genome-wide association study identifies protein quantitative trait loci (pQTLs). PLoS genetics. 2008;4(5):e1000072.
9. Park EJ, Lee JH, Yu GY, He G, Ali SR, Holzer RG, et al. Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression. Cell. 2010;140(2):197- 208.
10. Balazs C. The role of hereditary and environmental factors in autoimmune thyroid diseases. Orvosi hetilap. 2012;153(26):1013-22.
11. Valikhani M, Kavand S, Toosi S, Kavand G, Ghiasi M. ABO blood groups, Rhesus factor and pemphigus. Indian J Dermatol. 2007;52:176–8.
12. Eiermann T.H., Vejbaesya S., Prestel H, Roepke A, Muller-Myhsok B., Schmitt-Egenolf M. Association and linkage of human leukocyte antigens with psoriasis-revisited. Infus Ther Transfus Med. 2002;29:326-30.
13. Olesen J. International Classification of Headache Disorders. Lancet Neurol. 2018;17(5):396-7.
14. Charles A. The pathophysiology of migraine: implications for clinical management. Lancet Neurol. 2018;17(2):174-82.
15. Yıldız ŞM. Distribution of ABO and Rh blood group systems in Cukurova region. Cukurova Med J 2016;41(4):658-63.
16. Beardmore JA, Karimi-Booshehri F. ABO genes are differentially distributed in socio-economic groups in England. Nature. 1983;303(5917):522-4.
17. Galip Akın ND. Türkiye'de kan grubu araştırmaları. Ankara Üniversitesi Dil ve Tarih-Coğrafya Fakültesi Dergisi. 2005;45(2):1-15.
18. Demet Özdemir HE, Aysenur Ucar. Blood Groups Distributions of Donors/Patients in a Tertiary Hospital. Sakarya Med J. 2018;8(4):753-8.
19. Mehne P, Grunwald P, Gerner-Beuerle E. A serogenetic approach to the study of Alzheimer's disease (author's transl). Aktuelle Gerontol. 1976;6(6):259-66.
20. Renvoize EB. ABO and Rhesus blood groups in Alzheimer's disease. Age Ageing. 1985;14(1):43-5.
21. Franchini M, Liumbruno GM. ABO blood group and neurodegenerative disorders: more than a casual association. Blood Transfus. 2016;14(2):158-9.
22. Nishi K., Gupta N.K., Sharma S.C. Study on the Incidence of Hypertension and Migraine in ABO Blood Groups. ISCA Journal of Biological Sciences. 2012;1(2):12-6.