Türk Bir Popülasyonda Normal Tiroid Teknesyum- 99m Perteknetat Alım Aralığının Belirlenmesi

Amaç: Bu çalışmada Türk bir popülasyonda normal tiroid teknesyum-99m perteknetat alım aralığını belirlemek amaçlanmıştır.Yöntem: Retrospektif çalışmamız paratiroid adenom lokalizasyonu için uygulanan paratiroid sintigrafisinin bir bileşeni olarak teknesyum-99m perteknetat ile tiroid sintigrafisi yapılan ardışık 73 (54 kadın, 19 erkek) ötiroid hasta içerdi. Her hasta için 20. dakikada tiroid teknesyum- 99m perteknetat alım değeri hesaplandı.Bulgular: Ortalama hasta yaşı 56,4±15,2 yıl, ortalama tiroid uyarıcı hormon düzeyi 1,15±0,48 uIU/mL idi. Medyan ve çeyrekler arası aralık teknesyum-99m perteknetat alım değerleri sırasıyla %0,8 ve %0,56–1,15 idi. Belirlenen normal tiroid teknesyum-99m perteknetat alım aralığı %0,26–1,64 oldu. Yaş ve teknesyum-99m perteknetat alımı arasında negatif korelasyon gözlendi (r=-0,33; p=0,002).Sonuç: Türkiye’de kullanımda olanlara kıyasla anlamlı biçimde daha düşük değerlere dayanan yeni normal tiroid teknesyum-99m perteknetat alım aralığımızın, İstanbul nüfusunda tiroid hastalıklarında tiroid fonksiyonu değerlendirmelerinde kullanılmaya uygun olduğu savındayız.

Anahtar Kelimeler:

Tiroid;, teknesyum-99m perteknetat;, tiroid sintigrafisi

Determination of the Normal Range for Thyroid Uptake of Technetium-99m Pertechnetate in a Turkish population

Aim: This study aimed to determine the normal range for thyroid uptake of technetium-99m (99mTc) pertechnetate in a Turkish population.Methods: The retrospective study included 73 (54 females, 19 males) consecutive euthyroid patients, all of whom underwent thyroid scintigraphy using 99mTc-pertechnetate as a component of parathyroid scintigraphy for parathyroid adenoma localization. The value of thyroid uptake of 99mTc-pertechnetate at the 20th minute was calculated for each patient.Results: The mean patient age was 56.4±15.2 years; the mean thyroid-stimulating hormone level was 1.15±0.48 uIU/mL. The median and interquartile range values of 99mTc-pertechnetate uptake were 0.8% and 0.56–1.15%, respectively. The normal range for thyroid uptake of 99mTc-pertechnetate was determined to be 0.26–1.64%. There was a negative correlation between 99mTc-pertechnetate uptake and age (r =-0.33, p=0.002).Conclusion: We propose that our new normal range for thyroid uptake of 99mTc-pertechnetate based on significantly lower values compared with those currently in use in Turkey is appropriate for use to evaluate thyroid function in thyroid disorders in the population of Istanbul.

Keywords:

technetium-99m pertechnetate;, Thyroid;, thyroid scintigraphy,

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