Yusuf Ali Altuncı, Sercan Yalçınlı, Mehmet Efe

Nadir Bir Semptom ve Önemli Bir Hastalık : Hiperpigmentasyon ve Primer Adrenal Yetmezlik

Amaç Adrenal yetmezliğin klinik semptomları spesifik değildir ve bu nedenle yanlış tanı yaygındır. Hiperpigmentasyon, primer adrenal yetmezlik tanısı için spesifik bir bulgudur. Bu olgu primer adrenal yetmezlik tanısında hiperpigmentasyon varlığının önemini vurgulamak amacıyla sunuldu.OlguBilinen hastalık öyküsü olmayan 66 yaşında erkek hasta acil servisimize halsizlik, bulantı ve kusma şikayetleri ile başvurdu. İlk değerlendirmesinde kan basıncı 71/55 mmHg olarak belirlendi. Fizik muayenede cilt renginde koyulaşma, el ve dilde hiperpigmentasyon görüldü. Fizik muayenede başka anlamlı bulgu saptanmadı. Hastanın laboratuvar bulgularında Adrenokortikotropik hormon (ACTH)> 1250 pg / mL (referans değeri:

A Rare Symptom And An Important Disease:Hyperpigmentation And Primary Adrenal Insufficiency

Aim Clinical symptoms of adrenal insufficiency are nonspecific and thus misdiagnosis is common. Hyperpigmentation is a specific finding for the diagnosis of primary adrenal insufficiency. This case report is presented to emphasize the importance of the presence of hyperpigmentation in the definition of primary adrenal insufficiency.CaseA 66-year-old male with no previous history of disease presented to our emergency department with complaints of weakness, nausea, and vomiting. On his initial evaluation, blood pressure was 71/55 mmHg. Physical examination revealed darkening of skin color and increased pigmentation on hands and tongue. There were no other significant findings on physical examination. The laboratory findings of the patient were: Adrenocorticotropic hormone (ACTH)>1250 pg/mL (reference value:

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