Yaşlılarda Epilepsi
Nöbetler etiyoloji, klinik bulgular ve prognoz açısından yaşlı ve genç hastalar arasında önemli farklılıklar gösterir. Yaşlılarda epilepsi insidans ve prevalansı genç erişkinlerden ve çocuklardan belirgin olarak daha yüksektir. Yaşlılarda en sık görülen nöbet nedenleri serebrovasküler olaylar, nörodejeneratif hastalıklar, travma ve metabolik ensefalopatilerdir. Yaşlı bir hastada epilepsi tanısı atipik klinik bulguların sık görülmesi nedeniyle zorlaşabilmektedir. Antiepileptik ilaç tedavisi yaşlanmayla ilişkili fi zyolojik farmakokinetik ve farmakodinamik değişiklikler nedeniyle doz ayarlamaları gerektirir
Epilepsy in the Elderly
Seizures differ signifi cantly between the elderly and younger patients according to the etiology, clinical fi ndings and prognosis. The incidence and prevalence of epilepsy is signifi cantly higher in the elderly than in young adults and children. The most common causes of seizures in the elderly are cerebrovascular events, neuro-degenerative diseases, trauma and metabolic encephalopathies. The diagnosis of epilepsy in older patients is usually diffi cult due to the commonly encountered atypical clinical fi ndings. Antiepileptic drug therapy requires dose adjustments due to the physiological pharmacokinetic and pharmacodynamic changes associated with aging
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- Yayın Aralığı: Yılda 3 Sayı
- Başlangıç: 2015
- Yayıncı: Akdeniz Üniversitesi Tıp Fakültesi
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