Vitamin D eksikliği olan bireylerde paratiroid bezlerinin ultrasonografik değerlendirilmesi ve paratiroid bezi boyutlarının anksiyete-depresyon ile ilişkisinin belirlenmesi

Amaç: Bu çalışmada amacımız vitamin D eksikliği olanlarda paratiroid bezinin ultrasonografi (US) ile değerlendirilmesi ve paratiroid bezi boyutlarının anksiyete-depresyon ile ilişkisinin belirlenmesidir. Materyal ve method: Bu çalışmaya vitamin D eksikliği olan ve vitamin D düzeyleri normal saptanan 30-65 yaş arası 39 birey dahil edildi (24 vitamin D eksikliği grubu, 15 kontrol grubu). Vitamin D düzeyi

___

  • Fraser WD. Hyperparathyroidism. Lancet. 2009;374:145–158.
  • Dawson-Hughes B, Harris SS, Dallal GE. Am J Clin Nutr. Vol. 65. Press: OUP Academic. Oxford University; 1997. Plasma calcidiol, season, and serum parathyroid hormone concentrations in healthy elderly men and women; pp. 67–71.
  • Hussain A et al. Parathyroid Gland Response to Vitamin D Deficiency in Type 2 Diabetes Mellitus: An Observational Study. Cureus 2018; 10(11): e3656.
  • Prevention and management of osteoporosis. https://www.ncbi.nlm.nih.gov/pubmed/15293701. World Health Organ Tech Rep Ser. 2003;921:1–164.
  • Dawson-Hughes B, Heaney RP, Holick MF, Lips P, Meunier PJ, Vieth R. Estimates of optimal vitamin D status. Osteoporos Int. 2005;16:713–716.
  • Wallace AM, Gibson S, de la Hunty A, Lamberg-Allardt C, Ashwell M. Measurement of 25-hydroxyvitamin D in the clinical laboratory: current procedures, performance characteristics and limitations. Steroids. 2010;75:477–488.
  • Mesci E, Mesci N, and İçağasıoğlu A. "D vitamini eksikliğinin yorgunluk, gündüz uykululuk hali ve fiziksel aktivite düzeyi ile ilişkisi." Turkish Journal of Physical Medicine & Rehabilitation/Turkiye Fiziksel Tip ve Rehabilitasyon Dergisi.206;62(3):222-28.
  • Alencar et al. Depression and quality of life in older adults on hemodyalisis. Braz J Psychiatry 2019. Doi: 10.1590/1560-4446-2018-0345.
  • Yavuz YC et al. Assosiation of depressive symptoms with 25-OH vitamin D in hemodialysis patients and effect of gender. Clinical and Experimental Nephrology 2020;24(1):63-72.
  • Prüfer K, Veenstra TD, Jirikowski GF, Kumar R. Distribution of 1,25-dihydroxyvitamin D3 receptor immunoreactivity in the rat brain and spinal cord. J Chem Neuroanat. 1999;16:135–45.
  • Mora JR, Iwata M, von Andrian UH. Vitamin effects on the immune system: Vitamins A and D take centre stage. Nat Rev Immunol. 2008;8:685–98.
  • van Etten E, Stoffels K, Gysemans C, Mathieu C, Overbergh L. Regulation of vitamin D homeostasis: Implications for the immune system. Nutr Rev. 2008;66(10 Suppl 2):S125–134.
  • Buell JS, Dawson-Hughes B. Vitamin D and neurocognitive dysfunction: Preventing “D”ecline? Mol Aspects Med. 2008;29:415–22.
  • Song C, Wang H. Cytokines mediated inflammation and decreased neurogenesis in animal models of depression. Prog Neuropsychopharmacol Biol Psychiatry. 2011;35:760–8.
  • Menon V, Kar S K, Suthar N, Nebhinani N. Vitamin D and depression: A critical appraisal of the evidence and future directions. Indian Journal of Psychological Medicine 2020; 42(1): 11.
  • Han B, Zhu FX, Yu HF, Liu S, Zhou JL. Low serum levels of vitamin D are associated with anxiety in children and adolescents with dialysis. Scientific reports 2018;8(1): 1-6.
  • Casseb GA, Ambrósi G, Rodrigues ALS, Kaster MP. Levels of 25-hydroxyvitamin D 3, biochemical parameters and symptoms of depression and anxiety in healthy individuals. Metabolic brain disease 2019; 34(2): 527-535.
  • Rumack CM, Wilson SR, Charboneau JW, Levine D. Diagnostic Ultrasound. 4th edition. Philadelphia: Elsevier Mosby; 2011.