Efficacy of Pleth Variability Index (PVI) to Evaluate Intraoperative Fluid Management During Orthopedic Spinal Surgery: A Randomized Controlled Trial

Objective: To prevent complications during major surgery, it is important to monitor blood and fluid treatment. The Pleth Variability İndex (PVI) allows noninvasive assessment of fluid management. It is based on respiratory changes in arterial pulse pressure. In our study, we aimed to compare the management in terms of variations in PVI in response to fluid loading in the monitorization of intraoperative fluid management in major surgery using classical calculation method and CVP Method: The patients were randomized into two equal (n=50) groups. In Group C, the required amount of fluid replacement was carried out with crystalloid solutions using the 4-2-1 rule and by calculating fasting, maintenance, and insensible losses. In the PVI group, 250 mL of crystalloid solution was administered in 5 minutes to patients with a PVI greater than 14%, patients with a PVI less than 14% were administered a fluid infusion with an initial dose of 4 mL kg-1 h-1. Results: In the comparison of intraoperative fluid management the amount of intraoperative fluid replacement was 3522±1098.1 mL in Group C and 1914±542.86 mL in Group PVI (p0.05). Conclusion: It has been thought that PVI assessment is more valuable than CVP monitoring because it is noninvasive and thus provides better cardiac stabilization with less fluid replacement. It can also provide more accurate results when evaluating intravascular volume status.

Ortopedik Spinal Cerrahi Olgularında İntraoperatif Sıvı Yönetimini Değerlendirmede Pleth Değişkenlik İndeksinin Etkinliği: Randomize Kontrollü Çalışma

Amaç: Majör cerrahilerde komplikasyonları önlemek için, kan ve sıvı tedavisini izlemek önemlidir. “Pleth Değişkenlik İndeksi” (PDİ) sıvı tedavisinin invaziv olmayan ölçümüne olanak sağlayan, temeli arteriyel nabız basıncındaki solunumsal değişikliklere dayanan bir yöntemdir. Çalışmamızda, majör cerrahide intraoperatif sıvı yönetiminin, klasik hesaplama yöntemi ve SVB ile takibinin, sıvı yüklemesine verilen PVI değişikliklerine göre yönetimin karşılaştırılması amaçlanmıştır. Yöntem: Hastalar randomize olarak 2 eşit gruba (n=50) ayrıldı. Grup C’de sıvı gereksinimi açlık, idame ve insensibl kayıp 4-2-1 kuralına göre hesaplanarak kristalloid ile karşılandı. Grup PDİ’de PDİ değeri 14’ün üstünde olan hastalara 250 mL kristalloid 5 dk’da gidecek şekilde verildi. PDİ değeri 14’ün altında olan hastalara 4 mL kg-1 sa-1 sıvı infüzyonu açıldı. Bulgular: Grupların intraoperatif sıvı yönetimlerinin karşılaştırmasında; Grup C’de intraoperatif verilen sıvı miktarı 3522±1098.1 mL ve Grup PDİ de intraoperatif verilen sıvı miktarı 1914±542.86 ml (p

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1. Van Regenmortel N, Jorens PG, Malbrain ML. Fluid management before, during and after elective surgery. Curr Opin Crit Care. 2014;20:390-5. https://doi.org/10.1097/MCC.0000000000000113

2. Holte K, Sharrock NE, Kehlet H. Pathophysiology and clinical implications of perioperative fluid excess. Br J Anaesth. 2002;89:622-32. https://doi.org/10.1093/bja/aef220

3. Feldman JM, Sussman E, Singh D, Friedman BJ. Is the pleth variability index a surrogate for pulse pressure variation in a pediatric population undergoing spine fusion? Paediatr Anaesth. 2012;22:250-5. https://doi.org/10.1111/j.1460-9592.2011.03745.x

4. Renner J, Broch O, Gruenewald M, et al. Non-invasive prediction of fluid responsiveness in infants using pleth variability index. Anaesthesia. 2011;66:582-9. https://doi.org/10.1111/j.1365-2044.2011.06715.x

5. Michard F. Changes in arterial pressure during mechanical ventilation. Anesthesiology. 2005;103:419-28. https://doi.org/10.1097/00000542-200508000-00026

6. Perel A, Minkovich L, Preisman S, Abiad M, Segal E, Coriat P. Assessing fluid-responsiveness by a standardized ventilatory maneuver: the respiratory systolic variation test. Anesth Analg. 2005;100:942-5. https://doi.org/10.1213/01.ANE.0000146939.66172.AE

7. Tavernier B, Makhotine O, Lebuffe G, Dupont J, Scherpereel P. Systolic pressure variation as a guide to fluid therapy in patients with sepsis-induced hypotension. Anesthesiology. 1998;89:1313-21. https://doi.org/10.1097/00000542-199812000-00007

8. Sebastiani A, Philippi L, Boehme S et al. Perfusion index and plethysmographic variability index in patients with interscalene nerve catheters. Can J Anaesth. 2012;59:1095-1101. https://doi.org/10.1007/s12630-012-9796-3

9. Lopes MR, Oliveira MA, Pereira VO, Lemos IP, Auler JO Jr, Michard F. Goal-directed fluid management based on pulse pressure variation monitoring during highrisk surgery: a pilot randomized controlled trial. Crit Care. 2007;11:R100. https://doi.org/10.1186/cc6117

10. Cannesson M, Delannoy B, Morand A et al. Does the Pleth variability index indicate the respiratory-induced variation in the plethysmogram and arterial pressure waveforms? Anesth Analg. 2008;106:1189-94. https://doi.org/10.1213/ane.0b013e318167ab1f

11. Stawicki SP, Kent A, Patil P et al. Dynamic behavior of venous collapsibility and central venous pressure during standardized crystalloid bolus: A prospective, observational, pilot study. Int J Crit Illn Inj Sci. 2015;5:80-4. https://doi.org/10.4103/2229-5151.158392

12. Marik PE, Baram M, Vahid B. Does central venous pressure predict fluid responsiveness? A systematic review of the literature and the tale of seven mares. Chest. 2008;134:172-8. https://doi.org/10.1378/chest.07-2331

13. Bouchard J, Soroko SB, Chertow GM et al. Fluid accumulation, survival and recovery of kidney function in critically ill patients with acute kidney injury. Kidney Int. 2009;76:422-7. https://doi.org/10.1038/ki.2009.159

14. Bacchin MR, Ceria CM, Giannone S et al. Goal directed fluid therapy based on stroke volume variation in patients undergoing major spine surgery in the prone position: A cohort study. Spine (Phila Pa 1976). 2016;41:1131-7. https://doi.org/10.1097/BRS.0000000000001601

15. Morgan GE, Mikhail MS, Murray MJ, Larson CP. Fluid management and transfusion. In: Clinical Anesthesiology, Fifth Ed. New York: The MacGraw-Hill Companies, 2014:153-8.

16. Morgan GE, Mikhail MS, Murray MJ, Larson CP. Fluid management and transfusion in Clinical Anesthesiology, Fifth Ed., The MacGraw-Hill Companies, New York, 2014:175-179.

17. Cannesson M, Attof Y, Rosamel P et al. Respiratory variations in pulse oximetry plethysmographic waveform amplitude to predict fluid responsiveness in the operating room. Anesthesiology. 2007;106:1105-11. https://doi.org/10.1097/01.anes.0000267593.72744.20

18. Préau S, Dewavrin F, Soland V et al. Hemodynamic changes during a deep inspiration maneuver predict fluid responsiveness in spontaneously breathing patients. Cardiology Research and Practice. 2012;2012:191807. https://doi.org/10.1155/2012/191807

19. Bundgaard-Nielsen M, Secher NH, Kehlet H. ‘Liberal’ vs. ‘restrictive’ perioperative fluid therapy--a critical assessment of the evidence. Acta Anaesthesiol Scand. 2009;53:843-51. https://doi.org/10.1111/j.1399-6576.2009.02029.x

20. Kristensen SD, Knuuti J, Saraste A et al. 2014 ESC/ESA Guidelines on noncardiac surgery: cardiovascular assessment and management: The Joint Task Force on noncardiac surgery: Cardiovascular assessment and management of the European Society of Cardiology (ESC) and the European Society of Anaesthesiology (ESA). Eur J Anaesthesiol. 2014;31:517-73.

21. Carson JL, Terrin ML, Noveck H et al. Liberal or restrictive transfusion in high-risk patients after hip surgery. N Engl J Med. 2011;365:2453-62. https://doi.org/10.1056/NEJMoa1012452

22. Holte K, Foss NB, Andersen J. Liberal or restrictive fluid administration in fast-track colonic surgery: a randomized, double blind study. Br J Anaesthesia. 2007;99:500-8. https://doi.org/10.1093/bja/aem211

23. Jia FJ, Yan QY, Sun Q, Tuxun T, Liu H, Shao L. Liberal versus restrictive fluid management in abdominal surgery: a meta-analysis. Surg Today. 2017;47:344-56. https://doi.org/10.1007/s00595-016-1393-6

24. Corcoran T, Rhodes JE, Clarke S, Myles PS, Ho KM. Perioperative fluid management strategies in major surgery: a stratified meta-analysis. Anesth Analg. 2012;114:640-51. https://doi.org/10.1213/ANE.0b013e318240d6eb

25. Yu Y, Dong J, Xu Z, Shen H, Zheng J. Pleth variability index-directed fluid management in abdominal surgery under combined general and epiduralanesthesia. J Clin Monit Comput. 2015;29:47-52. https://doi.org/10.1007/s10877-014-9567-5

26. Forget P, Lois F, de Kock M. Goal-directed fluid management based on the pulse oximeter-derived pleth variability index reduces Lactate levels and improves fluid management. Anesth Analg. 2010;111:910-4. https://doi.org/10.1213/ANE.0b013e3181eb624f

27. Willner D, Spennati V, Stohl S, Tosti G, Aloisio S, Bilotta F. Spine Surgery and Blood Loss: Systematic Review of Clinical Evidence. Anesth Analg. 2016;123:1307-15. https://doi.org/10.1213/ANE.0000000000001485
Anestezi Dergisi-Cover
  • ISSN: 1300-0578
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 1993
  • Yayıncı: Betül Kartal
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