KISA BAĞIRSAK SENDROMUNDA TIBBİ BESLENME TEDAVİSİ VE BAĞIRSAK ADAPTASYONUNDA BESİN MÜDAHALELERİ

İnce bağırsağın 'normal' uzunluğu 320-800 cm arasında değişmektedir. İnce bağırsak uzunluğunun 200 cm'den daha az olması kısa bağırsak sendromu olarak tanımlanmaktadır. Kısa bağırsak sendromu, esas olarak ince bağırsağın anatomik ve/veya fonksiyonel kaybından sonra ortaya çıkan ve ishal, steatore, ağırlık kaybı, malnütriyon, malabsorbsiyon, dehidrasyon gibi bulgularla kendini gösteren klinik bir tablodur. Bu tablonun hafiflemesi için uygun beslenme tedavisi planlanmalı, kaybedilen sıvı ve elektrolitler yerine konulmalıdır. Hastalığın altında yatan faktörler ve cerrahi işlem türü dikkate alınarak beslenme planı oluşturulmalıdır. Kısa bağırsak sendromunda tedavinin en temel hedefi bağırsak adaptasyonunun sağlanmasıdır. Bağırsak adaptasyonu için son zamanlarda glutamin, büyüme hormonu, balık yağı ve probiyotikler-prebiyotikler gibi besin müdahaleleri araştırılmaktadır. Bu derlemenin amacı kısa bağırsak sendromunda tıbbi beslenme tedavisini ve bağırsak adaptasyonunda besin müdahalelerini incelemektir.

MEDICAL NUTRITION THERAPY IN SHORT BOWEL SYNDROME AND FOOD INTERVENTIONS IN INTESTINAL ADAPTATION

The 'normal' length of the small intestine ranges from 320 to 800 cm. short bowel syndrome is defined as the small bowel length less than 200 cm. Short bowel syndrome is a clinical manifestation that occurs mainly after anatomical and / or functional loss of small intestine and presents with diarrhea, steatorrhea, weight loss, malnutrition, malabsorption, dehydration. Therefore, appropriate nutritional therapy should be planned, and lost fluid and electrolytes should be replaced. A nutritional plan should be drawn up considering other factors affecting the disease and the type of surgical procedure. The main goal of treatment in short bowel syndrome is to achieve bowel adaptation. Nutritional interventions such as glutamine, growth hormone, fish oil and probiotics-prebiotics have recently been investigated for intestinal adaptation. The aim of this review is to examine medical nutrition therapy in short bowel syndrome and nutritional interventions in bowel adaptation.

Keywords:

Intestinal adaptation, glutamine, short bowel syndrome prebiotics-probiotics, medical nutrition therapy,

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