Ömer SALT, Çağdaş DERDİYOK, Mustafa Burak SAYHAN

Kemoterapiye bağlı gelişen El-Ayak Sendromu Olgusu

Antrasiklin grubu bir antineoplastik ilaç olan Lipozomal doksorubisin (LD), agresif seyirli non-Hodgkin lenfoma, dirençli over ve meme kanserleri ve AIDS ile ilişkili Kaposi sarkomunun tedavisinde kullanılmaktadır. Bu tür kemoterapötiklerin nadir, doza bağımlı yan etkilerinden birisi olan “el-ayak sendromu”, hastaların ilk olarak acil servise başvurmaları nedeniyle bilinmesi gereken bir yan etkidir. Bu yazıda metastatik over karsinomu nedeniyle lipozomal doksorubisin tedavisi alımı sonrası acil servise ellerde ve ayaklarda kızarıklık şişlik ve ağrı şikayetleriyle başvuran ve el ayak sendromu tanısı konulan bir vakadan bahsedilecektir.

Anahtar Kelimeler:

Acil servis, lipozomal doksorubisin, el ayak sendromu

A case of Hand-Foot Syndrome Due to Chemotherapy

Liposomal doxorubicin (LD)that is an anthracycline group antineoplastic drug, is used in the treatment of aggressive non-Hodgkin's lymphoma, resistant ovarian and breast cancers and AIDS-related Kaposi's sarcoma. A rare and dose-dependent side effect of such chemotherapeutics, is Hand-foot syndrome and it should be known by emergency physicians because of the patients' first contact with the hospital is in emergency department. In this article, we present a case who was admitted to the emergency department with complaints of redness, swelling and pain in the hands and feet after the liposomal doxorubicin treatment for metastatic ovarian carcinoma.

Keywords:

Emergency department, liposomal doxorubicin, hand-foot syndrome,

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