Palestine is a crucial and well-known place for humanity in general for the region in particular. Thearea is important for religious, cultural, political, strategic and economic matters. Judaism,Christianity and Islam are connected with the region. The well-known world empires and culturesleft their ethnic, cultural and/or political marks in the life of regional people. The lucrative energystocks are either located or connected with the region. The strategic location, military andeconomic capabilities of Turkey and Israel is significant and noteworthy in the region. They haveplayed roles in the recent past and it seems they will continue to play in the near future. The bothcountries relationship required delicate policies due to their domestic and international sensitivities.There are ethnic and religious rivalries as well as political and economic clash of interests in theregion. Alliances and co-operations in various fields shaped the recent history of the region. Theregion seems to be the most interesting arenas of political, economic, cultural and militarymanoeuvres of the influential world and regional powers. Turkey and Israel will play their active orpassive roles in the wider scenarios accordance with their influences in regional and/orinternational politics. The relationship will be affected either upwards or downwards depending ontheir domestic and international perspectives of the issues. Regional and internationaldevelopments are influential in shaping consistency of bilateral relations and regional peace.Key words: Turkey, Israel, Palestine, Turkish-Israeli relations, Turkish economy, foreign relations.