Konik Işınlı Bilgisayarlı Tomografi ile Görüntüleme Sonrası Amalgam Dolgulardan Cıva Salınımının in-vitro Gösterimi

Amaç: Çalışmada amalgam dolgulardan konik ışın demetli bilgisayarlı tomografi KIBT ile görüntüleme sonrası oluşacak cıva sızıntısını test etmeyi amaçladık.Gereç ve Yöntemler: Çalışma Kırıkkale Üniversitesi Etik Kurul onayı alınarak yapıldı ve her dişin kullanımı için hastalardan yazılı onam alındı. Çeşitli nedenlerle çekilmiş 40 adet çürüksüz molar ve premolar dişe 2 yüzlü kaviteler açıldı, klinik prosedüre uygun olarak amalgam dolgular yapıldı. Dişler rastgele kontrol ve deney grubu olmak üzere iki gruba ayrıldı. Amalgamın sertleşme süreci tamamlandıktan bir hafta sonra dişler 20ml yapay tükürük Fusayama solüsyonu içeren tüpler içerisine kondu. Kontrol grubu 24 saat bekletilirken; deney grubundaki dişler tüpler içerisinde KIBT ile belirli parametrelerde görüntülendi. Görüntülemeyi takip eden 24 saat sonrasında dişler tüplerden çıkarılıp cıva konsantrasyonu için İndüktif Olarak Eşleştirilmiş Plazma – Optik Eisyon Spektrometresi ICP-OES ile analize gönderildi. Bulgular: KIBT ile ekspoze edilen amalgam dolgulu dişlerden 24 saat içerisinde yapay tükürüğe salınan cıva miktarı ortalama 0,268±0,197 ppm iken, kontrol grubunda bu değer 0,141±0,152 ppm olarak saptandı.Sonuç: Bu bulgular ışığında, deneysel koşullarda, amalgam dolgulu dişlerde KIBT ile gerçekleştirilen görüntüleme cıva salınımını artırmaktadır diyebiliriz

Anahtar Kelimeler:

Amalgam, Cıva, Konik ışın demetli bilgisayarlı tomografi

In-Vitro Representation of Mercury Release from Amalgam Restorations after Cone-Beam Computed Tomographic Imaging

Objective: In this study, we aimed to evaluate the mercury leakage of from dental amalgam fillings after cone beam computed tomography CBCT scan.Material and Methods: This study was approved by the Kırıkkale University Clinical Research Ethics Committee. Written informed consent was obtained from the patients for the use of the extracted teeth in this project. Forty caries-free molar or premolar teeth that had been extracted for clinical indications were used. Two-sided cavities were prepared and amalgam fillings applied to each tooth. One week after amalgam setting process, two groups of 20 randomly selected teeth were placed in 20 mL of artificial saliva. In the experiment group, tubes were immediately exposed with CBCT. The control group was kept under normal conditions. Twenty-four hours later the teeth were removed from the artificial saliva, and the saliva was analyzed for mercury content by using Inductively Coupled Plasma Optical Emission Spectrometry. Results: The amount of mercury released to the artificial saliva was found to be 0.268±0.197 ppm in CBCT group within 24 hours, whereas this value was 0.141±0.152 ppm in the control group.Conclusion: The findings of this study indicated that CBCT imaging of teeth restored with amalgam leads an increase in mercury leakage under experimental conditions

Keywords:

Amalgam, Mercury, Cone beam computed tomography,

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Mackert JR Jr, Wahl MJ. Are there acceptable alternatives to amalgam. J Calif Dent Assoc 2004; 32:601-10.
American Dental Association, Survey Center. The 1999 survey of dental services rendered. Chicago: American Dental Association, 2002.
Guzzi G, Grandi M, Cattaneo C, Calza S, Minoia C, Ronchi A, Gatti A, Severi G. Dental amalgam and mercury levels in autopsy tissues: Food for thought. Am J Forensic Med Pathol 2006; 27:42-5.
Nylander M, Friberg L, Lind B. Mercury concentrations in the human brain and kidneys in relation to exposure from dental amalgam fillings. Swed Dent J 1987; 11:179- 87.
Saxe SR, Wekstein MW, Kryscio RJ, Henry RG, Cornett CR, Snowdon DA, Grant FT, Schmitt FA, Donegan SJ, Wekstein DR, Ehmann WD, Markesbery WR. Alzheimer’s disease, dental amalgam and mercury. J Am Dent Assoc 1999; 130:191-9.
Sweeney M, Creanor SL, Smith RA, Foye RH. The release of mercury from dental amalgam and potential neurotoxicological effects. J Dent 2002; 30:243-50.
Ritchie KA, Gilmour WH, Macdonald EB, Burke FJ, McGowan DA, Dale IM, Hammersley R, Hamilton RM, Binnie V, Collington D. Health and neuropsychological functioning of dentists exposed to mercury. Occup Environ Med 2002; 59:287-93.
DeRouen TA, Martin MD, Leroux BG, Townes BD, Woods JS, Leitão J, Castro-Caldas A, Luis H, Bernardo M, Rosenbaum G, Martins IP. Neurobehavioral effects of dental amalgam in children: A randomized clinical trial. JAMA 2006;19(295):1784-92.
Okabe T, Butts MB, Mitchell RJ. Changes in the microstructures of silver-tin and admixed high-copper amalgams during creep. J Dent Res 1983;62:37-43.
Batur YB, Haznedaroğlu F, Aroğuz AZ, Özer K. Çiğneme fonksiyonuna giren amalgam dolgulu dişlerden ve retrograd amalgam dolgulardan kan ve idrara cıva geçişinin incelenmesi. J Istanb Univ Fac Dent 2012; 46:43-54.
Furhoff AK, Tomson Y, Ilie M, Bagedahl-Strindlund M, Larsson KS, Sandborgh-Englund G, Torstenson B, Wretlind K. A multidisciplinary clinical study of patients suffering from illness associated with release of mercury from dental restorations: Medical and odontological aspects. Scand J Prim Health Care 1998; 16:247-52.
Homme KG1, Kern JK, Haley BE, Geier DA, King PG, Sykes LK, Geier MR. New science challenges old notion that mercury dental amalgam is safe. Biometals 2014;27: 19-24.
Björkman L, Lind B. Factors influencing mercury evaporation rate from dental amalgam fillings. Scand J Dent Res 1992; 100:354-60.
Kursun S, Öztaş B, Atas H, Taştekin M. Effects of X-rays and magnetic resonance imaging on mercury release from dental amalgam into artificial saliva. Oral Radiol 2014; 30:142-6.
Lissac M, Metrop D, Brugirard J, Coudert JL, Pimmel P, Briguet A, Revel D, Amiel M . Dental materials and magnetic resonance imaging. Invest Radiol 1991;26:40-5.
Yilmaz, S, Misirlioğlu M. The effect of 3 T MRI on microleakage of amalgam restorations. Dentomaxillofac Radiol 2013; 42(8):20130072.
Görgülü S1, Ayyildiz S, Kamburoglu K, Gökçe S, Ozen T. Effect of orthodontic brackets and different wires on radiofrequency heating and magnetic field interactions during 3-T MRI. Dentomaxillofac Radiol 2014; 43(2):20130356.
Yilmaz S, Adisen MZ. Ex Vivo Mercury Release from dental amalgam after 7.0-T and 1.5-T MRI. Radiology 2018;26:172597.