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• Aksoy, R., Gürbilek, M. Çetinkaya, Ç.D., & Topcu, C. (2016). Glukoz, fruktoz, nişasta bazlı şekerler ile beslenmiş ratlarda Na⁺/K⁺ ATPaz (E.C.3.1.6.37) aktivitesi, glut ve adipositokinlerin araştırılması. Van Tıp Dergisi, 23(2), 167-175.
• Alzamendi, A., Giovambattista, A., Raschia, A., Madrid, V., Gaillard, R.C., Rebolledo, O., Gagliardino, J.J., & Spinedi, E. (2009). Fructose-rich diet-induced abdominal adipose tissue endocrine dysfunction in normal male rats. Endocrine, 35(2), 227-232.
• Angelopoulos, T.J., Lowndes, J., Zukley, L., Melanson, K.J., Nguyen, V., & Huffman, A. (2009). The effect of high-fructose corn syrup consumption on triglycerides and uric acid. The Journal of Nutrition, 139(6), 1242- 1245.
• Arita, Y., Kihara, S., Ouchi, N., Takahashi, M., & Maeda, K. (1999). Paradoxical decrease of an adipose specific protein, adiponectin, in obesity. Biochemical and Biophysical Research Communications, 257, 79-83.
• Atanasovska, E., Jakovski, K., Kostova, E., Petlichkovski, A., Dimitrovski, C., Bitovska, I., Kikerkov, I., Petrovski, O., & Labachevski, N. (2009). Effects of rosiglitazone on metabolic parameters and adiponectin levels in fructose-fed rats. Macedonian Journal of Medical Sciences, 2(1), 22-29.
• Berg, A.H., Combs, T.P., & Scherer, P.E. (2002). ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism. Trends in Endocrinology and Metabolism, 13, 84-89.
• Bocarsly, M.E., Powell, E.S., Avena, N.M., & Hoebel, B.G. (2010). High-fructose corn syrup causes charecteristics of obesity in rats: Increased body weight, body fat and triglyceride levels. Pharmacology, Biochemistry and Behaviour, 97, 101-106.
• Bonnard, C., Durand, A., Vidal, H., & Rieusset, J. (2008). Changes in adiponectin, its receptors and AMPK activity in tissues of diet-induced diabetic mice. Diabetes and Metabolism, 34, 52-61.
• Brochu-Gaudreau, K., Rehfeldt, C., Blouin, R., Bordignon, V., Murphy, B.D. & Palin, M.F. (2010). Adiponectin action from head to toe. Endocrine, 37, 11-32.
• Bruun, J.M., Lihn, A.S., Verdich, C., Pedersen, S.B., Toubro, S., Astrup, A., & Richelsen, B. (2003). Regulation of adiponectin by adipose tissue-derived cytokines: in vivo and in vitro investigations in humans. American Journal of Physiology Endocrinology and Metabolism, 285, E527-E533.
• Cardinali, D.P., Bernasconi, P.A., Reynoso, R., Toso, C.F., & Scacchi, P. (2013). Melatonin may curtail the metabolic syndrome: Studies on initial and fully established fructose-induced metabolic syndrome in rats. International Journal of Molecular Sciences, 14(2), 2502-2514.
• Chinetti, G., Zawadski, C., Fruchart, J., & Staels, B. (2004). Expression of adiponectin receptors in human macrophages and regulation by agonists of the nuclear receptors PPAR alpha, PPAR gamma and LXR. Biochemical and Biophysical Research Communications, 314, 151-158.
• Choi, Y., Abdelmegeed, M.A., & Song, B.J. (2017). Diet high in fructose promotes liver steatosis and hepatocyte apoptosis in C57BL/6J female mice: Role of disturbed lipid homeostasis and increased oxidative stress. Food and Chemical Toxicology, 103, 111-121.
• Civitarese, A.E., Jenkinson, C.P., Richardson, D., Bajaj, M., Cusi, K., Kashyap, S., Berria, R., Belfort, R., DeFronzo, R.A., Mandarino, L.J., & Ravussin, E. (2004). Adiponectin receptors gene expression and insulin sensitivity in non-diabetic Mexican American with or without a family history of type 2 diabetes. Diabetologia, 47, 816-820.
• Dai, S., & McNeill, J.H. (1995). Fructose-induced hypertension in rats is concentration and duration dependent. Journal of Pharmacological and Toxicological Methods, 33(2), 101-107.
• De Moura, R.F., Ribeiro, C., Oliveira, J.A., Stevanato, E., & Mello, M.A.R. (2008). Metabolic syndrome signs in Wistar rats submitted to different high-fructose ingestion protocols. British Journal of Nutrition, 101(8), 1178-1184.
• Debard, C., Laville, M., Berbe, V., Loizon, E., Guillet, C., Morio-Liondore, B., Boirie Y., & Vidal, H. (2004). Expression of key genes of fatty acid oxidation, including adiponectin receptors, in skeletal muscle of type 2 diabetic patients. Diabetologia, 47, 917-925.
• Forshee, R.A., Storey, M.L., Allison, D.B., Glinsmann, W.H., Hein, G.L., Lineback, D.R., Miller, S.A., Nicklas, T.A., Weaver, G.A., & White, J.S. (2007). Critical examination of the evidence relating high fructose corn syrup and weight gain. Critical reviews in food science and nutrition, 47(6), 561-582.
• Haimes, J., Kelley M: Demonstration of a ΔΔCq calculation method to compute relative gene expression from qPCR data. 2010. GE Heathcare, Tech Note, 1-4. http://dharmacon.gelifesciences.com/uploadedfiles/resources/ delta-cq-solaris-technote.pdf; Accessed: 24.05.2017.
• Hanson, R.L., Imperatore, G., Bennett, P.H., & Knowler, W.C. (2002). Components of the "metabolic syndrome" and incidence of type 2 diabetes. Diabetes, 51(10), 3120-3127. https://doi: 10.2337/diabetes.51.10.3120
• Inukai, K., Nakashima, Y., Watanabe, M., Takata, N., Sawa, T., Kurihara, S., Awata, T., & Katayama, S. (2005). Regulation of adiponectin receptor gene expression in diabetic mice. American Journal of Physiology-Endocrinology and Metabolism, 288, E876-882. https://doi.org/10.1152/ajpendo.00118.2004
• Kadowaki, T., Yamauchi, T., Kubota, N., Hara, K., Ueki, K., & Tobe, K. (2006). Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome. The Journal of Clinical Investigation, 116, 1784-1792. https://doi.org/10.1172/JCI29126
• Kharroubi, I., Rasschaert, J., Eizirik, D., & Cnop, M. (2004). Expression of adiponectin receptors in pancreatic beta cell. Biochemical and Biophysical Research Communications, 312, 1118-1122. https://doi.org/10.1016/j.bbrc.2003.11.042
• Koca, S.S., Özkan, Y., Akbulut, H., Günay, İ., & Dönder, E. (2006). Obezitede azalmış serum adiponektin düzeyi ve orlistat tedavisinin etkisi. Turkiye Klinikleri Journal of Medical Sciences, 26, 126-131.
• Kubota, N., Terauchi, Y., Yamauchi, T., Kubota, T., Moroi, M., Matsu, J., Eto, K., Yamashita, T., Kamon, J., Satoh, H., Yano, W., Froguel, P., Nagai, R., Kimura, S., Kadowaki, T., & Noda, T. (2002). Disruption of adiponectin causes insulin resistance and neointimal formation. The Journal of Biological Chemistry, 277, 25863-25866. https://doi: 10.1074/jbc.C200251200
• Lindsay, R.S., Funahashi, T., Hanson, R.L., Matsuzawa, Y., Tanaka, S., Tataranni, P.A., Knowler, W.C., & Krakoff, J. (2002). Apinonectin and development of type 2 diabtes in the Pima Indian population. Lancet, 360, 57-58. https://doi: 10.1016/S0140-6736(02)09335-2
• Ma, K., Cabrero, A., Saha, P.K., Kojima, H., Li, L., Chang, B.H.J., Paul, A., & Chan, L. (2002). Increased beta-oxidation but no insulin resistance or glucose intolerance in mice lacking adiponectin. The Journal of Biological Chemistry, 277, 34658-34661. https://doi: 10.1074/jbc.C200362200
• Ma, H., You, G.P., Cui, F., Chen, L.F, Yang, X.J., Chen, L.G., Lu, H.D., & Zhang, W.Q. (2015). Effects of a low-fat diet on the hepatic expression of adiponectin and its receptors in rats with NAFLD. Annals of Hepatology, 14(1), 108-117. https://doi: 10.1016/s1665-2681(19)30807-5
• Macda, N., Takahashi, M., Funahashi, T., Kihara, S., Nishizawa, H., Kishio, K., Hishida, K., Nagaretani, H., Matsuda, M., Komuro, R., Ouchi, N., Kuriyama, H., Hotta, K., Nakamura, T., Shimomura, I., & Matsuzawa, Y. (2001). PPARˠ ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein. Diabetes, 50, 2094-2099. https://doi.org/10.2337/diabetes.50.9.2094
• Maeda, N., Shimomura, I., Kishida, K., Nishizawa, H., Matsuda, M., Nagaretani, H., Furuyama, N., Kondo, H., Takahashi, M., Arita, Y., Komuro, R., Ouchi, N., Kihara, S., Tochino, Y., Okutomi, K., Horie, M., Takeda, S., Aoyama, T., Funahashi, T., & Matsuzawa, Y. (2002). Diet-induced insulin resistance in mice lacking adiponectin/ACRP30. Nature Medicine, 8, 731-737. https://doi:10.1038/nm724
• Mao, X.L., Hong, J.Y., & Dong, L.Q. (2006). The adiponectin signaling pathway as a novel pharmacological target. Mini-Reviews in Medicinal Chemistry, 6(12), 1331-1340. https://doi: 10.2174/138955706778992978
• Matsuzawa, Y., Funahashi, T., Kihara, S., & Shimomura, I. (2004). Adiponectin and metabolic syndrome. Arteriosclerosis, Thrombosis, and Vascular Biology, 24(1), 29-33. https://doi.org/10.1161/01.ATV.0000099786.99623.EF
• Meeprom, A., Sompong, W., Suwannaphet, W., Yibchok-anun, S., & Adisakwattana, S. (2011). Grape seed extract supplementation prevents high-fructose diet-induced insulin resistance in rats by improving insulin and adiponectin signalling pathways. British Journal of Nutrition. 106, 1173-1181. https://doi.org/10.1017/S0007114511001589
• Mostafa-Hedeab, G., Shahataa, M., Alalkamy, E.F., Sabry, D., El-Nahass, E.S., Ewaıss, M., & Mahmoud, F. (2017). Allopurinol ameliorates high fructose diet-ınduced metabolic syndrome via up-regulation of adiponectin receptors and heme oxygenase-1 expressions in rats. Biomedical and Pharmacology Journal, 10(4), 1685-1694. https://doi: 10.13005/bpj/1280
• Nakagawa, T., Hu, H., Zharikov, S., Tuttle, K.R, Short, R.A., Glushakova, O., Ouyang, X., Feig, D.I., Block, E.R., Herrera-Acosta, J., Patel, J.M., & Johnson, R.J. (2006). A causal role for uric acid in fructose-induced metabolic syndrome. American Journal of Physiology-Renal Physiology, 290, 625-631. https://doi:10.1152/ajprenal.00140.2005
• Novelli, E.L.B., Diniz, Y.S., Galhardi, C.M., Ebaid, G.M., Rodrigues, H.G., Mani, F., Fernandes, A.A., Cicogna, A.C., & Novelli Filho, J.L. (2007). Anthropometrical parameters and markers of obesity in rats. Laboratory Animals, 41(1), 111-119. https://doi:10.1258/002367707779399518
• Okamoto, Y., Kihara, S., Funahashi, T., Matsuzawa, Y., & Libby, P. (2006). Adiponectin: a key adipocytokine in metabolic syndrome. Clinical Science, 110(3), 267-278. https://doi.org/10.1042/CS20050182
• Parker-Duffen, J.L., Nakamura, K., Silver, M., Zuriaga, M.A., MacLauchlan, S., Aprahamian, T.R., & Walsh, K. (2014). Divergent roles for adiponectin receptor 1 (AdipoR1) and AdipoR2 in mediating revascularization and metabolic dysfunction in vivo. The Journal of Biological Chemistry, 289(23), 16200-16213. https://doi:10.1074/jbc.M114.548115
• Rizkalla, S.W. (2010). Health implications of fructose consumption: A review of recent data. Nutrition and Metabolism, 7, 82. https://doi: 10.1186/1743-7075-7-82
• Roglans, N., Vila, L., Farre, M., Alegret, M., Sanchez, R.M., Vazquez-Carrera, M., & Laguna, J.C. (2007). Impairment of hepatic stat-3 activation and reduction of PPARα activity in fructose-fed rats. Hepatology, 45(3), 778-788. https://doi: 10.1002/hep.21499
• Ross, A.P., Bartness, T.J., Mielke, J.G., & Parent, M.B. (2009). A high fructose diet impairs spatial memory in male rats. Neurobiology of Learning and Memory, 92(3), 410-416. https://doi.org/10.1016/j.nlm.2009.05.007
• Sheludiakova, A., Rooney, K., & Boakes, R.A. (2012). Metabolic and behavioural effects of sucrose and fructose/glucose drinks in the rat. European Journal of Nutrition, 51(4), 445-454. https://doi.org/10.1007/s00394-011-0228-x
• Tomas, E., Tsao, T.S., Saha, A.K., Murrey, H.E., Zhang, C., Itani, S.I., Lodish, H.F., & Ruderman, N.B. (2002). Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation. Proceedings of the National Academy of Sciences, 99 (25), 16309-16313. https://doi.org/10.1073/pnas.222657499
• Tsuchida, A., Yamauchi, T., Ito, Y., Hada, Y., Maki, T., Takekawa, S., Kamon, J., Kobayashi, M., Suzuki, R., Hara, K., Kubota, N., Terauchi, Y., Froguel, P., Nakae, J., Kasuga, M., Accili, D., Tobe, K., Ueki, K., Nagai, R., & Kadowaki T. (2004). Insulin/Foxo1 pathway regulates expression levels of adiponectin receptors and adiponectin sensitivity. Journal of Biological Chemistry, 279, 30817-30822.
• Yamauchi, T., Kamon, J., Ito, Y., Tsuchida, A., Yokomizo, T., Kita, S., Sugiyama, T., Miyagishi, M., Hara, K., Tsunoda, M., Murakami, K., Ohteki, T., Uchida, S., Takekawa, S., Waki, H., Tsuno, N.H., Shibata, Y., Terauchi, Y., Froguel, P., Tobe, K., Koyasu, S., Taira, K., Kitamura, T., Shimizu, T., Nagai, R., & Kadowaki, T. (2003). Cloning of adiponectin receptors that mediate antidiabetic effects. Nature, 423, 762-769. https://doi: 10.1038/nature01705.
• Yamauchi, T., Nio, Y., Maki, T., Kobayashi, M., Takazawa, T., Iwabu, M., Okada-Iwabu, M., Kawamoto, S., Kubota, N., Kubota, T., Ito, Y., Kamon, J., Tsuchida, A., Kumagai, K., Kozono, H., Hada, Y., Ogata, H., Tokuyama, K., Tsunoda, M., Ide, T., Murakami, K., Awazawa, M., Takamoto, I., Froguel, P., Hara, K., Tobe, K., Nagai, R., Ueki, K., & Kadowaki, T. (2007). Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions. Nature Medicine, 13(3), 332-339. https://doi:10.1038/nm1557.